The CD226 gene in susceptibility of rheumatoid arthritis in the Chinese Han population

Rheumatology International

Volumn 32, Issue 5, 2012, Pages 1299-1304

  Du, Yan ^a   Shen, Ling Xun ^a   Yu, Li Kai ^a   Song, You ^a   Zhu, Jian Fang ^b   Du, Rong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

CD226 gene; Genetic association; Rheumatoid arthritis; Single nucleotide polymorphism

Indexed keywords

ADULT; ARTICLE; CD226 GENE; CHINESE; CONTROLLED STUDY; DNA SEQUENCE; ETHNIC DIFFERENCE; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RHEUMATOID ARTHRITIS; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ARTHRITIS, RHEUMATOID; ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHINA; COLOMBIA; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE DISEQUILIBRIUM; LOGISTIC MODELS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MULTIVARIATE ANALYSIS; ODDS RATIO; PHENOTYPE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK ASSESSMENT; RISK FACTORS;

EID: 84863613091     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-011-1796-z     Document Type: Article

References (20)

1. Silman AJ, Pearson JE (2002) Epidemiology and genetics of rheumatoid arthritis. Arthritis Res 4(Suppl 3):S265-S272
2. Silman AJ, MacGregor AJ, Thomson W, Holligan S, Carthy D, Farham A et al (1993) Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol 32(10):903-907
3. w4 with rheumatoid arthritis. N Engl J Med 298(16):869-871
4. Bowes J, Barton A (2008) Recent advances in the genetics of RA susceptibility. Rheumatology (Oxford) 47(4):399-402
5. Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V et al (2007) Robust association of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 39(7):857-864
6. Douroudis K, Nemvalts V, Rajasalu T, Kisand K, Uibo R (2009) The CD226 gene in susceptibility of type 1 diabetes. Tissue Antigens 74(5):417-419
7. Hafler JP, Maier LM, Cooper JD, Plagnol V, Hinks A, Simmonds MJ et al (2009) CD226 Gly307Ser association with multiple diseases. Genes Immun 10(1):5-10
8. Wieczorek S, Hoffjan S, Chan A, Rey L, Harper L, Fricke H et al (2009) Novel association of the CD226 (DNAM-1) Gly307Ser polymorphism in Wegener's granulomatosis and confirmation for multiple sclerosis in German patients. Genes Immun 10(6):591-595
9. Douroudis K, Kingo K, Silm H, Reimann E, Traks T, Vasar E et al (2010) The CD226 Gly307Ser gene polymorphism is associated with severity of psoriasis. J Dermatol Sci 58(2):160-161
10. Klimiuk PA, Yang H, Goronzy JJ, Weyand CM (1999) Production of cytokines and cytokines and metalloproteinases in rheumatoid synovitis is T cell dependent. Clin Immunol 90(1):65-78
11. Shibuya K, Shirakawa J, Kameyama T, Honda S, Tahara-Han-aoka S, Miyamoto A et al (2003) CD226 (DNAM-1) is involved in lymphocyte function-associated antigen-1 costimulatory signal for native T cell differentiation and proliferation. J Exp Med 198(12):1829-1839
12. Shibuya K, Lanier LL, Phillips JH, Ochs HD, Shimizu K, Nakayama E et al (1999) Physical and functional association of LFA-1withDNAM-1adhesionmolecule. Immunity11(15):615-623
13. Dardalhon V, Schubart AS, Reddy J, Meyers JH, Monney L, Sabatos CA et al (2005) CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. J Immunol 175(3):1558-1565
14. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31(3):315-324
15. Maiti AK, Kim-Howard X, Viswanathan P, Guillen L, Qian X, Rojas-Villarraga A et al (2010) Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases. Rheumatology (Oxford) 49(7):1239-1244
16. Bottino C, Castriconi R, Pende D, Rivera P, Nanni M, Carn-emolla B et al (2003) Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J Exp Med 198(4):557-567
17. Tabata H, Hara M, Kitani A, Hirose T, Norioka K, Harigai M et al (1989) Expression of TliSA1 on T cells from patients with rheumatoid arthritis and systemic lupus erythematosus. Clin Immunol Immunopathol 52(3):366-375
18. Shibuya A, Lanier LL, Phillips JH (1998) Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX-1 accessory molecule-1 receptor. J Immunol 161(4):1671-1676
19. Ueda H, Howson JM, Esposito L, Heward J, Snook H, Chamberlain G et al (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423(6939):506-511
20. Shirakawa J, Shibuya K, Shibuya A (2005) Requirement of the serine at residue 329 for lipid raft recruitment of DNAM-1 (CD226). Int Immunol 17(3):217-223