Sesquiterpene lactones from inula hupehensis inhibit nitric oxide production in RAW2647 macrophages

Planta Medica

Volumn 78, Issue 10, 2012, Pages 1002-1009

  Qin, Jiang Jiang ^a,d   Zhu, Jia Xian ^a   Zeng, Qi ^a   Cheng, Xiang Rong ^a   Zhang, Shou De ^a   Jin, Hui Zi ^a   Zhang, Wei Dong ^a,b,c  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Asteraceae; Inula hupehensis Ling.; nitric oxide production; sesquiterpene lactones; structure activity relationships

Indexed keywords

11 EPISUNDIVERSIFOLIDE; 11(13) DEHYDROIVAXILLIN; 11ALPHA,13 DIHYDROTOMENTOSIN; 11BETA,13 DIHYDRO 4H TOMENTOSIN; 14 ACETOXY 6ALPHA HYDROXYCARABRONE; 1BETA,10ALPHA EPOXIDE 8BETA ACETOXY 9BETA HYDROXYEUPATOLIDE; 3 OXO 6ALPHA HYDROXYEUDESMA 4(5),11(13) DIEN 12,8BETA OLIDE; 4ALPHA,6ALPHA DIHYDROXY 5ALPHA,11ALPHAH EUDESMA 12,8BETA OLIDE; 4ALPHA,6ALPHA DIHYDROXY 5ALPHAH EUDESMA 2(3),11(13) DIEN 12,8BETA OLIDE; 4H TOMENTOSIN; 6ALPHA ACETOXYTOMENTOSIN; 6ALPHA HYDROXY 4 EPISEPTUPLINOLIDE; 6ALPHA HYDROXY 8ALPHAH SECOEUDESMANOLIDE; 6ALPHA HYDROXYCARABRONE; 6ALPHA HYDROXYISOALANTOLACTONE; 6ALPHA HYDROXYISOALLOALANTOLACTONE; 6ALPHA HYDROXYTOMENTOSIN; 6BETA HYDROXYTOMENTOSIN; 8 EPIXANTHATIN 1BETA,5BETA EPOXIDE; 9BETA ACETOXYEUPATOLIDE; 9BETA HYDROXYEUPATOLIDE; AMINOGUANIDINE; ARGLANIN; CARABRONE; INUCHINENOLIDE A; NITRIC OXIDE; SESQUITERPENE LACTONE; SUNDIVERSIFOLIDE; TAUREMISIN; TOMENTOSIN; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; INFRARED SPECTROSCOPY; INULA; INULA HUPEHENSIS; MACROPHAGE; MASS SPECTROMETRY; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CELL SURVIVAL; INHIBITORY CONCENTRATION 50; INULA; LACTONES; LIPOPOLYSACCHARIDES; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE; PLANT COMPONENTS, AERIAL; SESQUITERPENES; SESQUITERPENES, GERMACRANE; STRUCTURE-ACTIVITY RELATIONSHIP;

ASTERACEAE; INULA HUPEHENSIS;

EID: 84863605572     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1298621     Document Type: Article

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