Somatic GNAS mutation causes widespread and diffuse pituitary disease in acromegalic patients with McCune-Albright syndrome

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 7, 2012, Pages 2404-2413

  Vortmeyer, Alexander O ^a   Gläsker, Sven ^a   Mehta, Gautam U ^a   Abu Asab, Mones S ^b   Smith, Jonathan H ^a   Zhuang, Zhengping ^a   Collins, Michael T ^c   Oldfield, Edward H ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PROLACTIN; SOMATOMEDIN C;

ACROMEGALY; ADENOHYPOPHYSIS DISEASE; ADULT; ALBRIGHT SYNDROME; ARTICLE; CASE REPORT; CASE STUDY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; GENE; GENE MUTATION; GENETIC ANALYSIS; GNAS GENE; GROWTH HORMONE RELEASE; GROWTH HORMONE SECRETING ADENOMA; GROWTH HORMONE SECRETING CELL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERPLASIA; HYPOPHYSECTOMY; HYPOPHYSIS ADENOMA; MALE; MALIGNANT TRANSFORMATION; MICRODISSECTION; NATIONAL HEALTH ORGANIZATION; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEOTIDE SEQUENCE; PATHOGENESIS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REMISSION; TRANSSPHENOIDAL HYPOPHYSECTOMY; TREATMENT FAILURE; TREATMENT OUTCOME;

ACROMEGALY; ADENOMA; ADULT; DNA MUTATIONAL ANALYSIS; FEMALE; FIBROUS DYSPLASIA, POLYOSTOTIC; GROWTH HORMONE-SECRETING PITUITARY ADENOMA; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MUTATION, MISSENSE; PITUITARY DISEASES; YOUNG ADULT;

EID: 84863569161     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-1274     Document Type: Article

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