Oocytes use the plasminogen-plasmin system to remove supernumerary spermatozoa

Human Reproduction

Volumn 27, Issue 7, 2012, Pages 1985-1993

  Coy, Pilar ^a   Jimnez Movilla, Mara ^a   Garca Vzquez, Francisco A ^a   Mondjar, Irene ^a   Grulln, Luis ^a   Romar, Raquel ^a  

^a Physiology of Reproduction Group   (Spain)

Author keywords

fertilization; plasmin; plasminogen; plasminogen activators; spermzona pellucida binding

Indexed keywords

PLASMIN; PLASMINOGEN; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

ANIMAL CELL; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; FIBRINOLYSIS; GAMETE; IMMUNOCYTOCHEMISTRY; MALE; NONHUMAN; PLASMINOGEN ACTIVATION; SPERMATOZOON; ZONA PELLUCIDA;

MAMMALIA;

EID: 84863567156     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/des146     Document Type: Article

References (38)

1. Andreasen P, Egelund R, Petersen H. The plasminogen activation system in tumor growth, invasion, and metastasis. Cell Mol Life Sci 2000;57:25-40. (Pubitemid 30105328)
2. Austin CR, Braden AW. Polyspermy in mammals. Nature 1953;172:82-83.
3. Barros C, Yanagimachi R. Induction of zona reaction in golden hamster eggs by cortical granule material. Nature 1971;233:268-269.
4. Bedford JM. Enigmas of mammalian gamete form and function. Biol Rev Camb Phil Soc 2004;79:429-460. (Pubitemid 38691098)
5. Braden AW, Austin CR, David HA. The reaction of zona pellucida to sperm penetration. Aust J Biol Sci 1954;7:391-409.
6. Carmeliet P, Schoonjans L, Kieckens L, Ream B, Degen J, Bronson R, De Vos R, van den Oord JJ, Collen D, Mulligan RC. Physiological consequences of loss of plasminogen activator gene function in mice. Nature 1994;368:419-424. (Pubitemid 24115347)
7. Cherr GN, Drobnis EZ, Katz DF. Localization of cortical granule constituents before and after exocytosis in the hamster egg. J Exp Zool 1988;246:81-93.
8. Clark GF. Molecular models for mouse sperm-oocyte binding. Glycobiology 2011;21:3-5.
9. Collen D. Molecular mechanisms of fibrinolysis and their application to fibrin-specific thrombolytic therapy. J Cell Biochem 1987;33:77-86. (Pubitemid 17026374)
10. Coy P, Cánovas S, Mondéjar I, Saavedra MD, Romar R, Grullón L, Matás C, Avilés M. Oviduct-specific glycoprotein and heparin modulate sperm-zona pellucida interaction during fertilization and contribute to the control of polyspermy. Proc Natl Acad Sci USA 2008a;105:15809-15814.
11. Coy P, Grullón L, Cánovas S, Romar R, Matás C, Avilés M. Hardening of the zona pellucida of unfertilized eggs can reduce polyspermic fertilization in the pig and cow. Reproduction 2008b;135:19-27.
12. Ebisch I, Steegers-Theunissen R, Sweep F, Zielhuis G, Geurts-Moespot A, Thomas C. Possible role of the plasminogen activation system in human subfertility. Fertil Steril 2007;87:619-626. (Pubitemid 46385965)
13. Friberger P, Knö s M, Gustavsson S, Aurell L, Claeson G. Methods for determination of plasmin, antiplasmin and plasminogen by means of substrate S-2251. Haemostasis 1978;7:138-145. (Pubitemid 8360733)
14. Gahlay G, Gauthier L, Baibakov B, Epifano O, Dean J. Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein. Science 2010;329:216-219.
15. Gulyas BJ, Yuan LC. Cortical reaction and zona hardening in mouse oocytes following exposure to ethanol. J Exp Zool 1985;233:269-276. (Pubitemid 15125675)
16. Haley SA, Wessel GM. The cortical granule serine protease CGSP1 of the sea urchin, Strongylocentrotus purpuratus, is autocatalytic and contains a low-density lipoprotein receptor-like domain. Dev Biol 1999;211:1-10. (Pubitemid 29315816)
17. Hatcher MA, Starr JA. Role of tissue plasminogen activator in acute ischemic stroke. Ann Pharmacother 2011;45:364-371.
18. Hoodbhoy T, Talbot P. Mammalian cortical granules: contents, fate, and function. Mol Reprod Dev 1994;39:439-448. (Pubitemid 24382226)
19. Huarte J, Vassalli JD, Belin D, Sakkas D. Involvement of the plasminogen activator/plasmin proteolytic cascade in fertilization. Dev Biol 1993; 157:539-546. (Pubitemid 23191999)
20. Hunter RHF. Reflections upon sperm-endosalpingeal and sperm-zona pellucida interactions in vivo and in vitro. Reprod Domest Anim 2003; 38:147-154. (Pubitemid 36429628)
21. Kim TS, Sa SJ, Shin MY, Jang DM, Kwon SH, Kwon EH, Cho KH, Park CK, Lee DS. Stimulation of plasminogen activator activity by free radicals in boar spermatozoa. Anim Reprod Sci 2009;114:228-37.
22. Liu M. The biology and dynamics of mammalian cortical granules. Reprod Biol Endocrinol 2011;9:149.
23. Miller D, GongX, Decker G, Shur B. Egg cortical granuleN- acetylglucosaminidase is required for the mouse zona block to polyspermy. J Cell Biol 1993; 123:1431-1440. (Pubitemid 24012022)
24. Moller C, Wassarman P. Characterization of a proteinase that cleaves zona pellucida glycoprotein ZP2 following activation of mouse eggs. Dev Biol 1989;132:103-112. (Pubitemid 19071451)
25. Mondéjar I, Grullón LA, Garća-Vázquez FA, Romar R, Coy P. Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes. Fertil Steril 2012;97:453-461.
26. Pang PC, Chiu PC, Lee CL, Chang LY, Panico M, Morris HR, Haslam SM, Khoo KH, Clark GF, Yeung WS et al. Human sperm binding is mediated by the Sialyl-Lewisx oligosaccharide on the zona pellucida. Science 2011; 333:1761-1764.
27. Rekkas CA, Besenfelder U, Havlicek V, Vainas E, Brem G. Plasminogen activator activity in cortical granules of bovine oocytes during in vitro maturation. Theriogenology 2002;57:1897-1905. (Pubitemid 34517226)
28. Roldán-Olarte M, Jiménez-D́az M, Miceli DC. Plasminogen detection in oocytes and plasminogen activator activities in the porcine oviduct during the estrous cycle. Zygote 2005;13:115-123. (Pubitemid 41169609)
29. Sa SJ, Rhee HH, Cheong HT, Yang BK, Park CK. Effects of plasmin on sperm-oocyte interactions during in vitro fertilization in the pig. Anim Rep Sci 2006;95:273-282. (Pubitemid 44247350)
30. Saunders CM, Larman MG, Parrington J, Cox LJ, Royse J, Blayney LM, Swann K, Lai FA. PLC zeta: a sperm-specific trigger of Ca(2+) oscillations in eggs and embryo development. Development 2002; 129:533-544.
31. Schaller J, Gerber SS. The plasmin-antiplasmin system: structural and functional aspects. Cell Mol Life Sci 2011;68:785-801.
32. Smokovitis A, Kokolis N, Alexopolous C, Alexaki E, Eleftheriou E. Plasminogen activator activity, plasminogen activator inhibition and plasmin inhibition in spermatozoa and seminal plasma of man and various animal species, effect of plasmin on sperm motility. Fibrinolysis 1987;1:253-257.
33. Tutuncu L, Stein P, Ord T, Jorgez C, Williams C. Calreticulin on the mouse egg surface mediates transmembrane signaling linked to cell cycle resumption. Dev Biol 2004;270:246-260. (Pubitemid 38596941)
34. Wong JL, Wessel GM. Defending the zygote: search for the ancestral animal block to polyspermy. Curr Top Dev Biol 2006;72:1-151. (Pubitemid 43574747)
35. Yanagimachi R. Mammalian fertilization. In: Knobil E, Neil JD. (eds). The Physiology of Reproduction. New York: Raven Press, 1994.
36. Zervos IA, Lavrentiadou SN, Tsantarliotou MP, Georgiadis M, Kokolis NA, Taitzoglou IA. Seasonal variation of plasminogen activator activity in spermatozoa and seminal plasma of boar, buck, bull and stallion. Reprod Domest Anim 2010;45:440-446.
37. Zhang X, Rutledge J, Khamsi F, Armstrong D. Release of tissue-type plasminogen activator by activated rat eggs and its possible role in the zona reaction. Mol Reprod Dev 1992;32:28-32.
38. Zhang L, Seiffert D, Fowler BJ, Jenkins GR, Thinnes TC, Loskutoff DJ, Parmer RJ, Miles LA. Plasminogen has a broad extrahepatic distribution. Thromb Haemost 2002;87:493-501. (Pubitemid 34232492)