Intermediate and normal sized CGG repeat on the FMR1 gene does not negatively affect donor ovarian response

Human Reproduction

Volumn 27, Issue 7, 2012, Pages 2241-2242

  Gleicher, Norbert N ^a,b   Weghofer, Andrea ^a,c   Barad, David H ^a,b,d  

^a CENTER FOR HUMAN REPRODUCTION   (United States)

^b Foundation for Reproductive Medicine   (United States)

^c UNIVERSITY OF VIENNA   (Austria)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN; MUELLERIAN INHIBITING FACTOR;

CGG REPEAT; DONOR; GENE; GENE STRUCTURE; GENOTYPE; HUMAN; LETTER; OOCYTE; OVARIAN RESERVE; STIMULATION;

EID: 84863567075     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/des161     Document Type: Letter

References (10)

1. Gleicher N, Weghofer A, Barad DH. A pilot study of premature ovarian senescence: II. Different genotypes and phenotype for genetic and autoimmune etiologies. Fertil Steril 2009a;9:1707-1711.
2. Gleicher N, Weghofer A, Oktay K, Barad D. Relevance of triple CGG repeats in the FMR1 gene to ovarian reserve. Reprod Biomed Online 2009b;19:385-390.
3. Gleicher N, Weghofer A, Oktay K, Barad DH. Can the FMR1 (fragile X) gene serve a predictor of response to ovarian stimulation? Reprod Sci 2009c;16:462-467.
4. Gleicher N, Weghofer A, Oktay K, Barad DH. Correlation of triple repeats in the FMR1 (fragile X) gene to ovarian reserve: a new infertility test? Acta Obstet Gynecol Scand 2009d;88:1024-1030.
5. Gleicher N, Weghofer A, Barad DH. Ovarian reserve determinations suggest new function of FMR1 (fragile X gene) in regulating ovarian ageing. Reprod Biomed Online 2010a;20:768-775.
6. Gleicher N, Weghofer A, Lee IH, Barad DH. FMR1 genotype with autimmune-associated polycystic ovary-like phenotype and decreased pregnancy chances. PLoS ONE 2010b;5:315303.
7. Gleicher N, Weghofer A, Lee IH, Barad DH. Association of FMR1 genotypes with in vitro fertilization (IVF) outcomes based on ethnicity/race. PLoS ONE 2011;6:e18781.
8. Gleicher N, Weghofer A, Kim A, Barad DH. The impact in older women of ovarian FMR1 genotypes and sub-genotypes on ovarian reserve. PLoS ONE; 2012;7:e33638.
9. Lledo B, Guerrero J, Ortiz JA, Morales R, Ten J, Llacer J, Gimenez J, Bernabeu R. Itermediate and normal sized CGG repeats on the FMR1 gene does not negatively affect donor ovarian response. Hum Reprod 2012;27:609-614.
10. Weghofer A, Tea MK, Barad DH, Kim A, Singer CG, Wagner K, Gleicher N. BRCA1/2 are embryo lethal human gene mutations, rescued by low count (CGGn, 26)FMR1 mutations, suggesting CGG n, 26 as a new target for female cancer screening.