Inhibition of hypoxia and serum deprivation-induced apoptosis by salvianolic acid in rat mesenchymal stem cells

Journal of Traditional Chinese Medicine

Volumn 32, Issue 2, 2012, Pages 222-228

  Cao, Wei ^a   Guo, Xiao Wen ^b   Chen, Kai ^c   Xu, Rui Xia ^d   Zheng, Hu Zhan ^b   Wang, Jie ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c Chinese Medical University   (China)

^d PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; BMSCs; Hypoxia SD; SalB

Indexed keywords

CASPASE 3; SALVIANOLIC ACID B;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; FLOW CYTOMETRY; HEART MUSCLE; HYPOXIA; MESENCHYMAL STEM CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

EID: 84863564538     PISSN: 02552922     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0254-6272(13)60015-1     Document Type: Article

References (13)

1. Zhang M, Methot D, Poppa V, Fujio Y, Walsh K, Murry CE. Cardiomyocyte grafting for cardiac repair: graft cell death and anti death strategies. J Mol Cell Cardiol 2001; 33: 907-921
2. Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002; 105: 93-98
3. Zhu WQ, Chen JH, Cong XF, Hu SS, Chen X. Hypoxia and serum deprivation-induce apoptosis in mesenchymal stem cells. Stem Cells 2006; 24: 416-425
4. Xu RX, Chen X, Chen JH, Zhu WC, Han Y, Deng LZ, Cong XF. Experimental research into Lovastatin inhibiting apoptosis of rat BMSCs. China Journal of Senile Multi-organ Diseases 2009; 8: 259-264
5. Deng LZ, Chen X, Sang JL, Cong XF. The effect of glucocorticoid hormone on resisting apoptosis of rat BMSCs induced by hypoxia/SD. China J of Molecular Heart Disease 2009; 9: 84-87
6. Du GH, Zhang JT. Progress made in research into Sal, a water soluble effective ingredient of Danshen. Basic Medicine and Clinical Practice 2000; 20: 394
7. Jia N, Xiang HZ, Yang SS. Comment on progress made in research into Sal, a water soluble ingredient of Danshen. J of Liaoning TCM College 2006; 8: 41-42
8. Wang AH, Chen YJ, Liang YN. Progress made in research into the effect of Danshen on protecting cardiac muscles. Zhejiang J of Combination of TCM with Western Medicine 2006; 16: 724-726
9. Meng QN, Li GB, Geng XL, Guo MJ, Fan YC. Research into apoptosis of myocardial cells after SalB interfering in acute myocardial infarction of rats. J of Tianjin TCM University 2010; 29: 80-83
10. Jin HM, Zhao CM, Zhao X, Gan P, Luo YE, Liu B. Influence of SalB on expression of bcl-2 and bax protein of rats with local cerebral ischemia and re-perfusion. China J of TCM 2008; 26: 1475-1477
11. Scarabelli TM, Stephanou A, Pasini E, Gitti G, Townsend P, Lawrence K, Chen-Scarabelli C, Saravolatz L, Latchman D, Knight R, Gardin J. Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. J Am Coll Cardiol 2004; 43: 865-874
12. Nishikawa S, Tatsumi T, Shiraishi J, Matsunaga S, Takeda M, Mano A, Kobara M, Keira N, Okigaki M, Takahashi T, Matsubara H. Nicorandil regulates Bcl-2 family proteins and protects cardiac myocytes against hypoxia-induced apoptosis. J Mol Cell Cardiol 2006; 40: 510-519
13. Li RJ, Hao XR, Tang XY, Zhang ZY, Sun ZX, Zhang HS, Tong M. Influence of cyclopamine on human prostate cancer PC-3 cell proliferation and apoptosis as well as on expression of Bcl-2, Bax and Caspase-9 protein. Practical Clinical Medical Journal 2010; 14: 45