Ganoderma lucidum reduces kainic acid-induced hippocampal neuronal damage via inflammatory cytokines and glial fibrillary acid protein expression

Proceedings of the Western Pharmacology Society

Volumn 54, Issue , 2011, Pages 77-78

  Aguirre Moreno, A C ^a   Campos Pena V ^b   Villeda Hernandez J ^b   Leon Rivera I ^c   Montiel Arcos, E ^a  

^a UNIVERSIDAD AUTÓNOMA DEL ESTADO DE MORELOS   (Mexico)

^b NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^c CENTRO DE INVESTIGACIONES QUÍMICAS   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

GANODERMA LUCIDUM EXTRACT; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1BETA; KAINIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; EXCITOTOXICITY; GANODERMA LUCIDUM; HIPPOCAMPAL CA3 REGION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NERVE CELL LESION; NONHUMAN; PROTEIN EXPRESSION; RAT; SEIZURE;

EID: 84863562964     PISSN: 00838969     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Cao, L. Z., Lin, Z.B. (2003) Regulatory effect of Ganoderma lucidum polysaccharides on cytotoxic Tlymphocytes induced by dendritic cells in vitro. Acta Pharmacol. Sin. 24,321-326.
2. Hong, K.J., Dunn, D.M., Shen, C.L., Pence, B.C. (2004) Effects of Ganoderma lucidum on apoptotic and antiinflammatory function in HT-29 human colonic carcinoma cells. Phytother. Res. 18, 768-770. (Pubitemid 39481699)
3. You, Y.H., Lin, Z.B. (2002) Protective effects of Ganoderma lucidum polysaccharides peptide on injury of macrophages induced by reactive oxygen species. Acta Pharmacol Sin. 23, 787-791.
4. Kuo, M.C., Weng, C.Y., Ha, C.L., and Wu, M.J. (2006) Ganoderma lucidum mycelia enhance innate immunity by activating NF-kappa B. J. Ethnopharmacol. 103,217-222.
5. Sliva, D. (2004) Cellular and Physiological Effects of Ganoderma lucidum (Reishi) Mini Rev Med Chem. 4, 873-879.
6. Zhou, Z. Y., Tang, Y. P., Xiang, J., Wua, P., Jin, H. M., Wang, Z., Mori, M., Cai, D. F. (2010) Neuroprotective effects of water-soluble Ganoderma lucidum polysaccharides on cerebral ischemic injury in rats. J. Ethnopharmacol. 131,154-164.
7. Zhang, R., Xu, S., Cai, Y., Zhou, M., Zhou, X., Chap, P. (2009) Ganoderma lucidum Protects Dopaminergic Neuron Degeneration Through Inhibition of Microglial Activation. Evid. Based Complement. Alternat. Med.Jul 16. PMID: 19617199.
8. Zhao, H. B., Lin, S. Q., Liu, J. H., and Lin, Z. B. (2004) Polysaccharide Extract Isolated From Ganoderma lucidum Protects Rat Cerebral Cortical Neurons From Hypoxia/Reoxygenation Injury. J. Pharmacol. Sci. 95, 294-298.
9. Nadler, J.V., Perry, B.W., Gentry, C., Cotman, C.W. (1980). Degeneration of Hippocampal CA3 pyramidal cells induced by intraventricular kaínico acid, J. Comp. Neurol. 192, 333-359. (Pubitemid 10035307)
10. Ben-Ari, Y. and Cossart, R. (2000) Kainate, a double agent that generates seizures: two decades of progress. Trends Neurosci. 23, 580-587