Establishment of a canine model of human type 2 diabetes mellitus by overexpressing phosphoenolypyruvate carboxykinase

International Journal of Molecular Medicine

Volumn 30, Issue 2, 2012, Pages 321-329

  Jeong, Yeon Woo ^a   Lee, Geun Shik ^b   Kim, Joung Joo ^a   Park, Sun Woo ^a   Ko, Kyeong Hee ^a   Kang, Mina ^a   Kim, Yu Kyung ^a   Jung, Eui Man ^c   Hyun, Sang Hwan ^c   Shin, Taeyoung ^a   Jeung, Eui Bae ^c   Hwang, Woo Suk ^a  

^a Sooam Biotech Research Foundation   (South Korea)

^b Kangwon National University   (South Korea)

^c Chungbuk National University   (South Korea)

Author keywords

Canine disease model; Phosphoenolpyruvate carboxykinase; Somatic cell nuclear transfer; Transgenic dogs; Type 2 diabetes mellitus

Indexed keywords

LIVER PROTEIN; MESSENGER RNA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CLONING; CELL FUSION; CONTROLLED STUDY; EXPERIMENTAL DOG; FEMALE; FETUS; FIBROBLAST; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL LINE; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DOGS; EMBRYO TRANSFER; FEMALE; FIBROBLASTS; GENE EXPRESSION; GENE ORDER; GENE TARGETING; GENETIC VECTORS; HUMANS; NUCLEAR TRANSFER TECHNIQUES; PROMOTER REGIONS, GENETIC; PROTEIN-SERINE-THREONINE KINASES;

EID: 84863552877     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.993     Document Type: Article

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