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Volumn 26, Issue 4, 2012, Pages 538-542

Virological response to darunavir in patients infected with HIV is linked to darunavir resistance-associated mutations corrected by the count of mutations with positive impact and is not associated with pharmacological and combined virological/pharmacological parameters

Author keywords

Darunavir; Genotypic inhibitory quotient; Human immunodeficiency virus

Indexed keywords

DARUNAVIR; DARUNAVIR PLUS RITONAVIR; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; RALTEGRAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 84863550558     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2011.00949.x     Document Type: Article
Times cited : (3)

References (10)
  • 1
    • 64649102226 scopus 로고    scopus 로고
    • Darunavir: a review of its use in the management of HIV infection in adults
    • McKeage K., Perry C.M., Keam S.J. Darunavir: a review of its use in the management of HIV infection in adults. Drugs (2009) 69 477-503.
    • (2009) Drugs , vol.69 , pp. 477-503
    • McKeage, K.1    Perry, C.M.2    Keam, S.J.3
  • 2
    • 42049102201 scopus 로고    scopus 로고
    • Inhibitory quotient in HIV pharmacology
    • La Porte C. Inhibitory quotient in HIV pharmacology. Curr. Opin. HIV AIDS (2008) 3 283-287.
    • (2008) Curr. Opin. HIV AIDS , vol.3 , pp. 283-287
    • La Porte, C.1
  • 3
    • 55849125465 scopus 로고    scopus 로고
    • Darunavir inhibitory quotient predicts the 48-week virological response to darunavir-based salvage therapy in human immunodeficiency virus-infected protease inhibitor-experienced patients
    • Moltó J., Santos J.R., Pérez-Alvarez N. et al. Darunavir inhibitory quotient predicts the 48-week virological response to darunavir-based salvage therapy in human immunodeficiency virus-infected protease inhibitor-experienced patients. Antimicrob. Agents Chemother. (2008) 52 3928-3932.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 3928-3932
    • Moltó, J.1    Santos, J.R.2    Pérez-Alvarez, N.3
  • 4
    • 42149135585 scopus 로고    scopus 로고
    • Virological response to darunavir/ritonavir-based regimens in antiretroviral-experienced patients (PREDIZISTA study)
    • Pellegrin I., Wittkop L., Joubert L.M. et al. Virological response to darunavir/ritonavir-based regimens in antiretroviral-experienced patients (PREDIZISTA study). Antivir. Ther. (2008) 13 271-279.
    • (2008) Antivir. Ther. , vol.13 , pp. 271-279
    • Pellegrin, I.1    Wittkop, L.2    Joubert, L.M.3
  • 5
    • 76449109384 scopus 로고    scopus 로고
    • Factors predictive of successful darunavir/ritonavir-based therapy in highly antiretroviral-experienced HIV-1-infected patients (the DARWEST study)
    • Delaugerre C., Buyck J.F., Peytavin G. et al. Factors predictive of successful darunavir/ritonavir-based therapy in highly antiretroviral-experienced HIV-1-infected patients (the DARWEST study). J. Clin. Virol. (2010) 47 248-252.
    • (2010) J. Clin. Virol. , vol.47 , pp. 248-252
    • Delaugerre, C.1    Buyck, J.F.2    Peytavin, G.3
  • 6
    • 84873983398 scopus 로고    scopus 로고
    • Confirmation of the negative impact of protease mutations I47V, I54M, T74P and I84V and the positive impact of protease mutation V82A on virological response to darunavir/ritonavir. 17th International HIV drug resistance workshop: basic principles and clinical implications. 9-13 June 2009, Fort Myers, Florida, USA. Abstract 126.
    • De Meyer S., Descamps D., Van Baelen B. et al. Confirmation of the negative impact of protease mutations I47V, I54M, T74P and I84V and the positive impact of protease mutation V82A on virological response to darunavir/ritonavir. 17th International HIV drug resistance workshop: basic principles and clinical implications. 9-13 June 2009, Fort Myers, Florida, USA. Abstract 126.
    • De Meyer, S.1    Descamps, D.2    Van Baelen, B.3
  • 7
    • 60749130473 scopus 로고    scopus 로고
    • Mutations associated with virological response to darunavir/ritonavir in HIV-1-infected protease inhibitor-experienced patients
    • Descamps D., Lambert-Niclot S., Marcelin A.G. et al. Mutations associated with virological response to darunavir/ritonavir in HIV-1-infected protease inhibitor-experienced patients. J. Antimicrob. Chemother. (2009) 63 585-592.
    • (2009) J. Antimicrob. Chemother. , vol.63 , pp. 585-592
    • Descamps, D.1    Lambert-Niclot, S.2    Marcelin, A.G.3
  • 8
    • 69749092716 scopus 로고    scopus 로고
    • A liquid chromatography-tandem mass spectrometry assay for quantification of nevirapine, indinavir, atazanavir, amprenavir, saquinavir, ritonavir, lopinavir, efavirenz, tipranavir, darunavir and maraviroc in the plasma of patients infected with HIV
    • Martin J., Deslandes G., Dailly E. et al. A liquid chromatography-tandem mass spectrometry assay for quantification of nevirapine, indinavir, atazanavir, amprenavir, saquinavir, ritonavir, lopinavir, efavirenz, tipranavir, darunavir and maraviroc in the plasma of patients infected with HIV. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2009) 877 3072-3082.
    • (2009) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , vol.877 , pp. 3072-3082
    • Martin, J.1    Deslandes, G.2    Dailly, E.3
  • 9
    • 84873981722 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic (PK/PD) analyses of darunavir in the TITAN study. 11th European AIDS conference, 24-27 October 2007, Madrid, Spain. Abstract P4.1/10.
    • Sekar V., De Paepa E., Van Baelen B. et al. Pharmacokinetic/pharmacodynamic (PK/PD) analyses of darunavir in the TITAN study. 11th European AIDS conference, 24-27 October 2007, Madrid, Spain. Abstract P4.1/10.
    • Sekar, V.1    De Paepa, E.2    Van Baelen, B.3
  • 10
    • 41449098109 scopus 로고    scopus 로고
    • Resistance profile of darunavir: combined 24-week results from the POWER trials
    • de Meyer S., Vangeneugden T., van Baelen B. et al. Resistance profile of darunavir: combined 24-week results from the POWER trials. AIDS Res. Hum. Retroviruses (2008) 24 379-388.
    • (2008) AIDS Res. Hum. Retroviruses , vol.24 , pp. 379-388
    • de Meyer, S.1    Vangeneugden, T.2    van Baelen, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.