Association Between Multiple Sclerosis and Erectile Dysfunction: A Nationwide Case-Control Study

Journal of Sexual Medicine

Volumn 9, Issue 7, 2012, Pages 1753-1759

  Keller, Joseph J ^a   Liang, Yu Chih ^a   Lin, Herng Ching ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Epidemiology; Erectile dysfunction; Multiple sclerosis; Neurologic disorder and sexual dysfunction

Indexed keywords

ADULT; AGED; ALCOHOL ABUSE; ALCOHOLISM; ARTICLE; CASE CONTROL STUDY; COMORBIDITY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE REGISTRY; ERECTILE DYSFUNCTION; HEALTH CARE COST; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; INCIDENCE; INTERNATIONAL CLASSIFICATION OF DISEASES; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; OBESITY; PRIORITY JOURNAL; RISK ASSESSMENT; TAIWAN;

EID: 84863524992     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2012.02746.x     Document Type: Article

References (37)

1. Kuroiwa Y, Hung TP, Landsborough D, Park CS, Singhal BS. Multiple sclerosis in Asia. Neurology 1977;27:188-92.
2. Kuroiwa Y, Igata A, Itahara K, Koshijima S, Tsubaki T. Nationwide survey of multiple sclerosis in Japan: Clinical analysis of 1, 084 cases. Neurology 1975;25:845-51.
3. Pugliatti M, Rosati G, Carton H, Riise T, Drulovic J, Vécsei L, Milanov I. The epidemiology of multiple sclerosis in Europe. Eur J Neurol 2006;13:700-22.
4. Cheng Q, Cheng XJ, Jiang GX. Multiple sclerosis in China-History and future. Mult Scler 2009;15:655-60.
5. Rotstein Z, Hazan R, Barak Y, Achiron A. Perspectives in multiple sclerosis health care: Special focus on the costs of multiple sclerosis. Autoimmun Rev 2006;5:511-6.
6. Compston A, Coles A. Multiple sclerosis. Lancet 2008;372:1502-17.
7. Donzé C, Hautecoeur P. Urinary, sexual, and bowel disorders in early-stage multiple sclerosis. Rev Neurol (Paris) 2009;165:S148-55.
8. Schmidt EZ, Hofmann P, Niederwieser G, Kapfhammer HP, Bonelli RM. Sexuality in multiple sclerosis. J Neural Transm 2005;112:1201-11.
9. Lombardi G, Celso M, Bartelli M, Cilotti A, Del Popolo G. Female sexual dysfunction and hormonal status in multiple sclerosis patients. J Sex Med 2011;8:1138-46.
10. Kessler TM, Fowler CJ, Panicker JN. Sexual dysfunction in multiple sclerosis. Expert Rev Neurother 2009;9:341-50.
11. Nicolosi A, Laumann E, Glasser D, Moreira E, Paik A, Gingell C. Sexual behavior and sexual dysfunctions after age 40: The global study of sexual attitudes and behaviours. Urology 2004;64:991-54.
12. Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IEEF): A multidimensional scale for assessment of erectile dysfunction. Urology 1997;49:822-30.
13. Lilius HG, Valtonen EJ, Wikstrom J. Sexual problems in patients suffering from multiple sclerosis. Scand J Soc Med 1976;4:41-4.
14. Mattson D, Petrie M, Srivastava DK, McDermott M. Multiple sclerosis. Sexual dysfunction and its response to medications. Arch Neurol 1995;52:862-8.
15. Valleroy ML, Kraft GH. Sexual dysfunction in multiple sclerosis. Arch Phys Med Rehabil 1984;65:125-8.
16. Jonsson A. Disseminated sclerosis and sexuality. Ugeskr Laeger 2003;165:2642-6.
17. McCabe M, McDonald E, Deeks A, Vowels L, Cobain M. The impact of multiple sclerosis on sexuality and relationships. J Sex Res 1996;33:241-4.
18. Lewis RW, Fugl-Meyer KS, Corona G, Hayes RD, Laumann EO, Moreira ED Jr, Rellini AH, Segraves T. Definitions/epidemiology/risk factors for sexual dysfunction. J Sex Med 2010;7:1598-607.
19. Corona G, Lee DM, Forti G, O'Connor DB, Maggi M, O'Neill TW, Pendleton N, Bartfai G, Boonen S, Casanueva FF, Finn JD, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Punab M, Silman AJ, Vanderschueren D, Wu FC; EMAS Study Group. Age-related changes in general and sexual health in middle-aged and older men: Results from the European Male Ageing Study (EMAS). J Sex Med 2010;7:1362-80.
20. Johannes CB, Araujo AB, Feldman HA, Derby CA, Kleinman KP, McKinlay JB. Incidence of erectile dysfunction in men 40 to 69 years old: Longitudinal results from the Massachusetts male aging study. J Urol 2000;163:460-3.
21. O'Leary MP, Althof SE, Cappelleri JC, Crowley A, Sherman N, Duttagupta S. Self-esteem, confidence and relationship satisfaction of men with erectile dysfunction treated with sildenafil citrate: A multicenter, randomized, parallel group, double blind, placebo controlled study in the United States. J Urol 2006;175:1058-62.
22. Lin HC, Chao PZ, Lee HC. Sudden sensorineural hearing loss increases the risk of stroke: A 5-year follow-up study. Stroke 2008;39:2744-8.
23. Zivadinov R, Zorzon M, Bosco A, Bragadin LM, Moretti R, Bonfigli L, Iona LG, Cazzato G. Sexual dysfunction in multiple sclerosis: II. Correlation analysis. Mult Scler 1999;5:418-27.
24. Vlachopoulos C, Rokkas K, Ioakeimidis N, Stefanadis C. Inflammation, metabolic syndrome, erectile dysfunction, and coronary artery disease: Common links. Eur Urol 2007;52:1590-600.
25. Lundberg PO, Brackett NL, Denys P, Chartier-Kastler E, Sønksen J, Vodusek DB. Neurological disorders: Erectile and ejaculatory dysfunction. In: Jardin A, Wagner G, Khoury S, Giuliano S, Padma-Nathan H, Rosen R, eds. Erectile dysfunction. London: Health Publication; 1999:591-649.
26. Kaufman JM, Deslypere JP, Giri M, Vermeulen A. Neuroendocrine regulation of pulsatile luteinizing hormone secretion in elderly men. J Steroid Biochem Mol Biol 1990;37:421-30.
27. Kaiser DR, Billups K, Mason C, Wetterling R, Lundberg JL, Bank AJ. Impaired brachial artery endothelium-dependent and -independent vasodilation in men with erectile dysfunction and no other clinical cardiovascular disease. J Am Coll Cardiol 2004;43:179-84.
28. Trepels T, Zeiher A, Fichtlscherer S. The endothelium and inflammation. Endothelium 2006;13:423-9.
29. Verma S, Wang CH, Li SH, Dumont AS, Fedak PW, Badiwala MV. A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation 2002;106:913-9.
30. Yavuzgil O, Altay B, Zoghi M, Gürgün C, Kayikçioǧlu M, Kültürsay H. Endothelial function in patients with vasculogenic erectile dysfunction. Int J Cardiol 2005;103:19-26.
31. Esper RJ, Nordaby RA, Vilariño JO, Paragano A, Cacharrón JL, Machado RA. Endothelial dysfunction: A comprehensive appraisal. Cardiovasc Diabetol 2006;23:5-8.
32. Azadzoi K, Saenz de Tejada I. Hypercholesterolemia impairs endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle. J Urol 1991;146:238-40.
33. Lin HC, Xirasagar S, Chen CH, Hwang YT. Physician's case volume of intensive care unit pneumonia admissions and in-hospital mortality. Am J Respir Crit Care Med 2008;177:989-94.
34. Demirkiran M, Sarica Y, Uguz S, Yerdelen D, Aslan K. Multiple sclerosis patients with and without sexual dysfunction: Are there any differences? Mult Scler 2006;12:209-14.
35. DasGupta R, Fowler CJ. Bladder, bowel and sexual dysfunction in multiple sclerosis: Management strategies. Drugs 2003;63:153-66.
36. Lombardi G, Macchiarella A, Del Popolo G. Efficacy and safety of tadalafil for erectile dysfunction in patients with multiple sclerosis. J Sex Med 2010;7:2192-200.
37. Zhang HL, Pan W, Wu J. Efficacy and safety of tadalafil for erectile dysfunction in patients with multiple sclerosis. J Sex Med 2011;8:1257-8.