Nanoparticle penetration through filter media and leakage through face seal interface of n95 filtering facepiece respirators

Annals of Occupational Hygiene

Volumn 56, Issue 5, 2012, Pages 568-580

  Rengasamy, Samy ^a   Eimer, Benjamin C ^b  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b Policy and Standard Development Branch ^*  (United States)

Author keywords

Face seal leakage; Filter penetration; N95 filtering facepiece respirator; Nanoparticles; Total inward leakage

Indexed keywords

BREATHING ZONES; COMPONENT INTERFACES; DIFFERENT SIZES; ELECTROSTATIC CHARGES; FACE SEALS; FILTER EFFICIENCY; FILTER MEDIA; FILTER PENETRATION; FILTERING FACEPIECE; HIGH CONCENTRATION; HOLE SIZE; INFORMATION CONCERNING; MECHANICAL FILTERS; NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTHS; PARTICLE LEAKAGE; PARTICLE PENETRATION; PENETRATION VALUES;

ATMOSPHERIC AEROSOLS; ELECTROSTATICS; FILTERS (FOR FLUIDS); NANOPARTICLES; SEALS;

RESPIRATORS;

NANOPARTICLE;

AEROSOL; AIR POLLUTANT; AUDIOVISUAL EQUIPMENT; BIOLOGICAL MODEL; BREATHING RATE; CONFERENCE PAPER; EQUIPMENT DESIGN; EXPOSURE; FACE; FILTRATION; GAS MASK; HUMAN; INSTRUMENTATION; MATERIALS TESTING; METHODOLOGY; OCCUPATIONAL HEALTH SERVICE; PARTICLE SIZE; STANDARD; STATISTICS; UNITED STATES;

AEROSOLS; AIR POLLUTANTS, OCCUPATIONAL; EQUIPMENT DESIGN; FACE; FILTRATION; HUMANS; INHALATION EXPOSURE; MANIKINS; MATERIALS TESTING; MODELS, BIOLOGICAL; NANOPARTICLES; NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH (U.S.); PARTICLE SIZE; RESPIRATORY PROTECTIVE DEVICES; RESPIRATORY RATE; UNITED STATES;

EID: 84863522674     PISSN: 00034878     EISSN: 14753162     Source Type: Journal    
DOI: 10.1093/annhyg/mer122     Document Type: Conference Paper

References (34)

1. Aitken RJ, Creely KS, Tran CL. (2004) Nanoparticles: an occupational hygiene review. Edinburgh, UK: Institute of occupational Medicine.
2. Balazy A, Toivola M, Reponen T et al. (2006) Manikin-based performance evaluation of N95 filtering-facepiece respirators challenged with nanoparticles. Ann Occup Hyg; 50: 259-69.
3. Bello D, Wardle BL, Yamamoto N et al. (2009) Exposure to nanoscale particles and fibers during machining of hybrid advanced composites containing carbon nanotubes. J Nanopart Res; 11: 231-49.
4. Brooks RD, Rajagopalan S, Pope I et al. (2010) Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association. Circulation; 121: 2331-78.
5. Byrne JD, Baugh JA. (2008) The significance of nanoparticles in particle-induced pulmonary fibrosis. McGill J Med; 11: 43-50. (Pubitemid 351428241)
6. Chen CC, Huang SH. (1998) The effects of particle charge on the performance of a filtering facepiece. Am Ind Hyg Assoc J; 59: 227-33.
7. Chen CC, Willeke K. (1992) Characteristics of face seal leakage in filtering facepieces. Am Ind Hyg Assoc J; 53: 533-9.
8. Coffey CC, Zhuang Z, Campbell DL et al. (1998) Quantitative fit-testing of N95 respirators: part II-results, effect of filter penetration, fit-test, and pass/fail criteria on respirator performance. J Int Soc Res Prot (Spring-Winter); 25-36.
9. Eninger RM, Honda T, Adhikari A et al. (2008) Filter performance of N99 and N95 facepiece respirators against viruses and ultrafine particles. Ann Occup Hyg; 52: 385-96. (Pubitemid 351989647)
10. Grinshpun S, Haruta H, Eninger RM et al. (2009) Performance of an N95 filtering facepiece particulate respirator and a surgical mask during human breathing: two pathways for particle penetration. J Occup Environ Hyg; 6: 593-603.
11. Han DH, Lee J. (2005) Evaluation of particulate filtering respirators using inward leakage (IL) or total inward leakage (TIL) testing-Korean experience. Ann Occup Hyg; 49: 569-74. (Pubitemid 41442682)
12. Haruta H, Honda T, Eninger RM et al. (2008) Experimental and theoretical investigation of the performance of N95 respirator filters against ultrafine aerosols. J Int Soc Res Prot; 25: 75-88.
13. Hinds WC. (1999) Properties, behavior, and measurement of airborne particles. New York, NY: Wiley-Interscience Publication; John Wiley & Sons, Inc.
14. Hinds WC, Kraske G. (1987) Performance of dust respirators with facial seal leaks: I. Experimental. Am Ind Hyg Assoc J; 48: 836-41. (Pubitemid 17140729)
15. Holton PM, Tackett DL, Willeke K. (1987) Particle sizedependent leakage and losses of aerosols in respirators. Am Ind Hyg Assoc J; 48: 848-54. (Pubitemid 17140731)
16. Huang S-H, Chen C-W, Chang C-P et al. (2007) Penetration of 4.5 nm to 10 lm aerosol particles through fibrous filters. J Aerosol Sci; 38: 719-27. (Pubitemid 47096644)
17. ISO/TS. (2009) Nanotechnologies-terminology and definitions for nano-objects-nanoparticle, nanofibre and nanoplate. Geneva, Switzerland: International Standards Organization.
18. Janssen LL, Weber R. (2005) Effect of pressure drop on respirator face seal leakage. J Occup Environ Hyg; 2: 335-40. (Pubitemid 40973801)
19. Johnson DR, Methner MM, Kennedy AJ et al. (2010) Potential for occupational exposure to engineered carbon-based nanomaterials in environmental laboratory studies. Environ Health Perspect; 118: 49-54.
20. Krishnan U, Willeke K, Juozaitis A et al. (1994) Variation in quantitative respirator fit factors due to fluctuations in leak size during fit testing. Am Ind Hyg Assoc J; 55: 309-14. (Pubitemid 24109082)
21. Lee S-A, Grinshpun SA, Reponen T. (2008) Respiratory performance offered by N95 respirators and surgical masks: human subject evaluation with NaCl aerosol representing bacterial and viral particle size range. Ann Occup Hyg; 3: 177-85.
22. Liu BYH, Lee J-K, Mullins H et al. (1993) Respirator leak detection by ultrafine aerosols: a predictive model and experimental study. Aerosol Sci Tech; 19: 15-26. (Pubitemid 23180434)
23. Martin SB Jr, Moyer ES. (2000) Electrostatic respirator filter media: filter efficiency and most penetrating particle size effects. Appl Occup Environ Hyg; 15: 609-17. (Pubitemid 30641906)
24. Myers WR, Zhuang Z, Nelson T et al. (1995) Field performance measurements of half-facepiece respirators-study protocol. Am Ind Hyg Assoc J; 56: 765-75.
25. NIOSH. (1995) Respiratory protection devices. Title 42, Code of Federal regulation, Part 84. Washington, DC: U.S. Government Printing Office, Office of the Federal Register; pp. 30335-98.
26. Qian Y, Willeke K, Grinshpun SA et al. (1998) Performance of N95 respirators: filtration efficiency for airborne microbial and inert particles. Am Ind Hyg Assoc J; 59: 128-32.
27. Rengasamy S, Eimer B. (2011) Total inward leakage of nanoparticles through filtering facepiece respirators. Ann Occup Hyg; 55: 253-63.
28. Rengasamy S, Eimer B, Shaffer RE. (2009) Comparison of nanoparticle filtration performance of NIOSH-approved and CE marked filtering-facepiece respirators. Ann Occup Hyg; 53: 117-28.
29. Rengasamy S, King WP, Eimer B et al. (2008) Filtration performance of NIOSH-approved N95 and P100 filtering-facepiece respirators against 4-30 nanometer size nanoparticles. J Occup Environ Hyg; 5: 556-64.
30. Rengasamy S, Verbofsky R, King WP et al. (2007) Nanoparticle penetration through NIOSH-approved N95 filteringfacepiece respirators. J Int Soc Res Prot; 24: 49-59.
31. Reponen T, Lee S-A, Grinshpun SA et al. (2011) Effect of fit testing on the protection offered by N95 filtering facepiece respirators against fine particles in a laboratory setting. Ann Occup Hyg; 55: 264-71.
32. Seaton A, Tran L, Aitken R et al. (2009) Nanoparticles, human health hazard and regulation. J Royal Soc Interface; doi: 10.1098/rsif.2009.0252.focus.
33. Shvedova AA, Kisin ER, Porter D et al. (2009) Mechanism of pulmonary toxicity and medical applications of carbon nanotubes: two faces of Janus? Pharmacol Ther; 121: 192-204.
34. Zhuang Z, Coffey CC, Jensen PA et al. (2003) Correlation between quantitative fit factors and workplace PFs measured in actual workplace environments at a steel foundry. Am Ind Hyg Assoc J; 64: 730-38. (Pubitemid 37541852)