-
1
-
-
55949086924
-
Hepatocellular carcinoma: epidemiology, risk factors and pathogenesis
-
Gomaa AI, Khan SA, Toledano MB, Waked I, Taylor-Robinson SD. Hepatocellular carcinoma: epidemiology, risk factors and pathogenesis. World J Gastroenterol 2008; 14: 4300-8.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 4300-4308
-
-
Gomaa, A.I.1
Khan, S.A.2
Toledano, M.B.3
Waked, I.4
Taylor-Robinson, S.D.5
-
2
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: from genes to environment
-
Farazi PA, Depinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev 2006; 6: 674-87.
-
(2006)
Nat Rev
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
Depinho, R.A.2
-
3
-
-
7044229778
-
Primary liver cancer: worldwide incidence and trends
-
Bosch FX, Ribes J, Diaz M, Cleries R. Primary liver cancer: worldwide incidence and trends. Gastroenterology 2004; 127(5 Suppl. 1): S5-16.
-
(2004)
Gastroenterology
, vol.127
, Issue.5 SUPPL. 1
-
-
Bosch, F.X.1
Ribes, J.2
Diaz, M.3
Cleries, R.4
-
4
-
-
33646337650
-
Hepatocellular carcinoma and hepatitis B virus
-
Chan HL, Sung JJ. Hepatocellular carcinoma and hepatitis B virus. Semin Liver Dis 2006; 26: 153-61.
-
(2006)
Semin Liver Dis
, vol.26
, pp. 153-161
-
-
Chan, H.L.1
Sung, J.J.2
-
5
-
-
17244382334
-
How to predict HCC development in patients with chronic B viral liver disease?
-
Han KH, Ahn SH. How to predict HCC development in patients with chronic B viral liver disease? Intervirology 2005; 48: 23-8.
-
(2005)
Intervirology
, vol.48
, pp. 23-28
-
-
Han, K.H.1
Ahn, S.H.2
-
6
-
-
58149376548
-
Molecular mechanisms of hepatocellular carcinoma
-
Aravalli RN, Steer CJ, Cressman EN. Molecular mechanisms of hepatocellular carcinoma. Hepatology 2008; 48: 2047-63.
-
(2008)
Hepatology
, vol.48
, pp. 2047-2063
-
-
Aravalli, R.N.1
Steer, C.J.2
Cressman, E.N.3
-
7
-
-
0036828752
-
Interaction of hepatitis B virus, chemical carcinogen, and genetic susceptibility: multistage hepatocarcinogenesis with multifactorial etiology
-
Chen CJ, Chen DS. Interaction of hepatitis B virus, chemical carcinogen, and genetic susceptibility: multistage hepatocarcinogenesis with multifactorial etiology. Hepatology 2002; 36: 1046-9.
-
(2002)
Hepatology
, vol.36
, pp. 1046-1049
-
-
Chen, C.J.1
Chen, D.S.2
-
8
-
-
0036841865
-
Hepatocellular carcinoma: the high-risk patient
-
Nissen NN, Martin P. Hepatocellular carcinoma: the high-risk patient. J Clin Gastroenterol 2002; 35(5 Suppl. 2): S79-85.
-
(2002)
J Clin Gastroenterol
, vol.35
, Issue.5 SUPPL. 2
-
-
Nissen, N.N.1
Martin, P.2
-
9
-
-
18344377030
-
The p53 pathway: positive and negative feedback loops
-
Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene 2005; 24: 2899-908.
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
10
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997; 387: 296-9.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
12
-
-
0035211073
-
The p53 functional circuit
-
Jin S, Levine AJ. The p53 functional circuit. J Cell Sci 2001; 114(Part 23): 4139-40.
-
(2001)
J Cell Sci
, vol.114
, Issue.PART 23
, pp. 4139-4140
-
-
Jin, S.1
Levine, A.J.2
-
13
-
-
0037329056
-
The p53-Mdm2 module and the ubiquitin system
-
Michael D, Oren M. The p53-Mdm2 module and the ubiquitin system. Semin Cancer Biol 2003; 13: 49-58.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 49-58
-
-
Michael, D.1
Oren, M.2
-
14
-
-
0032417695
-
Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
-
Jones SN, Hancock AR, Vogel H, Donehower LA, Bradley A. Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis. Proc Nat Acad Sci USA 1998; 95: 15608-12.
-
(1998)
Proc Nat Acad Sci USA
, vol.95
, pp. 15608-15612
-
-
Jones, S.N.1
Hancock, A.R.2
Vogel, H.3
Donehower, L.A.4
Bradley, A.5
-
15
-
-
0034086242
-
Protein expression of MDM2 and its clinicopathological relationships in human hepatocellular carcinoma
-
Endo K, Ueda T, Ohta T, Terada T. Protein expression of MDM2 and its clinicopathological relationships in human hepatocellular carcinoma. Liver 2000; 20: 209-15.
-
(2000)
Liver
, vol.20
, pp. 209-215
-
-
Endo, K.1
Ueda, T.2
Ohta, T.3
Terada, T.4
-
16
-
-
14544281476
-
Hepatocellular carcinoma-survival and clinical characteristics in relation to various histologic molecular markers in Western patients
-
Schoniger-Hekele M, Hanel S, Wrba F, Muller C. Hepatocellular carcinoma-survival and clinical characteristics in relation to various histologic molecular markers in Western patients. Liver Int 2005; 25: 62-9.
-
(2005)
Liver Int
, vol.25
, pp. 62-69
-
-
Schoniger-Hekele, M.1
Hanel, S.2
Wrba, F.3
Muller, C.4
-
17
-
-
8844278362
-
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
-
Bond GL, Hu W, Bond EE, et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 2004; 119: 591-602.
-
(2004)
Cell
, vol.119
, pp. 591-602
-
-
Bond, G.L.1
Hu, W.2
Bond, E.E.3
-
18
-
-
29944441900
-
Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer
-
Zhang X, Miao X, Guo Y, et al. Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Hum Mutat 2006; 27: 110-7.
-
(2006)
Hum Mutat
, vol.27
, pp. 110-117
-
-
Zhang, X.1
Miao, X.2
Guo, Y.3
-
19
-
-
84655160759
-
MDM2 309 T/G polymorphism is associated with colorectal cancer risk especially in Asians: a meta-analysis
-
London, England: Northwood
-
Fang F, Yu XJ, Yu L, Yao L. MDM2 309 T/G polymorphism is associated with colorectal cancer risk especially in Asians: a meta-analysis. Medical Oncology. London, England: Northwood, 2010.
-
(2010)
Medical Oncology
-
-
Fang, F.1
Yu, X.J.2
Yu, L.3
Yao, L.4
-
20
-
-
33749546905
-
MDM2 gene promoter polymorphisms and risk of lung cancer: a case-control analysis
-
Li G, Zhai X, Zhang Z, et al. MDM2 gene promoter polymorphisms and risk of lung cancer: a case-control analysis. Carcinogenesis 2006; 27: 2028-33.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2028-2033
-
-
Li, G.1
Zhai, X.2
Zhang, Z.3
-
21
-
-
33746239400
-
Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population
-
Ma H, Hu Z, Zhai X, et al. Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population. Cancer Lett 2006; 240: 261-7.
-
(2006)
Cancer Lett
, vol.240
, pp. 261-267
-
-
Ma, H.1
Hu, Z.2
Zhai, X.3
-
22
-
-
33749040649
-
MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis
-
Ohmiya N, Taguchi A, Mabuchi N, et al. MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. J Clin Oncol 2006; 24: 4434-40.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4434-4440
-
-
Ohmiya, N.1
Taguchi, A.2
Mabuchi, N.3
-
23
-
-
33750690647
-
MDM2 T309G polymorphism is associated with bladder cancer
-
Onat OE, Tez M, Ozcelik T, Toruner GA. MDM2 T309G polymorphism is associated with bladder cancer. Anticancer Res 2006; 26: 3473-5.
-
(2006)
Anticancer Res
, vol.26
, pp. 3473-3475
-
-
Onat, O.E.1
Tez, M.2
Ozcelik, T.3
Toruner, G.A.4
-
24
-
-
77955680497
-
MDM2 promoter polymorphism is associated with increased susceptibility to hepatocellular carcinoma in Turkish population
-
Akkiz H, Sumbul AT, Bayram S, Bekar A, Akgollu E. MDM2 promoter polymorphism is associated with increased susceptibility to hepatocellular carcinoma in Turkish population. Cancer epidemiology 2010; 34: 448-52.
-
(2010)
Cancer epidemiology
, vol.34
, pp. 448-452
-
-
Akkiz, H.1
Sumbul, A.T.2
Bayram, S.3
Bekar, A.4
Akgollu, E.5
-
25
-
-
33748344945
-
MDM2 promoter SNP309 is associated with the risk of hepatocellular carcinoma in patients with chronic hepatitis C
-
Dharel N, Kato N, Muroyama R, et al. MDM2 promoter SNP309 is associated with the risk of hepatocellular carcinoma in patients with chronic hepatitis C. Clin Cancer Res 2006; 12: 4867-71.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4867-4871
-
-
Dharel, N.1
Kato, N.2
Muroyama, R.3
-
26
-
-
67349151299
-
MDM2 SNP309T>G polymorphism and risk of hepatocellular carcinoma: a case-control analysis in a Moroccan population
-
Ezzikouri S, El Feydi AE, Afifi R, et al. MDM2 SNP309T>G polymorphism and risk of hepatocellular carcinoma: a case-control analysis in a Moroccan population. Cancer Detect Prev 2009; 32: 380-5.
-
(2009)
Cancer Detect Prev
, vol.32
, pp. 380-385
-
-
Ezzikouri, S.1
El Feydi, A.E.2
Afifi, R.3
-
27
-
-
74049144962
-
Association between MDM2-SNP309 and hepatocellular carcinoma in Taiwanese population
-
Leu JD, Lin IF, Sun YF, et al. Association between MDM2-SNP309 and hepatocellular carcinoma in Taiwanese population. World J Gastroenterol 2009; 15: 5592-7.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 5592-5597
-
-
Leu, J.D.1
Lin, I.F.2
Sun, Y.F.3
-
28
-
-
47049091199
-
MDM2 and p53 polymorphisms are associated with the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection
-
Yoon YJ, Chang HY, Ahn SH, et al. MDM2 and p53 polymorphisms are associated with the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection. Carcinogenesis 2008; 29: 1192-6.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1192-1196
-
-
Yoon, Y.J.1
Chang, H.Y.2
Ahn, S.H.3
-
29
-
-
12244264435
-
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits
-
Purcell S, Cherny SS, Sham PC. Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003; 19: 149-50.
-
(2003)
Bioinformatics
, vol.19
, pp. 149-150
-
-
Purcell, S.1
Cherny, S.S.2
Sham, P.C.3
-
31
-
-
84959801619
-
Statistical aspects of the analysis of data from retrospective studies of disease
-
Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-48.
-
(1959)
J Natl Cancer Inst
, vol.22
, pp. 719-748
-
-
Mantel, N.1
Haenszel, W.2
-
33
-
-
9644288107
-
Assessing publication bias in genetic association studies: evidence from a recent meta-analysis
-
Munafo MR, Clark TG, Flint J. Assessing publication bias in genetic association studies: evidence from a recent meta-analysis. Psychiatry Res 2004; 129: 39-44.
-
(2004)
Psychiatry Res
, vol.129
, pp. 39-44
-
-
Munafo, M.R.1
Clark, T.G.2
Flint, J.3
-
34
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ (Clinical research ed) 1997; 315: 629-34.
-
(1997)
BMJ (Clinical research ed)
, vol.315
, pp. 629-634
-
-
Egger, M.1
Davey Smith, G.2
Schneider, M.3
Minder, C.4
-
35
-
-
0034767957
-
Cancer burden in the year 2000. The global picture
-
Parkin DM, Bray FI, Devesa SS. Cancer burden in the year 2000. The global picture. Eur J Cancer 2001; 37(Suppl. 8): S4-66.
-
(2001)
Eur J Cancer
, vol.37
, Issue.SUPPL. 8
-
-
Parkin, D.M.1
Bray, F.I.2
Devesa, S.S.3
-
36
-
-
77951974619
-
Interpretation of association signals and identification of causal variants from genome-wide association studies
-
Wang K, Dickson SP, Stolle CA, et al. Interpretation of association signals and identification of causal variants from genome-wide association studies. Am J Hum Genet 2010; 86: 730-42.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 730-742
-
-
Wang, K.1
Dickson, S.P.2
Stolle, C.A.3
-
37
-
-
63749106664
-
Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia
-
Shi H, Tan SJ, Zhong H, et al. Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia. Am J Hum Genet 2009; 84: 534-41.
-
(2009)
Am J Hum Genet
, vol.84
, pp. 534-541
-
-
Shi, H.1
Tan, S.J.2
Zhong, H.3
-
38
-
-
0035528928
-
Case-control studies of association in structured or admixed populations
-
Pritchard JK, Donnelly P. Case-control studies of association in structured or admixed populations. Theor Popul Biol 2001; 60: 227-37.
-
(2001)
Theor Popul Biol
, vol.60
, pp. 227-237
-
-
Pritchard, J.K.1
Donnelly, P.2
-
39
-
-
0034330383
-
Natives or immigrants: modern human origin in east Asia
-
Jin L, Su B. Natives or immigrants: modern human origin in east Asia. Nat Rev Genet 2000; 1: 126-33.
-
(2000)
Nat Rev Genet
, vol.1
, pp. 126-133
-
-
Jin, L.1
Su, B.2
-
40
-
-
71449083275
-
Genomic dissection of population substructure of Han Chinese and its implication in association studies
-
Xu S, Yin X, Li S, et al. Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet 2009; 85: 762-74.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 762-774
-
-
Xu, S.1
Yin, X.2
Li, S.3
|