ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5

Molecular Biology of the Cell

Volumn 23, Issue 13, 2012, Pages 2481-2489

  Hasegawa, Junya ^a   Tsujita, Kazuya ^a   Takenawa, Tadaomi ^a   Itoh, Toshiki ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 1; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 5; F ACTIN; LIPOSOME; MEMBRANE LIPID; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL STRUCTURE; CIRCULAR DORSAL RUFFLE; CYTOSKELETON; ENDOCYTOSIS; ENZYME ACTIVITY; IMMUNOFLUORESCENCE MICROSCOPY; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; RNA INTERFERENCE;

ADP-RIBOSYLATION FACTOR 1; ADP-RIBOSYLATION FACTORS; ANIMALS; CARRIER PROTEINS; CELL MEMBRANE STRUCTURES; GENE KNOCKDOWN TECHNIQUES; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HUMANS; MICE; NIH 3T3 CELLS; PINOCYTOSIS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-SIS; RNA INTERFERENCE; TIME-LAPSE IMAGING;

EID: 84863514031     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-01-0017     Document Type: Article

References (34)

1. Beemiller P, Hoppe AD, Swanson JA (2006). A phosphatidylinositol-3- kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis. PLoS Biol 4, e162.
2. Behnia R, Munro S (2005). Organelle identity and the signposts for membrane traffic. Nature 438, 597-604. (Pubitemid 41740563)
3. Braun V, Deschamps C, Raposo G, Benaroch P, Benmerah A, Chavrier P, Niedergang F (2007). AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis. Mol Biol Cell 18, 4921-4931. (Pubitemid 350246693)
4. Buccione R, Orth JD, McNiven MA (2004). Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nat Rev Mol Cell Biol 5, 647-657. (Pubitemid 39025065)
5. Campa F, Yoon HY, Ha VL, Szentpetery Z, Balla T, Randazzo PA (2009). A PH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes. J Biol Chem 284, 28069-28083.
6. Casanova JE (2007). Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors. Traffic 8, 1476-1485.
7. D'Souza-Schorey C, Chavrier P (2006). ARF proteins: roles in membrane traffic and beyond. Nat Rev Mol Cell Biol 7, 347-358.
8. Daniele T, Di Tullio G, Santoro M, Turacchio G, De Matteis MA (2008). ARAP1 regulates EGF receptor trafficking and signalling. Traffic 9, 2221-2235.
9. Donaldson JG (2003). Multiple roles for Arf6: sorting, structuring, and signaling at the plasma membrane. J Biol Chem 278, 41573-41576.
10. Donaldson JG (2008). Arfs and membrane lipids: sensing, generating and responding to membrane curvature. Biochem J 414, e1-e2.
11. Donaldson JG, Jackson CL (2011). ARF family G proteins and their regulators: roles in membrane transport, development and disease. Nat Rev Mol Cell Biol 12, 362-375.
12. Gillingham AK, Munro S (2007). The small G proteins of the Arf family and their regulators. Annu Rev Cell Dev Biol 23, 579-611.
13. Gu Z, Noss EH, Hsu VW, Brenner MB (2011). Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration. J Cell Biol 193, 61-70.
14. Ha VL, Bharti S, Inoue H, Vass WC, Campa F, Nie Z, de Gramont A, Ward Y, Randazzo PA (2008). ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion. J Biol Chem 283, 14915-14926.
15. Hasegawa J, Tokuda E, Tenno T, Tsujita K, Sawai H, Hiroaki H, Takenawa T, Itoh T (2011). SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain. J Cell Biol 193, 901-916.
16. Inoue H, Randazzo PA (2007). Arf GAPs and their interacting proteins. Traffic 8, 1465-1475. (Pubitemid 47591332)
17. Jackson TR, Brown FD, Nie Z, Miura K, Foroni L, Sun J, Hsu VW, Donaldson JG, Randazzo PA (2000). ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. J Cell Biol 151, 627-638.
18. Kang SA, Lee ES, Yoon HY, Randazzo PA, Lee ST (2010). PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1. J Biol Chem 285, 26013-26021.
19. Krugmann S et al. (2002). Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. Mol Cell 9, 95-108. (Pubitemid 34127774)
20. Krugmann S, Andrews S, Stephens L, Hawkins PT (2006). ARAP3 is essential for formation of lamellipodia after growth factor stimulation. J Cell Sci 119, 425-432.
21. Kumari S, Mayor S (2008). ARF1 is directly involved in dynamin-independent endocytosis. Nat Cell Biol 10, 30-41.
22. Mercer J, Helenius A (2009). Virus entry by macropinocytosis. Nat Cell Biol 11, 510-520.
23. Miura K, Jacques KM, Stauffer S, Kubosaki A, Zhu K, Hirsch DS, Resau J, Zheng Y, Randazzo PA (2002). ARAP1: a point of convergence for Arf and Rho signaling. Mol Cell 9, 109-119. (Pubitemid 34127775)
24. Oikawa T, Itoh T, Takenawa T (2008). Sequential signals toward podosome formation in NIH-src cells. J Cell Biol 182, 157-169. (Pubitemid 352008629)
25. Orth JD, Krueger EW, Weller SG, McNiven MA (2006). A novel endocytic mechanism of epidermal growth factor receptor sequestration and internalization. Cancer Res 66, 3603-3610.
26. Randazzo PA, Andrade J, Miura K, Brown MT, Long YQ, Stauffer S, Roller P, Cooper JA (2000). The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton. Proc Natl Acad Sci USA 97, 4011-4016. (Pubitemid 30226078)
27. Riedl J et al. (2008). Lifeact: a versatile marker to visualize F-actin. Nat Methods 5, 605-607. (Pubitemid 351911864)
28. Sabe H, Onodera Y, Mazaki Y, Hashimoto S (2006). ArfGAP family proteins in cell adhesion, migration and tumor invasion. Curr Opin Cell Biol 18, 558-564. (Pubitemid 44332908)
29. Spang A, Shiba Y, Randazzo PA (2010). Arf GAPs: gatekeepers of vesicle generation. FEBS Lett 584, 2646-2651.
30. Volpicelli-Daley LA, Li Y, Zhang CJ, Kahn RA (2005). Isoform-selective effects of the depletion of ADP-ribosylation factors 1-5 on membrane traffic. Mol Biol Cell 16, 4495-4508. (Pubitemid 41416436)
31. Wang D, Tan YC, Kreitzer GE, Nakai Y, Shan D, Zheng Y, Huang XY (2006). G proteins G12 and G13 control the dynamic turnover of growth factor-induced dorsal ruffles. J Biol Chem 281, 32660-32667. (Pubitemid 46036821)
32. Yoon HY, Lee JS, Randazzo PA (2008). ARAP1 regulates endocytosis of EGFR. Traffic 9, 2236-2252.
33. Yoon HY, Miura K, Cuthbert EJ, Davis KK, Ahvazi B, Casanova JE, Randazzo PA (2006). ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP. J Cell Sci 119, 4650-4666. (Pubitemid 44964262)
34. Zeng Y, Lai T, Koh CG, LeDuc PR, Chiam KH (2011). Investigating circular dorsal ruffles through varying substrate stiffness and mathematical modeling. Biophys J 101, 2122-2130.