A dynamic multi-compartmental model of DNA methylation with demonstrable predictive value in hematological malignancies

Journal of Theoretical Biology

Volumn 310, Issue , 2012, Pages 14-20

  McGovern, Andrew P ^a   Powell, Benjamin E ^b   Chevassut, Timothy J T ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

CpG island; DNA methyltransferase (Dnmt); Hydroxymethylcytosine; Methylcytosine; Tet protein

Indexed keywords

CARRIER PROTEIN; CYTOSINE; DNA METHYLTRANSFERASE; HYDROXYMETHYLCYTOSINE; METHYLCYTOSINE; PROTEIN TET; UNCLASSIFIED DRUG;

DNA; HEMATOLOGY; METHYLATION; MODELING; PROTEIN;

ARTICLE; CARCINOGENESIS; COMPARTMENT MODEL; CPG ISLAND; DEMETHYLATION; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; GENE DISRUPTION; GENETIC MODEL; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; MATHEMATICAL COMPUTING; MODULATION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN FUNCTION;

DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENESIS, GENETIC; GENOME, HUMAN; HEMATOLOGIC NEOPLASMS; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MODELS, GENETIC;

EID: 84863497603     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2012.06.018     Document Type: Article

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