Interspecies signaling through QscR, a quorum receptor of Pseudomonas aeruginosa

Molecules and Cells

Volumn 33, Issue 1, 2012, Pages 53-59

  Ha, Changwan ^a   Park, Seong Joon ^a   Im, Su Jin ^a   Park, Su Jin ^a   Lee, Joon Hee ^a  

^a Pusan National University   (South Korea)

Author keywords

Interspecies signaling; LasR; Pseudomonas aeruginosa; QscR; Quorum

Indexed keywords

BACTERIAL PROTEIN; N ACYLHOMOSERINE LACTONE; PROTEIN QSCR; RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BINDING SITE; BURKHOLDERIA; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC VARIABILITY; GENOTYPE; NONHUMAN; PLASMID; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS FLUORESCENS; REGULON; SIGNAL TRANSDUCTION;

BACTERIAL PROTEINS; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

PSEUDOMONAS AERUGINOSA; PSEUDOMONAS FLUORESCENS;

EID: 84863495395     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-012-2208-2     Document Type: Article

References (29)

1. Choi, Y., Park, H. Y., Park, S. J., Kim, S. K., Ha, C., Im, S. J., and Lee, J. H. (2011). Growth phase-differential quorum sensing regulation of anthranilate metabolism in Pseudomonas aeruginosa. Mol. Cells 32, 57-65.
2. Chugani, S. A., Whiteley, M., Lee, K. M., D'Argenio, D., Manoil, C., and Greenberg, E. P. (2001). QscR, a modulator of quorumsensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA 98, 2752-2757. (Pubitemid 32209555)
3. Conway, B. A., and Greenberg, E. P. (2002). Quorum-sensing signals and quorum-sensing genes in Burkholderia vietnamiensis. J. Bacteriol. 184, 1187-1191. (Pubitemid 34113388)
4. Daniels, R., Vanderleyden, J., and Michiels, J. (2004). Quorum sensing and swarming migration in bacteria. FEMS Microbiol. Rev. 28, 261-289. (Pubitemid 38721406)
5. Farinha, M. A., and Kropinski, A. M. (1990). Construction of broadhost-range plasmid vectors for easy visible selection and analysis of promoters. J. Bacteriol. 172, 3496-3499. (Pubitemid 20179813)
6. Fuqua, C. (2006). The QscR quorum-sensing regulon of Pseudomonas aeruginosa: an orphan claims its identity. J. Bacteriol. 188, 3169-3171.
7. Fuqua, C., and Greenberg, E. P. (2002). Listening in on bacteria: acyl-homoserine lactone signalling. Nat. Rev. Mol. Cell. Biol. 3, 685-695. (Pubitemid 34987789)
8. Hentzer, M., Wu, H., Andersen, J. B., Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., et al. (2003). Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 22, 3803-3815. (Pubitemid 36975709)
9. Khan, S. R., Mavrodi, D. V., Jog, G. J., Suga, H., Thomashow, L. S., and Farrand, S. K. (2005). Activation of the phz operon of Pseudomonas fluorescens 2-79 requires the LuxR homolog PhzR, N-(3-OH-Hexanoyl)-L-homoserine lactone produced by the LuxI homolog PhzI, and a cis-acting phz box. J. Bacteriol. 187, 6517-6527. (Pubitemid 41318411)
10. Ledgham, F., Ventre, I., Soscia, C., Foglino, M., Sturgis, J. N., and Lazdunski, A. (2003). Interactions of the quorum sensing regulator QscR: interaction with itself and the other regulators of Pseudomonas aeruginosa LasR and RhlR. Mol. Microbiol. 48, 199-210. (Pubitemid 36411477)
11. Lee, J. H., Lequette, Y., and Greenberg, E. P. (2006). Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor. Mol. Microbiol. 59, 602-609.
12. Lequette, Y., Lee, J. H., Ledgham, F., Lazdunski, A., and Greenberg, E. P. (2006). A distinct QscR regulon in the Pseudomonas aeruginosa quorum-sensing circuit. J. Bacteriol. 188, 3365-3370.
13. Mattiuzzo, M., Bertani, I., Ferluga, S., Cabrio, L., Bigirimana, J., Guarnaccia, C., Pongor, S., Maraite, H., and Venturi, V. (2011). The plant pathogen Pseudomonas fuscovaginae contains two conserved quorum sensing systems involved in virulence and negatively regulated by RsaL and the novel regulator RsaM. Environ. Microbiol. 13, 145-162.
14. Newman, J. R., and Fuqua, C. (1999). Broad-host-range expression vectors that carry the L-arabinose-inducible Escherichia coli araBAD promoter and the araC regulator. Gene 227, 197-203. (Pubitemid 29104855)
15. Oinuma, K., and Greenberg, E. P. (2011). Acyl-homoserine lactone binding to and stability of the orphan Pseudomonas aeruginosa quorum-sensing signal receptor QscR. J. Bacteriol. 193, 421-428.
16. Pearson, J. P., Passador, L., Iglewski, B. H., and Greenberg, E. P. (1995). A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA 92, 1490-1494.
17. Pearson, J. P., Pesci, E. C., and Iglewski, B. H. (1997). Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes. J. Bacteriol. 179, 5756-5767. (Pubitemid 27398275)
18. Sambrook, J. E., Fritsch, F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual (Cold Spring Harbor, N. Y., USA: Cold Spring Harbor Laboratory Press)
19. Schuster, M., and Greenberg, E. P. (2006). A network of networks: quorum-sensing gene regulation in Pseudomonas aeruginosa. Int. J. Med. Microbiol. 296, 73-81. (Pubitemid 43375989)
20. Schuster, M., and Greenberg, E. P. (2007). Early activation of quorum sensing in Pseudomonas aeruginosa reveals the architecture of a complex regulon. BMC Genomics 8, 287.
21. Schuster, M., Lostroh, C. P., Ogi, T., and Greenberg, E. P. (2003). Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J. Bacteriol. 185, 2066-2079. (Pubitemid 36363167)
22. Schuster, M., Urbanowski, M. L., and Greenberg, E. P. (2004). Promoter specificity in Pseudomonas aeruginosa quorum sensing revealed by DNA binding of purified LasR. Proc. Natl. Acad. Sci. USA 101, 15833-15839. (Pubitemid 39507888)
23. Smith, R. S., and Iglewski, B. H. (2003). P. aeruginosa quorumsensing systems and virulence. Curr. Opin. Microbiol. 6, 56-60.
24. Venturi, V. (2006). Regulation of quorum sensing in Pseudomonas. FEMS Microbiol. Rev. 30, 274-291.
25. Venturi, V., Friscina, A., Bertani, I., Devescovi, G., and Aguilar, C. (2004). Quorum sensing in the Burkholderia cepacia complex. Res. Microbiol. 155, 238-244. (Pubitemid 38624170)
26. Wagner, V. E., Bushnell, D., Passador, L., Brooks, A. I., and Iglewski, B. H. (2003). Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment. J. Bacteriol. 185, 2080-2095. (Pubitemid 36363168)
27. Wagner-Dobler, I., Thiel, V., Eberl, L., Allgaier, M., Bodor, A., Meyer, S., Ebner, S., Hennig, A., Pukall, R., and Schulz, S. (2005). Discovery of complex mixtures of novel long-chain quorum sensing signals in free-living and host-associated marine alphaproteobacteria. Chembiochem 6, 2195-2206.
28. Whiteley, M., and Greenberg, E. P. (2001). Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes. J. Bacteriol. 183, 5529-5534. (Pubitemid 32880581)
29. Whiteley, M., Lee, K. M., and Greenberg, E. P. (1999). Identification of genes controlled by quorum sensing in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA 96, 13904-13909.