Intra- and inter-cortical motor excitability in Alzheimer's disease

Journal of Neural Transmission

Volumn 119, Issue 5, 2012, Pages 605-612

  Hoeppner, Jacqueline ^a   Wegrzyn, Martin ^b   Thome, Johannes ^a   Bauer, Alexandra ^a   Oltmann, Imke ^a   Buchmann, Johannes ^a   Teipel, Stefan ^b  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

Alzheimer's disease; Motor cortical excitability; Transcranial magnetic stimulation

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; EVOKED MUSCLE RESPONSE; FEMALE; HEMISPHERE; HUMAN; MALE; MINI MENTAL STATE EXAMINATION; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NEUROPSYCHOLOGY; PRIORITY JOURNAL; TRANSCRANIAL MAGNETIC STIMULATION;

AGED; ALZHEIMER DISEASE; EVOKED POTENTIALS, MOTOR; FEMALE; HUMANS; MALE; MOTOR CORTEX; NEURAL INHIBITION;

EID: 84863483180     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-011-0738-y     Document Type: Article

References (52)

1. Abbruzzese G, Trompetto C (2002) Clinical and research methods for evaluating cortical excitability. J Clin Neurophysiol 19(4):307-321
2. Agosta F, Rocca MA, Pagani E, Absinta M, Magnani G, Marcone A, Falautano M, Comi G, Gorno-Tempini ML, Filippi M (2010) Sensorimotor network rewiring in mild cognitive impairment and Alzheimer's disease. Hum Brain Mapp 31(4):515-525
3. Alagona G, Bella R, Ferri R, Carnemolla A, Pappalardo A, Costanzo E, Pennisi G (2001) Transcranial magnetic stimulation in Alzheimer disease: motor cortex excitability and cognitive severity. Neurosci Lett 314(1-2):57-60
4. Alagona G, Ferri R, Pennisi G, Carnemolla A, Maci T, Domina E, Maertens de Noordhout A, Bella R (2004) Motor cortex excitability in Alzheimer's disease and in subcortical ischemic vascular dementia. Neurosci Lett 362(2):95-98
5. Buchmann J, Gierow W, Weber S, Hoeppner J, Klauer T, Wittstock M, Benecke R, Haessler F, Wolters A (2006) Modulation of transcallosally mediated motor inhibition in children with attention deficit hyperactivity disorder (ADHD) by medication with methylphenidate (MPH). Neurosci Lett 405(1-2):14-18
6. Chen R (2004) Interactions between inhibitory and excitatory circuits in the human motor cortex. Exp Brain Res (Experimentelle Hirnforschung) 154(1):1-10
7. Chen JY, Stern Y, Sano M, Mayeux R (1991) Cumulative risks of developing extrapyramidal signs, psychosis, or myoclonus in the course of Alzheimer's disease. Arch Neurol 48(11):1141-1143
8. de Lacoste MC, Kirkpatrick JB, Ross ED (1985) Topography of the human corpus callosum. J Neuropathol Exp Neurol 44(6):578-591
9. Di Lazzaro V, Oliviero A, Pilato F, Saturno E, Dileone M, Marra C, Daniele A, Ghirlanda S, Gainotti G, Tonali PA (2004) Motor cortex hyperexcitability to transcranial magnetic stimulation in Alzheimer's disease. J Neurol Neurosurg Psychiatry 75(4):555-559
10. Di Paola M, Di Iulio F, Cherubini A, Blundo C, Casini AR, Sancesario G, Passafiume D, Caltagirone C, Spalletta G (2010a) When, where, and how the corpus callosum changes in MCI and AD: a multimodal MRI study. Neurology 74(14):1136-1142
11. Di Paola M, Luders E, Di Iulio F, Cherubini A, Passafiume D, Thompson PM, Caltagirone C, Toga AW, Spalletta G (2010b) Callosal atrophy in mild cognitive impairment and Alzheimer's disease: different effects in different stages. Neuroimage 49(1):141-149
12. Di Paola M, Spalletta G, Caltagirone C (2010c) In vivo structural neuroanatomy of corpus callosum in Alzheimer's disease and mild cognitive impairment using different MRI techniques: a review. J Alzheimers Dis 20(1):67-95
13. Ferbert A, Priori A, Rothwell JC, Day BL, Colebatch JG, Marsden CD (1992) Interhemispheric inhibition of the human motor cortex. J Physiol 453:525-546
14. Ferreri F, Pauri F, Pasqualetti P, Fini R, Dal Forno G, Rossini PM (2003) Motor cortex excitability in Alzheimer's disease: a transcranial magnetic stimulation study. Ann Neurol 53(1): 102-108
15. Ferri CP, Prince M, Brayne C, Brodaty H, Fratiglioni L, Ganguli M, Hall K, Hasegawa K, Hendrie H, Huang Y, Jorm A, Mathers C, Menezes PR, Rimmer E, Scazufca M (2005) Global prevalence of dementia: a Delphi consensus study. Lancet 366(9503): 2112-2117
16. First MB, Spitzer RL, Gibbon M, Williams JBW (1996) Structured clinical interview for DSM-IV axis I disorders, clinician version (SCID-CV). American Psychiatric Press, Washington DC
17. Folstein MF, Folstein SE, McHugh PR (1975) "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Research 12(3):189-198
18. Funkenstein HH, Albert MS, Cook NR, West CG, Scherr PA, Chown MJ, Pilgrim D, Evans DA (1993) Extrapyramidal signs and other neurologic findings in clinically diagnosed Alzheimer's disease. A community-based study. Arch Neurol 50(1):51-56
19. Hallett M (2000) Transcranial magnetic stimulation and the human brain. Nature 406(6792):147-150
20. Hoeppner J, Kunesch E, Großmann A, Tolzin C-J, Schulz M, Schläfke D, Ernst K (2000) Dysfunction of transcallosally mediated inhibition and callosal morphology in patients with schizophrenia. Acta Psychiatr Scand 104:227-235
21. Hoeppner J, Wandschneider R, Neumeyer M, Gierow W, Haessler F, Herpertz SC, Buchmann J (2008) Impaired transcallosally mediated motor inhibition in adults with attention-deficit/hyperactivity disorder is modulated by methylphenidate. J Neural Transm 115(5):777-785
22. Hoppner J, Kunesch E, Buchmann J, Hess A, Grossmann A, Benecke R (1999) Demyelination and axonal degeneration in corpus callosum assessed by analysis of transcallosally mediated inhibition in multiple sclerosis. Clin Neurophysiol 110(4):748-756
23. Kabay SC, Gulbandilar E, Ozden H, Ozbag D, Guven G, Adapinar B, Durmaz R (2009) Evaluation of the size and area of the corpus callosum with the Osiris method in Alzheimer's disease. Neurodegenerative diseases 6(4):148-153
24. Khedr EM, Ahmed MA, Darwish ES, Ali AM (2011) The relationship between motor cortex excitability and severity of Alzheimer's disease: a transcranial magnetic stimulation study. Neurophysiol Clin (Clinical neurophysiology) 41(3):107-113
25. Korchounov A, Ilic TV, Schwinge T, Ziemann U (2005) Modification of motor cortical excitability by an acetylcholinesterase inhibitor. Exp Brain Res (Experimentelle Hirnforschung) 164(3):399-405
26. Kujirai T, Caramia MD, Rothwell JC, Day BL, Thompson PD, Ferbert A, Wroe S, Asselman P, Marsden CD (1993) Corticocortical inhibition in human motor cortex. J Physiol 471:501-519
27. Lee DY, Fletcher E, Martinez O, Zozulya N, Kim J, Tran J, Buonocore M, Carmichael O, DeCarli C (2010) Vascular and degenerative processes differentially affect regional interhemispheric connections in normal aging, mild cognitive impairment, and Alzheimer disease. Stroke 41(8):1791-1797
28. Liepert J, Bar KJ, Meske U, Weiller C (2001) Motor cortex disinhibition in Alzheimer's disease. Clin Neurophysiol 112(8):1436-1441
29. Mangialasche F, Solomon A, Winblad B, Mecocci P, Kivipelto M (2010) Alzheimer's disease: clinical trials and drug development. Lancet Neurol 9(7):702-716
30. Martorana A, Stefani A, Palmieri MG, Esposito Z, Bernardi G, Sancesario G, Pierantozzi M (2008) L-dopa modulates motor cortex excitability in Alzheimer's disease patients. J Neural Transm 115(9):1313-1319
31. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34(7):939-944
32. Meyer BU (1992) Die Magnetstimulation des Nervensystems. Springer Verlag, Berlin
33. Meyer BU, Roericht S, GHv Einsiedel, Kruggel F, Weindl A (1995) Inhibitory and excitatory interhemispheric transfer between motor cortical areas in normal subjects and patients with abnormalities of the corpus callosum. Brain 118:429-440
34. Meyer BU, Roericht S, Woiciechowsky C (1998) Topography of fibers in the human corpus callosum mediating interhemispheric inhibition between the motor cortices. Ann Neurol 43(3):360-369
35. Moller T, Born C, Reiser MF, Moller HJ, Hampel H, Teipel SJ (2009) Alzheimer's disease and vascular dementia. Determination of atrophy of the corpus callosum and cerebral cortex. Der Nervenarzt 80 (1):54-61
36. Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, Fillenbaum G, Mellits ED, Clark C (1989) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology 39 (9):1159-1165
37. Nardone R, Bratti A, Tezzon F (2006) Motor cortex inhibitory circuits in dementia with Lewy bodies and in Alzheimer's disease. J Neural Transm 113(11):1679-1684
38. Olazaran J, Prieto J, Cruz I, Esteban A (2010) Cortical excitability in very mild Alzheimer's disease: a long-term follow-up study. J Neurol 257(12):2078-2085
39. Oldfield RC (1971) The assessment and analysis of handeness: The Edinburgh inventory. Neuropsychologia 9:110-111
40. Pepin JL, Bogacz D, de Pasqua V, Delwaide PJ (1999) Motor cortex inhibition is not impaired in patients with Alzheimer's disease: evidence from paired transcranial magnetic stimulation. J Neurol Sci 170(2):119-123
41. Pierantozzi M, Panella M, Palmieri MG, Koch G, Giordano A, Marciani MG, Bernardi G, Stanzione P, Stefani A (2004) Different TMS patterns of intracortical inhibition in early onset Alzheimer dementia and frontotemporal dementia. Clin Neurophysiol 115(10):2410-2418
42. Roericht S, Irlbacher K, Petrow E, Meyer BU (1997) Normwerte transkallosal und kortikospinal vermittelter Effekte einer hemisphä renselektiven magnetischen Kortexreizung beim Menschen. EEG-EMG 28:34-38
43. Rossini PM, Rossi S (1998) Clinical applications of motor evoked potentials. Electroencephalogr Clin Neurophysiol 106:180-194
44. Shulman KI (2000) Clock-drawing: is it the ideal cognitive screening test? Int J Geriatr Psychiatry 15(6):548-561
45. Teipel SJ, Hampel H, Pietrini P, Alexander GE, Horwitz B, Daley E, Moller HJ, Schapiro MB, Rapoport SI (1999) Region-specific corpus callosum atrophy correlates with the regional pattern of cortical glucose metabolism in Alzheimer disease. Arch Neurol 56(4):467-473
46. Teipel SJ, Bayer W, Alexander GE, Zebuhr Y, Teichberg D, Kulic L, Schapiro MB, Moller HJ, Rapoport SI, Hampel H (2002) Progression of corpus callosum atrophy in Alzheimer disease. Arch Neurol 59(2):243-248
47. Teipel SJ, Bayer W, Alexander GE, Bokde AL, Zebuhr Y, Teichberg D, Muller-Spahn F, Schapiro MB, Moller HJ, Rapoport SI, Hampel H (2003) Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer's disease in relation to dementia severity: evidence for early neocortical degeneration. Neurobiol Aging 24(1):85-94
48. Valls-Sole J, Pascual-Leone A, Wassermann EM, Hallett M (1992) Human motor evoked responses to paired transcranial magnetic stimuli. Electroencephalogr Clin Neurophysiol 85(6):355-364
49. Werhahn KJ, Kunesch E, Noachtar S, Benecke R, Classen J (1999) Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans. J Physiol 517(Pt 2):591-597
50. Wolters A, Classen J, Kunesch E, Grossmann A, Benecke R (2004) Measurements of transcallosally mediated cortical inhibition for differentiating parkinsonian syndromes.MovDisord 19(5):518-528
51. Yamauchi H, Fukuyama H, Nagahama Y, Katsumi Y, Hayashi T, Oyanagi C, Konishi J, Shio H (2000) Comparison of the pattern of atrophy of the corpus callosum in frontotemporal dementia, progressive supranuclear palsy, and Alzheimer's disease. J Neurol Neurosurg Psychiatry 69(5):623-629
52. Ziemann U, Lonnecker S, Steinhoff BJ, Paulus W (1996) Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranialmagnetic stimulation study. Ann Neurol 40(3):367-378