Cooling and seizure burden in term neonates: An observational study

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 97, Issue 4, 2012, Pages

  Low, Evonne ^a   Boylan, Geraldine B ^a   Mathieson, Sean R ^b   Murray, Deirdre M ^a   Korotchikova, Irina ^a   Stevenson, Nathan J ^a   Livingstone, Vicki ^a   Rennie, Janet M ^b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; COOLING; ELECTROENCEPHALOGRAPHY; FEMALE; HUMAN; HYPOXIC ISCHEMIC ENCEPHALOPATHY; INFANT; MALE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEIZURE; TERM BIRTH;

ANTICONVULSANTS; COMBINED MODALITY THERAPY; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INFANT CARE; INFANT, NEWBORN; MALE; MONITORING, PHYSIOLOGIC; RETROSPECTIVE STUDIES; SEIZURES, FEBRILE; TREATMENT OUTCOME;

EID: 84863481363     PISSN: 13592998     EISSN: 14682052     Source Type: Journal    
DOI: 10.1136/archdischild-2011-300716     Document Type: Article

References (36)

1. Volpe JJ. Neurology of the Newborn. Fifth edition. Philadelphia, PA: WB Saunders Company 2008:203-44.
2. Glass HC, Glidden D, Jeremy RJ, et al. Clinical Neonatal Seizures are independently associated with outcome in infants at risk for hypoxic-ischemic brain injury. J Pediatr 2009;155:318-23.
3. van Rooij LG, de Vries LS, Handryastuti S, et al. Neurodevelopmental outcome in term infants with status epilepticus detected with amplitude-integrated electroencephalography. Pediatrics 2007;120:e354-63. (Pubitemid 47219486)
4. Murray DM, Boylan GB, Ali I, et al. Defining the gap between electrographic seizure burden, clinical expression and staff recognition of neonatal seizures. Arch Dis Child Fetal Neonatal Ed 2008;93:F187-91. (Pubitemid 352039284)
5. Shellhaas RA, Soaita AI, Clancy RR. Sensitivity of amplitude-integrated electroencephalography for neonatal seizure detection. Pediatrics 2007;120:770-7. (Pubitemid 47549565)
6. Rennie JM, Chorley G, Boylan GB, et al. Non-expert use of the cerebral function monitor for neonatal seizure detection. Arch Dis Child Fetal Neonatal Ed 2004;89:F37-40. (Pubitemid 38125476)
7. Edwards AD, Brocklehurst P, Gunn AJ, et al. Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data. BMJ 2010;340:c363.
8. National Institute for Health and Clinical Excellence (NICE). Controlled cooling to treat newborn babies with brain injury caused by oxygen shortage during birth. Information about NICE interventional procedure guidance 347; Reference No N2184. www.nice.org.uk (accessed 10 May 2010).
9. Thoresen M, Penrice J, Lorek A, et al. Mild hypothermia after severe transient hypoxia-ischemia ameliorates delayed cerebral energy failure in the newborn piglet. Pediatr Res 1995;37:667-70.
10. Gunn AJ, Gunn TR, de Haan HH, et al. Dramatic neuronal rescue with prolonged selective head cooling after ischemia in fetal lambs. J Clin Invest 1997;99:248-56. (Pubitemid 27053465)
11. Evans DJ, Levene M. Hypoxic-ischemic injury. In: Rennie JM, Robertson NRC, eds. Textbook of Neonatology. Edinburgh: Churchill Livingstone 1999:1231-51.
12. Vento M, de Vries LS, Alberola A, et al. Approach to seizures in the neonatal period: a European perspective. Acta Paediatr 2010;99:497-501.
13. Bartha AI, Shen J, Katz KH, et al. Neonatal seizures: multicenter variability in current treatment practices. Pediatr Neurol 2007;37:85-90. (Pubitemid 47187647)
14. Klem GH, Lüders HO, Jasper HH, et al. The ten-twenty electrode system of the International Federation. The International Federation of Clinical Neurophysiology. Electroencephalogr Clin Neurophysiol Suppl 1999;52:3-6.
15. Clancy RR, Legido A. The exact ictal and interictal duration of electroencephalographic neonatal seizures. Epilepsia 1987;28:537-41. (Pubitemid 17146603)
16. Scher MS, Hamid MY, Steppe DA, et al. Ictal and interictal electrographic seizure durations in preterm and term neonates. Epilepsia 1993;34:284-8. (Pubitemid 23106755)
17. Ortibus EL, Sum JM, Hahn JS. Predictive value of EEG for outcome and epilepsy following neonatal seizures. Electroencephalogr Clin Neurophysiol 1996;98:175-85. (Pubitemid 26110261)
18. Kwon JM, Guillet R, Shankaran S, et al. Clinical seizures in neonatal hypoxicischemic encephalopathy have no independent impact on neurodevelopmental outcome: secondary analyses of data from the neonatal research network hypothermia trial. J Child Neurol 2011;26:322-8.
19. Simbruner G, Mittal RA, Rohlmann F, et al. Systemic hypothermia after neonatal encephalopathy: outcomes of neo.nEURO.network RCT. Pediatrics 2010;126:e771-8.
20. Yap V, Engel M, Takenouchi T, et al. Seizures are common in term infants undergoing head cooling. Pediatr Neurol 2009;41:327-31.
21. Azzopardi D, Strohm B, Edwards AD, et al. Treatment of asphyxiated newborns with moderate hypothermia in routine clinical practice: how cooling is managed in the UK outside a clinical trial. Arch Dis Child Fetal Neonatal Ed 2009;94:F260-4.
22. Bennet L, Dean JM, Wassink G, et al. Differential effects of hypothermia on early and late epileptiform events after severe hypoxia in preterm fetal sheep. J Neurophysiol 2007;97:572-8. (Pubitemid 46143380)
23. Tooley JR, Satas S, Porter H, et al. Head cooling with mild systemic hypothermia in anesthetized piglets is neuroprotective. Ann Neurol 2003;53:65-72. (Pubitemid 36083830)
24. Busto R, Globus MY, Dietrich WD, et al. Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke 1989;20:904-10.
25. Nakashima K, Todd MM. Effects of hypothermia on the rate of excitatory amino acid release after ischemic depolarization. Stroke 1996;27:913-18. (Pubitemid 26142523)
26. Globus MY, Alonso O, Dietrich WD, et al. Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia. J Neurochem 1995;65:1704-11.
27. Barks JD, Liu YQ, Shangguan Y, et al. Phenobarbital augments hypothermic neuroprotection. Pediatr Res 2010;67:532-7.
28. Painter MJ, Scher MS, Stein AD, et al. Phenobarbital compared with phenytoin for the treatment of neonatal seizures. N Engl J Med 1999;341:485-9. (Pubitemid 29372888)
29. Sarkar S, Barks JD, Bapuraj JR, et al. Does phenobarbital improve the effectiveness of therapeutic hypothermia in infants with hypoxic-ischemic encephalopathy? J Perinatol Published Online First: 28 April 2011. doi:10.1038/jp.2011.41.
30. Dzhala VI, Talos DM, Sdrulla DA, et al. NKCC1 transporter facilitates seizures in the developing brain. Nat Med 2005;11:1205-13. (Pubitemid 43093668)
31. Róka A, Melinda KT, Vásárhelyi B, et al. Elevated morphine concentrations in neonates treated with morphine and prolonged hypothermia for hypoxic ischemic encephalopathy. Pediatrics 2008;121:e844-9.
32. Filippi L, la Marca G, Cavallaro G, et al. Phenobarbital for neonatal seizures in hypoxic ischemic encephalopathy: a pharmacokinetic study during whole body hypothermia. Epilepsia 2011;52:794-801.
33. Murray DM, Ryan CA, Boylan GB, et al. Prediction of seizures in asphyxiated neonates: correlation with continuous video-electroencephalographic monitoring. Pediatrics 2006;118:41-6. (Pubitemid 46071145)
34. Wusthoff CJ, Dlugos DJ, Gutierrez-Colina A, et al. Electrographic seizures during therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy. J Child Neurol 2011;26:724-8.
35. Nash KB, Bonifacio SL, Glass HC, et al. Video-EEG monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. Neurology 2011;76:556-62.
36. Hamelin S, Delnard N, Cneude F, et al. Influence of hypothermia on the prognostic value of early EEG in full-term neonates with hypoxic ischemic encephalopathy. Neurophysiol Clin 2011;41:19-27.