HIF1A C1772T polymorphism leads to HIF-1αmRNA overexpression in prostate cancer patients

Cancer Biology and Therapy

Volumn 13, Issue 9, 2012, Pages 720-726

  Vainrib, Michael ^a   Golan, Maya ^b   Amir, Sharon ^b   Dang, Duyen T ^c   Dang, Long H ^d   Bar Shira, Anat ^b   Orr Urtreger, Avi ^b   Matzkin, Haim ^b   Mabjeesh, Nicola J ^b  

^a MEIR MEDICAL CENTER   (Israel)

^b TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

C1772T; Cancer; Hypoxia inducible factor 1 ; mRNA; Polymorphism; Prostate

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA;

AGED; ARTICLE; CANCER CELL; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; GAIN OF FUNCTION MUTATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN CELL; LEUKOCYTE; MALE; NUCLEOTIDE SEQUENCE; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN STABILITY; TRANSCRIPTION INITIATION; WILD TYPE;

AGED; AGED, 80 AND OVER; CELL HYPOXIA; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HALF-LIFE; HCT116 CELLS; HOMOZYGOTE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LEUKOCYTES, MONONUCLEAR; LUCIFERASES, FIREFLY; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS; RESPONSE ELEMENTS; RNA STABILITY;

EID: 84863475962     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.20554     Document Type: Article

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