Automated quantitative Rb-82 3D PET/CT myocardial perfusion imaging: Normal limits and correlation with invasive coronary angiography

Journal of Nuclear Cardiology

Volumn 19, Issue 2, 2012, Pages 265-276

  Nakazato, Ryo ^a   Berman, Daniel S ^a,b   Dey, Damini ^a,b   Le Meunier, Ludovic ^c   Hayes, Sean W ^a,b   Fermin, Jimmy S ^a   Cheng, Victor Y ^a   Thomson, Louise E J ^a,b   Friedman, John D ^a,b   Germano, Guido ^a,b   Slomka, Piotr J ^a,b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Siemens Medical Solutions   (United States)

Author keywords

3D; Coronary artery Disease; Myocardial perfusion imaging; PET CT; Quantification

Indexed keywords

ADENOSINE; RUBIDIUM 82;

AGED; ANGIOCARDIOGRAPHY; ARTICLE; AUTOANALYSIS; CARDIOVASCULAR PARAMETERS; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER PROGRAM; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; DIAGNOSTIC ACCURACY; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAN TRANSIENT ISCHEMIC DILATION RATIO; MYOCARDIAL PERFUSION IMAGING; PHARMACOLOGIC STRESS TESTING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; TOTAL PERFUSION DEFICIT;

AGED; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MALE; MYOCARDIAL PERFUSION IMAGING; PATTERN RECOGNITION, AUTOMATED; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; RUBIDIUM RADIOISOTOPES; SENSITIVITY AND SPECIFICITY; STATISTICS AS TOPIC; SUBTRACTION TECHNIQUE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84863467794     PISSN: 10713581     EISSN: 15326551     Source Type: Journal    
DOI: 10.1007/s12350-011-9496-3     Document Type: Article

References (38)

1. Di Carli MF, Hachamovitch R. New technology for noninvasive evaluation of coronary artery disease. Circulation 2007;115:1464-80. (Pubitemid 46648384)
2. Sampson UK, Dorbala S, Limaye A, Kwong R, Di Carli MF. Diagnostic accuracy of rubidium-82 myocardial perfusion imaging with hybrid positron emission tomography/computed tomography in the detection of coronary artery disease. J Am Coll Cardiol 2007;49:1052-8. (Pubitemid 46349498)
3. Dorbala S, Vangala D, Sampson U, Limaye A, Kwong R, Di Carli MF. Value of vasodilator left ventricular ejection fraction reserve in evaluating the magnitude of myocardium at risk and the extent of angiographic coronary artery disease: A 82Rb PET/CT study. J Nucl Med 2007;48:349-58. (Pubitemid 47604916)
4. Stewart RE, Schwaiger M, Molina E, Popma J, Gacioch GM, Kalus M, et al. Comparison of rubidium-82 positron emission tomography and thallium-201 SPECT imaging for detection of coronary artery disease. Am J Cardiol 1991;67:1303-10.
5. Go RT, Marwick TH, MacIntyre WJ, Saha GB, Neumann DR, Underwood DA, et al. A prospective comparison of rubidium-82 PET and thallium-201 SPECT myocardial perfusion imaging utilizing a single dipyridamole stress in the diagnosis of coronary artery disease. J Nucl Med 1990;31:1899-905.
6. Bateman TM, Heller GV, McGhie AI, Friedman JD, Case JA, Bryngelson JR, et al. Diagnostic accuracy of rest/stress ECG-gated Rb-82 myocardial perfusion PET: Comparison with ECG-gated Tc-99 m sestamibi SPECT. J Nucl Cardiol 2006;13:24-33. (Pubitemid 43192726)
7. Nishina H, Slomka P, Abidov A, Yoda S, Akincioglu C, Kang X, et al. Combined supine and prone quantitative myocardial perfusion SPECT: Method development and clinical validation in patients with no known coronary artery disease. J Nucl Med 2006;47: 51-8. (Pubitemid 46768512)
8. Berman D, Kang X, Gransar H, Gerlach J, Friedman J, Hayes S, et al. Quantitative assessment of myocardial perfusion abnormality on SPECT myocardial perfusion imaging is more reproducible than expert visual analysis. J Nucl Cardiol 2009;16:45-53.
9. Xu Y, Hayes S, Ali I, Ruddy TD, Wells RG, Berman DS, et al. Automatic and visual reproducibility of perfusion and function measures for myocardial perfusion SPECT. J Nucl Cardiol 2010;17: 1050-7.
10. Santana CA, Folks RD, Garcia EV, Verdes L, Sanyal R, Hainer J, et al. Quantitative (82)Rb PET/CT: Development and validation of myocardial perfusion database. J Nucl Med 2007;48:1122-8. (Pubitemid 47052652)
11. Mawlawi O, Podoloff DA, Kohlmyer S, Williams JJ, Stearns CW, Culp RF, et al. Performance characteristics of a newly developed PET/CT scanner using NEMA standards in 2D and 3D modes. J Nucl Med 2004;45:1734-42. (Pubitemid 47618484)
12. Slomka P, Dorbala S, Berman D, Gerlacj J, Germano G, Di Carli M. Automated quantification and normal limits for myocardial perfusion stress/rest Rb-82 PET/CT. J Nucl Med 2009;50:1164.
13. Slomka P, Nishina H, Berman D, Akincioglu C, Abidov A, Friedman J, et al. Automated quantification of myocardial perfusion SPECT using simplified normal limits. J Nucl Cardiol 2005; 12:66-77.
14. Diamond G, Forrester J. Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease. N Engl J Med 1979; 300:1350-8. (Pubitemid 9198112)
15. Nakazato R, Tamarappoo BK, Kang X, Wolak A, Kite F, Hayes SW, et al. Quantitative upright-supine high-speed SPECT myocardial perfusion imaging for detection of coronary artery disease: Correlation with invasive coronary angiography. J Nucl Med 2010;51: 1724-31.
16. Jonsson C, Odh R, Schnell P, Larsson S. A comparison of the imaging properties of a 3-and 4-ring biograph PET scanner using a novel extended NEMA phantom. IEEE Nucl Sci Symp Conf Rec 2007;4:2865-7.
17. Townsend D, Jakoby B, Long M, Carr C, Hubner K, Guglielmo C, et al. Performance and clinical workflow of a new combined PET/CT scanner. J Nucl Med 2007;48:437P.
18. Cerqueira MD, Verani MS, Schwaiger M, Heo J, Iskandrian AS. Safety profile of adenosine stress perfusion imaging: Results from the Adenoscan Multicenter Trial Registry. J Am Coll Cardiol 1994;23:384-9. (Pubitemid 24049369)
19. Watson C, Hayden C, Casey M, Hamill J, Bendriem B. Prompt gamma correction for improved quantification in 82Rb PET. J Nucl Med 2008;49:64P.
20. Slomka P, Le Meunier L, Hayes S, Acampa W, Oba M, Haemer G, et al. Comparison of myocardial perfusion 82Rb PET performed with CT- and transmission CT-based attenuation correction. J Nucl Med 2008;49:1992-8.
21. Germano G, Kiat H, Kavanagh PB, Moriel M, Mazzanti M, Su HT, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med 1995;36:2138-47.
22. Cerqueira M, Weissman N, Dilsizian V, Jacobs A, Kaul S, Laskey W, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation 2002;105:539-42. (Pubitemid 34262671)
23. Mazzanti M, Germano G, Kiat H, Kavanagh PB, Alexanderson E, Friedman JD, et al. Identification of severe and extensive coronary artery disease by automatic measurement of transient ischemic dilation of the left ventricle in dual-isotope myocardial perfusion SPECT. J Am Coll Cardiol 1996;27:1612-20. (Pubitemid 26198012)
24. Slomka P, Nishina H, Berman D, Kang X, Friedman J, Hayes S, et al. Automatic quantification of myocardial perfusion stress-rest change: A new measure of ischemia. J Nucl Med 2004;45:183-91. (Pubitemid 47618635)
25. Berman D, Kang X, Hayes S, Friedman J, Cohen I, Abidov A, et al. Adenosine myocardial perfusion single-photon emission computed tomography in women compared with men. Impact of diabetes mellitus on incremental prognostic value and effect on patient management. J Am Coll Cardiol 2003;41:1125-33. (Pubitemid 36384899)
26. Shaw L, Berman D, Maron D, Mancini G, Hayes S, Hartigan P, et al. Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: Results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy. Circulation 2008;117:1283-91. (Pubitemid 351365675)
27. Grossman GB, Garcia EV, Bateman TM, Heller GV, Johnson LL, Folks RD, et al. Quantitative Tc-99m sestamibi attenuation-corrected SPECT: Development and multicenter trial validation of myocardial perfusion stress gender-independent normal database in an obese population. J Nucl Cardiol 2004;11:263-72. (Pubitemid 38950251)
28. Sharir T, Kang X, Germano G, Bax J, Shaw L, Gransar H, et al. Prognostic value of poststress left ventricular volume and ejection fraction by gated myocardial perfusion SPECT in women and men: Gender-related differences in normal limits and outcomes. J Nucl Cardiol 2006;13:495-506. (Pubitemid 44226071)
29. Beanlands RS, Chow BJ, Dick A, Friedrich MG, Gulenchyn KY, Kiess M, et al. CCS/CAR/CANM/CNCS/CanSCMR joint position statement on advanced noninvasive cardiac imaging using positron emission tomography, magnetic resonance imaging and multidetector computed tomographic angiography in the diagnosis and evaluation of ischemic heart disease - executive summary. Can J Cardiol 2007;23:107-19. (Pubitemid 46655426)
30. Bravo PE, Chien D, Javadi M, Merrill J, Bengel FM. Reference ranges for LVEF and LV volumes from electrocardiographically gated 82Rb cardiac PET/CT using commercially available software. J Nucl Med 2010;51:898-905.
31. Slomka P, Germano G, Kavanagh P, Javadi M, Berman D, Bengel F. Evaluation of a new automatic algorithm for quantification of ECG-gated 82Rb cardiac PET. J Nucl Med 2009;50:1167.
32. Cullom S, Bateman T, Volker L, Hsu B, McGhie I, Case J. Transient ischemic dilation in response to dipyridamole stress with Rubidium- 82 myocardial perfusion PET: Quantitative comparison of lowlikelihood and CAD populations. J Nucl Med 2007;48:106P.
33. Sharir T, Berman DS, Waechter PB, Areeda J, Kavanagh PB, Gerlach J, et al. Quantitative analysis of regional motion and thickening by gated myocardial perfusion SPECT: Normal heterogeneity and criteria for abnormality. J Nucl Med 2001;42:1630-8. (Pubitemid 33131321)
34. Parkash R, deKemp RA, Ruddy TD, Kitsikis A, Hart R, Beauchesne L, et al. Potential utility of rubidium 82 PET quantification in patients with 3-vessel coronary artery disease. J Nucl Cardiol 2004;11:440-9. (Pubitemid 39115288)
35. Klein R, Beanlands RS, deKemp RA. Quantification of myocardial blood flow and flow reserve: Technical aspects. J Nucl Cardiol 2010;17:555-70.
36. Knesaurek K, Machac J, Krynyckyi BR, Almeida OD. Comparison of 2-dimensional and 3-dimensional 82Rb myocardial perfusion PET imaging. J Nucl Med 2003;44:1350-6. (Pubitemid 39655196)
37. Votaw JR, White M. Comparison of 2-dimensional and 3-dimensional cardiac 82Rb PET studies. J Nucl Med 2001;42:701-6. (Pubitemid 32453456)
38. Tarantola G, Zito F, Gerundini P. PET instrumentation and reconstruction algorithms in whole-body applications. J Nucl Med 2003;44:756-69. (Pubitemid 39655211)