Clinical Practice Guidelines for Assessment and Treatment of Transsexualism. SEEN Identity and Sexual Differentiation Groupd (GIDSEEN);Guías de práctica clínica para la valoración y tratamiento de la transexualidad. Grupo de Identidad y Diferenciación Sexual de la SEEN (GIDSEEN)*(anexo 1)

Endocrinologia y Nutricion

Volumn 59, Issue 6, 2012, Pages 367-382

  Moreno Pérez, Óscar ^a   Esteva De Antonio, Isabel ^b  

^a HOSPITAL GENERAL UNIVERSITARIO DE ALICANTE   (Spain)

^b HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

Author keywords

Gender dysphoria; Practice guideline; Transsexualism; Treatment

Indexed keywords

ARTICLE; COMORBIDITY; ENDOCRINOLOGY; HEALTH CARE; HORMONAL THERAPY; HUMAN; MENTAL DISEASE; PATIENT CARE; PRACTICE GUIDELINE; PSYCHOTHERAPY; QUALITY OF LIFE; SEX DIFFERENTIATION; SEX REASSIGNMENT; TRANSSEXUALISM;

FEMALE; HUMANS; MALE; TRANSSEXUALISM;

EID: 84863459790     PISSN: 15750922     EISSN: 15792021     Source Type: Journal    
DOI: 10.1016/j.endonu.2012.02.001     Document Type: Article

References (65)

1. The World Professional Association for Transgender Health (2011). Standards of Care for the Health of Transsexual, Transgender, and Gender Nonconforming People (7th version). [consultado 1/10/2011]Diponible en: (). http://www.wpath.org/.
2. Gómez-Gil E, Esteva de Antonio I. Ser transexual. Barcelona: Editorial Glosa; 2006 (ISBN 84-7429-267-0).
3. Esteva de Antonio I, Almaraz Almaraz MC, González Molero I, Tapia Guerrero MJ. Transexualismo. En: Manual del Residente de Endocrinología y Nutrición. Editado por la Sociedad Española de Endocrinología y Nutrición, año 2009. ISBN 978-84-692-1374-2.
4. Wilson P., Sharp C., Carr S. The prevalence of gender dysphoria in Scotland: a primary care study. Br J Gen Pract 1999, 49:991-992.
5. Bakker A., Van Kesteren P.J., Gooren L.J., Bezemer P.D. The prevalence of transsexualism in The Netherlands. Acta Psychiatr Scand 1993, 87:237-238.
6. Gender Identity Research and Education Society Article of Gender Variance (dysphoria). [consultado 1/10/2011]. Disponible en http://www.gires.org.uk/.
7. Esteva I., Gonzalo M., Yahyaoui R., Domínguez M., Bergero T., Giraldo F., et al. Epidemiología de la transexualidad en Andalucía, atención especial al grupo de adolescentes. Cuad Med Psicosom 2006, 78:65-70.
8. Gómez-Gil E., Esteva I., Almaraz M.C., Godás T., Halperin I., Soriguer F. Equipos de Identidad de Género de Andalucía y Cataluña. Demanda de atención sanitaria en las unidades de identidad de género de Andalucía y Cataluña durante la década 2000 a 2009. Rev Clin Esp 2011, 211:233-239.
9. Gómez-Gil E., Trilla García A., Godás Sieso T., Halperin Rabinovich I., Puig Domingo M., Vidal Hagemeijer A., et al. Estimación de la prevalencia, incidencia y razón de sexos del transexualismo en Cataluña según la demanda asistencial. Actas Esp Psiquiatr 2006, 34:295-302.
10. Landen M., Walinder J., Hambert G., Lundstrom B. Factors predictive of regret in sex reassignment. Acta Psychiatr Scand 1998, 97:284-289.
11. Gooren L.J., Giltay E.J., Bunck M.C. Long-term treatment of transsexuals with cross-sex hormones: extensive personal experience. J Clin Endocrinol Metab 2008, 93:19-25.
12. Ruble D.N., Martin C.L., Berenbaum S.A. Gender development. Handbook of Child Psychology 2006, 3:858-932. John Wiley & Sons, New York, NY. 6th ed.
13. Zucker K.J. Gender identity development and issues. Child Adolesc Psychiatric Clin N Am 2004, 13:551-568.
14. Knafo A., Lervolono A.C., Plomin R. Masculine girls and feminine boys: Genetic and environmental contributions to atypical gender development in early childhood. J Pers Soc Psychol 2005, 88:400-412.
15. Gooren L. The biology of human psychosexual differentiation. Horm Behav 2006, 50:589-601.
16. Bocklandt S., Vilain E. Sex differences in brain and behavior: hormones versus genes. Adv Genet 2007, 59:245-266.
17. Hembree W.C., Cohen-Kettenis P., Delemarre H.A., Gooren L.J., Meyer W.J., Spack N.P., et al. Endocrine treatment of transsexual persons: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2009, 94:3132-3154.
18. Cano G., Bergero T. Intervención psicológica en una unidad de trastornos de la identidad de género: un desafío sanitario. El psicólogo en el ámbito hospitalario 2003, Desclèe de Brouwer, Madrid. 2a. ed. E. Remor, P. Arranz, S. Ulla (Eds.).
19. Hurtado Murillo F. La evaluación diagnóstica y el abordaje psicológico de la transexualidad. Sexología Integral 2009, 6:86.
20. Hurtado Murillo F., Gómez Balaguer M., Donat Colomer F. Transexualismo mujer a hombre: perfil psicológico y calidad de vida. Sexología Integral 2007, 4:140-142.
21. Hurtado Murillo F., Gómez Balaguer M., Donat Colomer F. Transexualidad y salud mental. Rev Psicopat Psicol Clin 2007, 2:43-57.
22. Weinrich J.D., Atkinson J.H., McCutchan J.A., Grant I. Is gender dysphoria dysphoric. Elevated depression and anxiety in gender dysphoric and nondysphoric homosexual and bisexual men in a HIV sample. HNRC Group. Arch Sex Behav 1995, 24:55-72.
23. Levine S.B. Psychiatric diagnosis of patients requesting sex reassignment surgery. J Sex Marit Therapy 1980, 6:164-173. Fall.
24. Hepp U., Kraemer B., Schnyder U., Miller N., Delsignore A. Psychatric comorbidity in gender identity disorder. J Psychsom Res 2005, 58:259-261.
25. Olsson S.E., Moller A. Regret after sex reassignment surgery in a male-to-female transsexual: a long-term follow-up. Arch Sex Behav 2006, 35:501-506.
26. Sánchez Planell L. Psychophatological disorders in intersexual states. Textbook intersexual states. Disorders of sex differentation 1994, 369-378. Ediciones Doyma, Barcelona. J. Martínez-Mora (Ed.).
27. Michel A., Mormont C., Legros J.J. A psycho-endocrinological overview of transsexualism. Eur J Endocrinol 2001, 145:365-376.
28. Herbst J.H., Jacobs E.D., Finlayson T.J., McKleroy V.S., Neumann M.S., Crepaz N. HIV/AIDS Prevention Research Synthesis Team. Estimating HIV prevalence and risk behaviors of transgender persons in the United States: a systematic review. AIDS Behav 2008, 12:1-7.
29. Moreno-Pérez O. Transexualidad: control del tratamiento. En: Función androgénica en el laboratorio. Editado por: Comité de Comunicación de la Sociedad Española de Bioquímica Clínica y Patología Molecular, 2010 (ISBN: 84-89975-40-X).
30. Moore E., Wisniewski A., Dobs A. Endocrine treatment of transsexual people: a review of treatment regimens, outcomes, and adverse effects. J Clin Endocrinol Metab 2003, 88:3467-3473.
31. Toorians A.W., Thomassen M.C., Zweegman S. Venous thrombosis and changes of hemostatic variables during cross-sex hormone treatment in transsexual people. J Clin Endocrinol Metab 2003, 88:5723-5729.
32. Dittrich R., Binder H., Cupisti S., Hoffmann I.Estimating HIV prevalence and risk behaviors of transgender persons in the United States: a systematic review., et al. Endocrine treatment of male-to-female transsexuals using gonadotropin-releasing hormone agonist. Exp Clin Endocrinol Diabetes 2005, 113:586-592.
33. Ettner R., Monstrey S., Eyler E. Principles of transgender medicine and surgery 2007, Haworth Press, New York.
34. Levy A., Crown A., Reid R. Endocrine intervention for transsexuals. Clin Endocrinol (Oxf) 2003, 59:409-418.
35. Gooren L.J., Giltay E.J. Review of studies of androgen treatment of female-to-male transsexuals: effects and risks of administration of androgens to females. J Sex Med 2008, 5:765-776.
36. Van Kesteren P., Lips P., Gooren L.J., Beckmann M.W., Mueller A. Long-term follow-up of bone mineral density and bone metabolism in transsexuals treated with cross-sex hormones. Clin Endocrinol (Oxf) 1998, 48:347-354.
37. Ruetsche A.G., Kneubuehl R., Birkhaeuser M.H. Cortical and trabecular bone mineral density in transsexuals after long-term cross-sex hormonal treatment: a cross-sectional study. Osteoporos Int 2005, 16:791-798.
38. Vidales A., Haro-Mora J., Yahyaoui R. Metabolic syndrome incidence in a transgender Spanish population under cross sex treatment: a three years follow-up. Journal of Diabetes 2011, 3(s1):94. abstract.
39. Mueller A., Gooren L. Hormone-related tumors in transsexuals receiving treatment with cross-sex hormones. Eur J Endocrinol 2008, 159:197-202.
40. Anderson G.L., Limacher M., Assaf A.R., Beresford S.A., Black H., Bassford T. Women's Health Initiative Steering Committee. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA 2004, 291:1701-1712.
41. Schoemaker M.J., Swerdlow A.J., Higgins C.D., Wright A.F., Jacobs P.A., et al. Clinical Cytogenetics Group. Cancer incidence in women with Turner syndrome in Great Britain: a national cohort study. Lancet Oncol 2008, 9:239-246. UK Clinical Cytogenetics Group.
42. Asscheman H., Gooren L.J., Assies J., Smits J.P., de Slegte R. Prolactin levels and pituitary enlargement in hormone-treated male-to-female transsexuals. Clin Endocrinol (Oxf) 1988, 28:583-588.
43. Garcia-Malpartida K., Martin-Gorgojo A., Rocha M., Gómez-Balaguer M., Hernandez-Mijares A. Prolactinoma induced by estrogen and cyproterona acetate in a male-to-female transsexual. Fertil Steril 2010, 94:1097. e13-5.
44. Futterweit W., Deligdisch L. Histopathological effects of exogenously administered testosterone in 19 female to male transsexuals. J Clin Endocrinol Metab 1986, 62:16-21.
45. Becerra A., De Luis D.A., Piédrola G. Morbilidad en pacientes transexuales con autotratamiento hormonal para cambio de sexo. Med Clin (Barc) 1999, 113:484-487.
46. Van Kesteren P.J., Asscheman H., Megens J.A., Gooren L.J. Mortality and morbidity in transsexual subjects treated with cross-sex hormones. Clin Endocrinol (Oxf) 1997, 47:337-342.
47. Elbers J.M., Giltay E.J., Teerlink T., Scheffer P.G., Asscheman H., Seidell J.C., et al. Effects of sex steroids on components of the insulin resistance syndrome in transsexual subjects. Clin Endocrinol (Oxf) 2003, 58:562-571.
48. Bhasin S., Cunningham G.R., Hayes F., Matsumoto A.M., Snyder P.J., Swerdloff R.S., et al. Testosterone therapy in adult men with androgen deficiency syndromes. J Clin Endocrinol Metab 2006, 91:1995-2010.
49. Laughlin G.A., Barrett-Connor E., Bergstrom J. Low serum testosterone and mortality in older men. J Clin Endocrinol Metab 2008, 93:68-75.
50. Khaw K.T., Dowsett M., Folkerd E., Bingham S., Wareham N., Luben R., et al. Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study. Circulation 2007, 116:2694-2701.
51. Turgeon J.L., Carr M.C., Maki P.M., Mendelsohn M.E., Wise P.M. Complex actions of sex steroids in adipose tissue, the cardiovascular system, and brain: Insights from basic science and clinical studies. Endocr Rev 2006, 27:575-605.
52. DeFronzo R.A. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 1988, 37:667-687.
53. Yahyaoui R., Esteva I., Haro-Mora J.J., Almaraz M.C., Morcillo S., Rojo-Martínez G., et al. Effect of long-term administration of cross-sex hormone therapy on serum and urinary uric acid in transsexual persons. J Clin Endocrinol Metab 2008, 93:2230-2233.
54. Drummond K.D., Bradley S.J., Peterson-Badali M., Zucker K.J. A follow-up study of girls with gender identity disorder. Dev Psychol 2008, 44:34-45.
55. Wallien M.S.C., Cohen-Kettenis P.T. Psychosexual outcome of gender dysphoric children. Am J Child Adolesc Psychiatry 2008, 47:1413-1423.
56. Delemarre-Van de Waal H.A., Cohen-Kettenis P.T. Clinical management of gender identity disorder in adolescents: a protocol on psychological and paediatric endocrinology aspects. Eur J Endocrinol 2006, 155:S131-S137.
57. Hurtado Murillo F., Gómez Balaguer M., Donat Colomer F. Transexualismo hombre a mujer: intervención en adolescentes. Sexología Integral 2008, 5:85-87.
58. Tugnet N., Goddard J.C., Vickery R.M., Khoosal D., Terry T.R. Current management of male-to-female gender identity disorder in the UK. Postgrad Med J 2007, 83:638-642.
59. Kreukels B.P.C., Cohen-Kettenis P.T. Puberty suppression in gender identity disorder: the Amsterdam experience. Nat Rev Endocrinol 2011, 7:466-472. published online 17 May 2011; doi:10.1038/nrendo.2011.78.
60. Giraldo F., Esteva I., Bergero T., Cano G., González C., Salinas P., et al. Corona Glans Clitoroplasty and Urethropreputial Vestibuloplasty in Male-to-Female Transsexuals: The vulval aesthetic refinement by the Andalusia Gender Team [IDEAS AND INNOVATIONS]. Plast Reconstr Surg 2004, 114:1543-1550. Andalusia Gender Team.
61. Dizon D.S., Tejada-Berges T., Koelliker S., Steinhoff M., Granai C.O. Ovarian cancer associated with testosterone supplementation in a female-to-male transsexual patient. Gynecol Obstet Invest 2006, 62:226-228.
62. Gómez-Gil E., Esteva I., Almaraz M.C., Pasaro E., Segovia S., Guillamon A. Familiality of gender identity disorder in non-twin siblings. Arch Sex Behav 2010, 39:546-552.
63. Gómez-Gil E., Esteva I., Carrasco R., Almaraz M.C., Pasaro E., Salamero M., et al. Birth Order and ratio of brothers to sisters in spanish transsexuals. Arch Sex Behav 2010, 40:505-510.
64. Gómez-Gil E, Gómez A, Cañizares S, Guillamón A, Rametti G, Esteva I, et al. Clinical utility of the Bem Sex Role Inventory (BSRI) in the Spanish transsexual and non transsexual population. J Person Assesm (in press 2011).
65. Esteva de Antonio I, Gómez-Gil E, Almaraz MA, Martínez-Tudela J, Bergero T, Olveira G, et al y Grupo GIDSEEN. Organización de la asistencia a la transexualidad en el Sistema Sanitario Público Español.(Organization of the assistance to transsexuality in the Spanish Public Health System). Gac Sanit (in press 2011).