In vivo tracking of mesechymal stem cells using fluorescent nanoparticles in an osteochondral repair model

Molecular Therapy

Volumn 20, Issue 7, 2012, Pages 1434-1442

  Lee, Jong Min ^a   Kim, Byung Soo ^b   Lee, Haeshin ^c   Im, Gun Il ^a  

^a Dongguk University Ilsan Hospital   (South Korea)

^b Seoul National University   (South Korea)

^c Korea Advanced Institute of Science & Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE NANOPARTICLE; HEPARIN; HEPARIN CONJUGATED FIBRIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NANOPARTICLE; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; BONE DEFECT; BONE REMODELING; CARTILAGE; CELL COUNT; CELL DENSITY; CELL LABELING; CELL MIGRATION; CELL TRACKING; CHEMOTAXIS; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN SECRETION; RAT;

RATTUS;

EID: 84863455876     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2012.60     Document Type: Conference Paper

References (47)

1. Alhadlaq, A and Mao, JJ (2003). Tissue-engineered neogenesis of human-shaped mandibular condyle from rat mesenchymal stem cells. J Dent Res 82: 951-956. (Pubitemid 41713810)
2. Rahfoth, B, Weisser, J, Sternkopf, F, Aigner, T, von der Mark, K and Brer, R (1998). Transplantation of allograft chondrocytes embedded in agarose gel into cartilage defects of rabbits. Osteoarthr Cartil 6: 50-65. (Pubitemid 28160884)
3. Steinert, A, Weber, M, Dimmler, A, Julius, C, Schze, N, nh, U et al. (2003). Chondrogenic differentiation of mesenchymal progenitor cells encapsulated in ultrahigh-viscosity alginate. J Orthop Res 21: 1090-1097. (Pubitemid 37322390)
4. Li, WJ, Tuli, R, Okafor, C, Derfoul, A, Danielson, KG, Hall, DJ et al. (2005). A threedimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells. Biomaterials 26: 599-609. (Pubitemid 38988302)
5. Benya, PD, Padilla, SR and Nimni, ME (1978). Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture. Cell 15: 1313-1321. (Pubitemid 9109690)
6. Lefebvre, V, Peeters-Joris, C and Vaes, G (1990). Production of collagens, collagenase and collagenase inhibitor during the dedifferentiation of articular chondrocytes by serial subcultures. Biochim Biophys Acta 1051: 266-275. (Pubitemid 20077668)
7. Beiser, IH and Kanat, IO (1990). Subchondral bone drilling: a treatment for cartilage defects. J Foot Surg 29: 595-601.
8. Shapiro, F, Koide, S and Glimcher, MJ (1993). Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J Bone Joint Surg Am 75: 532-553. (Pubitemid 23171742)
9. Wei, X, Gao, J and Messner, K (1997). Maturation-dependent repair of untreated osteochondral defects in the rabbit knee joint. J Biomed Mater Res 34: 63-72. (Pubitemid 26425219)
10. rter, B, Grace, B, Seitz, O, Seifried, E and Henschler, R (2005). Induction and detection of human mesenchymal stem cell migration in the 48-well reusable transwell assay. Stem Cells Dev 14: 231-235. (Pubitemid 40677396)
11. Son, BR, Marquez-Curtis, LA, Kucia, M, Wysoczynski, M, Turner, AR, Ratajczak, J et al. (2006). Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases. Stem Cells 24: 1254-1264. (Pubitemid 44464694)
12. Ponte, AL, Marais, E, Gallay, N, Langonn A, Delorme, B, Hault, O et al. (2007). The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells 25: 1737-1745. (Pubitemid 47121852)
13. Forte, G, Minieri, M, Cossa, P, Antenucci, D, Sala, M, Gnocchi, V et al. (2006). Hepatocyte growth factor effects on mesenchymal stem cells: proliferation, migration, and differentiation. Stem Cells 24: 23-33.
14. Zhang, F, Tsai, S, Kato, K, Yamanouchi, D, Wang, C, Rafii, S et al. (2009). Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrowderived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells. J Biol Chem 284: 17564-17574.
15. Park, JS, Yang, HN, Woo, DG, Jeon, SY and Park, KH (2011). Chondrogenesis of human mesenchymal stem cells in fibrin constructs evaluated in vitro and in nude mouse and rabbit defects models. Biomaterials 32: 1495-1507.
16. Kim, HS, Cho, HR, Choi, SH, Woo, JS and Moon, WK (2010). In vivo imaging of tumor transduced with bimodal lentiviral vector encoding human ferritin and green fluorescent protein on a 1.5T clinical magnetic resonance scanner. Cancer Res 70: 7315-7324.
17. Huang, M, Chen, Z, Hu, S, Jia, F, Li, Z, Hoyt, G et al. (2009). Novel minicircle vector for gene therapy in murine myocardial infarction. Circulation 120 (suppl. 11): S230-S237.
18. Yang, Q, Peng, J, Guo, Q, Huang, J, Zhang, L, Yao, J et al. (2008). A cartilage ECMderived 3-D porous acellular matrix scaffold for in vivo cartilage tissue engineering with PKH26-labeled chondrogenic bone marrow-derived mesenchymal stem cells. Biomaterials 29: 2378-2387.
19. Shah, BS, Clark, PA, Moioli, EK, Stroscio, MA and Mao, JJ (2007). Labeling of mesenchymal stem cells by bioconjugated quantum dots. Nano Lett 7: 3071-3079. (Pubitemid 350132932)
20. Lu, CW, Hung, Y, Hsiao, JK, Yao, M, Chung, TH, Lin, YS et al. (2007). Bifunctional magnetic silica nanoparticles for highly efficient human stem cell labeling. Nano Lett 7: 149-154. (Pubitemid 46225844)
21. He, G, Zhang, H, Wei, H, Wang, Y, Zhang, X, Tang, Y et al. (2007). In vivo imaging of bone marrow mesenchymal stem cells transplanted into myocardium using magnetic resonance imaging: a novel method to trace the transplanted cells. Int J Cardiol 114: 4-10. (Pubitemid 44802890)
22. Park, KS, Tae, J, Choi, B, Kim, YS, Moon, C, Kim, SH et al. (2010). Characterization, in vitro cytotoxicity assessment, and in vivo visualization of multimodal, RITClabeled, silica-coated magnetic nanoparticles for labeling human cord blood-derived mesenchymal stem cells. Nanomedicine 6: 263-276.
23. Ding, J, Ghali, O, Lencel, P, Broux, O, Chauveau, C, Devedjian, JC et al. (2009). TNF-alpha and IL-1beta inhibit RUNX2 and collagen expression but increase alkaline phosphatase activity and mineralization in human mesenchymal stem cells. Life Sci 84: 499-504.
24. Cassiede, P, Dennis, JE, Ma, F and Caplan, AI (1996). Osteochondrogenic potential of marrow mesenchymal progenitor cells exposed to TGF-beta 1 or PDGF-BB as assayed in vivo and in vitro. J Bone Miner Res 11: 1264-1273. (Pubitemid 26282527)
25. Lohmann, CH, Schwartz, Z, Niederauer, GG, Carnes, DL Jr, Dean, DD and Boyan, BD (2000). Pretreatment with platelet derived growth factor-BB modulates the ability of costochondral resting zone chondrocytes incorporated into PLA/PGA scaffolds to form new cartilage in vivo. Biomaterials 21: 49-61.
26. Shure, D, Senior, RM, Griffin, GL and Deuel, TF (1992). PDGF AA homodimers are potent chemoattractants for fibroblasts and neutrophils, and for monocytes activated by lymphocytes or cytokines. Biochem Biophys Res Commun 186: 1510-1514. (Pubitemid 23189495)
27. Ricono, JM, Wagner, B, Gorin, Y, Arar, M, Kazlauskas, A, Choudhury, GG et al. (2009). PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA. Am J Physiol Renal Physiol 296: F406-F417.
28. Eriksson, A, Siegbahn, A, Westermark, B, Heldin, CH and Claesson-Welsh, L (1992). PDGF alpha-and beta-receptors activate unique and common signal transduction pathways. EMBO J 11: 543-550.
29. Mishima, Y and Lotz, M (2008). Chemotaxis of human articular chondrocytes and mesenchymal stem cells. J Orthop Res 26: 1407-1412.
30. Ringe, J, Strassburg, S, Neumann, K, Endres, M, Notter, M, Burmester, GR et al. (2007). Towards in situ tissue repair: human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2. J Cell Biochem 101: 135-146. (Pubitemid 46652579)
31. Fox, JM, Chamberlain, G, Ashton, BA and Middleton, J (2007). Recent advances into the understanding of mesenchymal stem cell trafficking. Br J Haematol 137: 491-502. (Pubitemid 46817339)
32. Fiedler, J, Brill, C, Blum, WF and Brenner, RE (2006). IGF-I and IGF-II stimulate directed cell migration of bone-marrow-derived human mesenchymal progenitor cells. Biochem Biophys Res Commun 345: 1177-1183. (Pubitemid 43776505)
33. Toh, WS, Lee, EH, Guo, XM, Chan, JK, Yeow, CH, Choo, AB et al. (2010). Cartilage repair using hyaluronan hydrogel-encapsulated human embryonic stem cell-derived chondrogenic cells. Biomaterials 31: 6968-6980.
34. Wang, W, Li, B, Yang, J, Xin, L, Li, Y, Yin, H et al. (2010). The restoration of fullthickness cartilage defects with BMSCs and TGF-beta 1 loaded PLGA/fibrin gel constructs. Biomaterials 31: 8964-8973.
35. Emans, PJ, van Rhijn, LW, Welting, TJ, Cremers, A, Wijnands, N, Spaapen, F et al. (2010). Autologous engineering of cartilage. Proc Natl Acad Sci USA 107: 3418-3423.
36. Matsumoto, T, Cooper, GM, Gharaibeh, B, Meszaros, LB, Li, G, Usas, A et al. (2009). Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1. Arthritis Rheum 60: 1390-1405.
37. Zhang, X, Mitsuru, A, Igura, K, Takahashi, K, Ichinose, S, Yamaguchi, S et al. (2006). Mesenchymal progenitor cells derived from chorionic villi of human placenta for cartilage tissue engineering. Biochem Biophys Res Commun 340: 944-952. (Pubitemid 43053919)
38. Yang, HS, La, WG, Bhang, SH, Jeon, JY, Lee, JH and Kim, BS (2010). Heparinconjugated fibrin as an injectable system for sustained delivery of bone morphogenetic protein-2. Tissue Eng Part A 16: 1225-1233.
39. Howard, DB, Powers, K, Wang, Y and Harvey, BK (2008). Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro. Virology 372: 24-34. (Pubitemid 351215455)
40. Banin, E, Obolensky, A, Piontek, E, Falk, H, Pikarsky, E, Pe'er, J et al. (2003). Gene delivery by viral vectors in primary cultures of lacrimal gland tissue. Invest Ophthalmol Vis Sci 44: 1529-1533. (Pubitemid 36378578)
41. Stone, D, David, A, Bolognani, F, Lowenstein, PR and Castro, MG (2000). Viral vectors for gene delivery and gene therapy within the endocrine system. J Endocrinol 164: 103-118. (Pubitemid 30114658)
42. Greenbaum, L, Rothmann, C, Lavie, R and Malik, Z (2000). Green fluorescent protein photobleaching: a model for protein damage by endogenous and exogenous singlet oxygen. Biol Chem 381: 1251-1258. (Pubitemid 32094437)
43. Li, SC, Tachiki, LM, Luo, J, Dethlefs, BA, Chen, Z and Loudon, WG (2010). A biological global positioning system: considerations for tracking stem cell behaviors in the whole body. Stem Cell Rev 6: 317-333.
44. Hingtgen, SD, Kasmieh, R, van de Water, J, Weissleder, R and Shah, K (2010). A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy. Stem Cells 28: 832-841.
45. Kim, JS, Yoon, TJ, Yu, KN, Kim, BG, Park, SJ, Kim, HW et al. (2006). Toxicity and tissue distribution of magnetic nanoparticles in mice. Toxicol Sci 89: 338-347. (Pubitemid 43013783)
46. Kim, YJ, Kim, HJ and Im, GI (2008). PTHrP promotes chondrogenesis and suppresses hypertrophy from both bone marrow-derived and adipose tissue-derived MSCs. Biochem Biophys Res Commun 373: 104-108.
47. van den Borne, MP, Raijmakers, NJ, Vanlauwe, J, Victor, J, de Jong, SN, Bellemans, J et al. (2007). International Cartilage Repair Society (ICRS) and Oswestry macroscopic cartilage evaluation scores validated for use in Autologous Chondrocyte Implantation (ACI) and microfracture. Osteoarthr Cartil 15: 1397-1402. (Pubitemid 350048561)