Sample size adaptation in fixed-dose combination drug trial

Journal of Biopharmaceutical Statistics

Volumn 22, Issue 4, 2012, Pages 679-686

  James Hung, H M ^a   Wang, Sue Jane ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Interim analysis; Min test; Nuisance parameter; Sample size reallocation

Indexed keywords

PLACEBO; UNCLASSIFIED DRUG;

ANALYTICAL ERROR; CLINICAL TRIAL (TOPIC); DRUG DOSAGE FORM; FIXED DOSE DRUG COMBINATION; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; PRIORITY JOURNAL; REVIEW; SAMPLE SIZE; STATISTICAL PARAMETERS; STUDY DESIGN;

ALGORITHMS; BIOMETRY; CLINICAL TRIALS AS TOPIC; DRUG THERAPY, COMBINATION; FACTOR ANALYSIS, STATISTICAL; HUMANS; MODELS, STATISTICAL; RESEARCH DESIGN; SAMPLE SIZE;

EID: 84863441154     PISSN: 10543406     EISSN: 15205711     Source Type: Journal    
DOI: 10.1080/10543406.2012.676533     Document Type: Review

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