Stroke in children with posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities (PHACE) syndrome: A systematic review of the literature

Stroke

Volumn 43, Issue 6, 2012, Pages 1672-1674

  Siegel, Dawn H ^a   Tefft, Kimberly A ^b   Kelly, Teresa ^a   Johnson, Craig ^a   Metry, Denise ^c   Burrows, Patricia ^d   Pope, Elena ^e   Cordisco, Maria ^f   Holland, Kristen E ^a   Maheshwari, Mohit ^a   Keith, Phillip ^a   Garzon, Maria ^j   Hess, Christopher ^g   Frieden, Ilona J ^h   Fullerton, Heather J ⁱ   Drolet, Beth A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f HOSPITAL DE PEDIATRÍA PROF DR JUAN P GARRAHAN   (Argentina)

^g Och Spine at New York Presbyterian Hospitals   (United States)

^h Departments of Radiology and Biomedical Imaging   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j NONE

more..

Author keywords

arterial ischemic syndrome; hemangioma; Pascual Castroviejo Type II syndrome; PHACE syndrome; PHACES association; propranolol

Indexed keywords

AMLODIPINE; CORTICOSTEROID; HYDROCHLOROTHIAZIDE PLUS SPIRONOLACTONE; INTERFERON; NADOLOL; PROPRANOLOL; VINCRISTINE;

AORTA ANEURYSM; AORTA ANOMALY; AORTA COARCTATION; ARTERY DISEASE; ARTERY MALFORMATION; CARDIOVASCULAR RISK; CLINICAL FEATURE; COHORT ANALYSIS; CONGENITAL HEART MALFORMATION; DRUG EXPOSURE; EYE MALFORMATION; HEMANGIOMA; HUMAN; HYPERTENSION; MULTIPLE MALFORMATION SYNDROME; ONSET AGE; PHACE SYNDROME; POSTERIOR FOSSA; PRIORITY JOURNAL; REVIEW; SACCULAR ANEURYSM; SKULL MALFORMATION; STROKE; SYSTEMATIC REVIEW;

ABNORMALITIES, MULTIPLE; ANGIOGRAPHY; AORTIC COARCTATION; BRAIN; COHORT STUDIES; EYE ABNORMALITIES; FEMALE; HEART DEFECTS, CONGENITAL; HEMANGIOMA; HUMANS; INFANT; MALE; RISK FACTORS; STROKE; SYNDROME;

EID: 84863405033     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.112.650952     Document Type: Review

References (15)

1. Frieden IJ, Reese V, Cohen D. PHACE syndrome. The association of posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities. Arch Dermatol. 1996;132:307-311.
2. Bernard TJ, Manco-Johnson MJ, Lo W, Mackay MT, Ganesan V, Deveber G, et al. Towards a consensus-based classification of childhood arterial ischemic stroke. Stroke. 2012;43:371-377.
3. Kirton A, Shroff M, Pontigon AM, deVeber G. Risk factors and presentations of periventricular venous infarction vs arterial presumed perinatal ischemic stroke. Arch Neurol. 2010;67:842-848.
4. Baccin CE, Krings T, Alvarez H, Ozanne A, Lasjaunias PL. A report of two cases with dolichosegmental intracranial arteries as a new feature of PHACES syndrome. Childs Nerv Syst. 2007;23:559-567.
5. Bhattacharya JJ, Luo CB, Alvarez H, Rodesch G, Pongpech S, Lasjaunias PL. PHACES syndrome: a review of eight previously unreported cases with late arterial occlusions. Neuroradiology. 2004;46:227-233.
6. Burrows PE, Robertson RL, Mulliken JB, Beardsley DS, Chaloupka JC, Ezekowitz RA, et al. Cerebral vasculopathy and neurologic sequelae in infants with cervicofacial hemangioma: report of eight patients. Radiology. 1998;207:601-607.
7. Drolet BA, Dohil M, Golomb MR, Wells R, Murowski L, Tamburro J, et al. Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association. Pediatrics. 2006;117:959-964.
8. Heyer GL, Dowling MM, Licht DJ, Tay SK, Morel K, Garzon MC, et al. The cerebral vasculopathy of PHACES syndrome. Stroke. 2008;39: 308-316.
9. Heyer GL, Millar WS, Ghatan S, Garzon MC. The neurologic aspects of PHACE: case report and review of the literature. Pediatr Neurol. 2006; 35:419-424.
10. James PA, McGaughran J. Complete overlap of PHACE syndrome and sternal malformation-vascular dysplasia association. Am J Med Genet. 2002;110:78-84.
11. Lin MC, Chen CH, Chi CS. PHACE syndrome: report of one case. Acta Paediatr Taiwan. 2003;44:379-382.
12. Pascual-Castroviejo I, Viano J, Pascual-Pascual SI, Quinones D. Congenital and evolving vascular disorders associated with cutaneous hemangiomas: case report. Neuropediatrics. 2009;40:148-151.
13. Prieto Espunes S, Santos-Juanes J, Medina Villanueva A, Concha Torre A, Rey Galan C, Sanchez Del Rio J. Death from cerebrovascular infarction in a patient with PHACES syndrome. J Am Acad Dermatol. 2004;51:142-143.
14. Haggstrom AN, Garzon MC, Baselga E, Chamlin SL, Frieden IJ, Holland K, et al. Risk for PHACE syndrome in infants with large facial hemangiomas. Pediatrics. 2010;126:e418-e426.
15. Hess CP, Fullerton HJ, Metry DW, Drolet BA, Siegel DH, Auguste KI, et al. Cervical and intracranial arterial anomalies in 70 patients with PHACE syndrome. AJNR Am J Neuroradiol. 2010;31:1980-1986.