Experimental approaches to the study of human primordial germ cells

Methods in Molecular Biology

Volumn 825, Issue , 2012, Pages 199-210

  Childs, Andrew J ^a   Anderson, Richard A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Gonad; Oocyte; Ovary; Primordial germ cell

Indexed keywords

ANIMAL EMBRYO; ARTICLE; CELL DIFFERENTIATION; CELL SEPARATION; CYTOLOGY; DISSECTION; FEMALE; FETUS; GERM CELL; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; ORGAN CULTURE TECHNIQUE; OVARY; PREGNANCY; PRIMARY CELL CULTURE; SEX DETERMINATION;

CELL DIFFERENTIATION; CELL SEPARATION; DISSECTION; EMBRYO, MAMMALIAN; FEMALE; FETUS; GERM CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; ORGAN CULTURE TECHNIQUES; OVARY; PREGNANCY; PRIMARY CELL CULTURE; SEX DETERMINATION ANALYSIS;

MAMMALIA; RODENTIA;

EID: 84863396923     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-436-0_15     Document Type: Article

References (27)

1. Matzuk MM, Lamb DJ (2008) The biology of infertility: research advances and clinical challenges. Nat Med 14:1197-1213.
2. Anderson RA, Fulton N, Cowan G, Coutts S, Saunders PT (2007) Conserved and divergent patterns of expression of DAZL, VASA and OCT4 in the germ cells of the human fatal ovary and testis. BMC Dev Biol 7:136.
3. Witschi E (1948) Migration of the germ cells of human embryos from the yolk sac to the primitive gonadal folds Contrib Embryol 32:67-80.
4. Hanley NA, Hagan DM, Clement-Jones M, Ball SG, Strachan T, Salas-Cortes L, McElreavey K, Lindsay S, Robson S, Bullen P, Ostrer H, Wilson DI (2000) SRY, SOX9, and DAX1 expression patterns during human sex determination and gonadal development. Mech Dev 91:403-407. (Pubitemid 30125948)
5. Wartenburg H (1981) Differentiation and development of the testes, in The Testis (Burger, H., de Kretser, D.M., Ed.), 2nd ed., Raven Press, New York.
6. Bendsen E, Byskov AG, Andersen CY, Westergaard LG (2006) Number of germ cells and somatic cells in human fatal ovaries during the first weeks after sex differentiation. Hum Reprod 21:30-35. (Pubitemid 41794289)
7. Gondos B, Westergaard L, Byskov AG (1986) Initiation of oogenesis in the human fatal ovary: ultrastructural and squash preparation study. Am J Obstet Gynecol 155:189-195. (Pubitemid 16100558)
8. Le Bouffant R, Guerquin MJ, Duquenne C, Frydman N, Coffigny H, Rouiller-Fabre V, Frydman R, Habert R, Livera G (2010) Meiosis initiation in the human ovary requires intrinsic retinoic acid synthesis. Hum Reprod 25:2579-2590.
9. Bullejos M, Koopman P (2004) Germ cells enter meiosis in a rostro-caudal wave during development of the mouse ovary. Mol Reprod Dev 68:422-428. (Pubitemid 39090411)
10. Menke DB, Koubova J, Page DC (2003) Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave. Dev Biol 262:303-312. (Pubitemid 37194509)
11. Anderson G, Gordon K (1996) Tissue processing, microtomy and paraffin sections, in Theory and Practice of Histological Techniques (Bankroft, J. D., and Stevens, A., Eds.) 4th ed., Churchill Livingstone, New York.
12. Fulton N, Martins da Silva SJ, Bayne RA, Anderson RA (2005) Germ cell proliferation and apoptosis in the developing human ovary. J Clin Endocrinol Metab 90:4664-4670. (Pubitemid 41166527)
13. Stoop H, Honecker F, Cools M, de Krijger R, Bokemeyer C, Looijenga LH (2005) Differentiation and development of human female germ cells during prenatal gonadogenesis: an immunohistochemical study. Hum Reprod 20:1466-1476. (Pubitemid 40852235)
14. De Felici M, Scaldaferri ML, Lobascio M, Iona S, Nazzicone V, Klinger FG, Farini D (2004) Experimental approaches to the study of primordial germ cell lineage and proliferation. Hum Reprod Update 10:197-206. (Pubitemid 38744866)
15. Donovan PJ (1994) Growth factor regulation of mouse primordial germ cell development. Curr Top Dev Biol 29:189-225. (Pubitemid 2155692)
16. Childs AJ, Kinnell,HL, Collins CS, Hogg K, Bayne RA, Green SJ, McNeilly AS, Anderson RA (2010) BMP signaling in the human fatal ovary is developmentally regulated and promotes primordial germ cell apoptosis. Stem Cells 28:1368-1378.
17. Childs AJ, Saunders PT, Anderson RA (2008) Modelling germ cell development in vitro. Mol Hum Reprod 14:501-511.
18. Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ, Blumenthal PD Huggins GR, Gearhart JD (1998) Derivation of pluripotent stem cells from cultured human primordial germ cell., Proc Natl Acad Sci USA 95:13726-13731. (Pubitemid 28523040)
19. Turnpenny L, Brickwood S, Spalluto CM, Piper K, Cameron IT, Wilson DI, Hanley NA (2003) Derivation of human embryonic germ cells: an alternative source of pluripotent stem cells. Stem Cells 21:598-609. (Pubitemid 37444116)
20. Lambrot R, Coffigny H, Pairault C, Donnadieu AC, Frydman R, Habert R, Rouiller-Fabre V (2006) Use of organ culture to study the human fatal testis development: effect of retinoic acid. J Clin Endocrinol Metab 91:2696-2703. (Pubitemid 44024640)
21. Hoei-Hansen CE, Nielsen JE, Almstrup K, Sonne SB, Graem N, Skakkebaek NE, Leffers H, Rajpert-De Meyts E (2004) Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors. Clin Cancer Res 10:8521-8530. (Pubitemid 40053419)
22. Pauls K, Jager R, Weber S, Wardelmann E, Koch A, Buttner R, Schorle H (2005) Transcription factor AP-2gamma, a novel marker of gonocytes and seminomatous germ cell tumors. Int J Cancer 115:470-477. (Pubitemid 40663753)
23. Bayne RA, Eddie SL, Collins CS, Childs AJ, Jabbour HN, Anderson RA (2009) Prostaglandin E2 as a regulator of germ cells during ovarian development. J Clin Endocrinol Metab 94:4053-4060.
24. Childs AJ, Bayne RA, Murray AA, Martins Da Silva SJ, Collins CS, Spears N, Anderson RA (2010) Differential expression and regulation by activin of the neurotrophins BDNF and NT4 during human and mouse ovarian development. Dev Dyn 239:1211-1219.
25. Farhi J, Fisch B, Garor R, Peled Y, Pinkas H, Abir R (2010) Neurotrophin 4 enhances in vitro follicular assembly in human fatal ovaries, Fertil Steril. doi: doi: 10.1016/j. fertnstert.2010.03.051 .
26. Friel A, Houghton JA, Glennon M, Lavery R, Smith T, Nolan A, Maher M (2002) A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men. Int J Androl 25:59-64. (Pubitemid 34146676)
27. McClellan KA, Gosden R, Taketo T (2003) Continuous loss of oocytes throughout meiotic prophase in the normal mouse ovary. Dev Biol 258:334-348. (Pubitemid 36686722)