New substrates and enzyme assays for the detection of mucopolysaccharidosis III (Sanfilippo Syndrome) types a, b, c, and d by tandem mass spectrometry

Bioconjugate Chemistry

Volumn 23, Issue 3, 2012, Pages 557-564

  Wolfe, Brian J ^a   Ghomashchi, Farideh ^a   Kim, Tim ^a   Abam, Cynthia A ^a   Sadilek, Martin ^a   Jack, Rhona ^b   Thompson, Jerry N ^c   Scott, C Ronald ^d   Gelb, Michael H ^a   Turecek, Frantisek ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SEATTLE CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; CELL CULTURE; ENZYMES; FIBROBLASTS; MASS SPECTROMETRY; SULFUR COMPOUNDS;

EFFICIENT SYNTHESIS; ENZYMATIC ASSAY; ENZYME ASSAYS; ENZYME DEFICIENCIES; HEPARAN SULPHATE; INTERNAL STANDARDS; LYSATES; SULFATASES; TANDEM MASS SPECTROMETRY; TANDEM-MASS SPECTROMETRY;

CHEMICAL MODIFICATION;

ALPHA N ACETYLGLUCOSAMINIDASE; N ACETYLGLUCOSAMINE 6 SULFATASE; REAGENT; UMBELLIFERONE DERIVATIVE;

ARTICLE; CELL LYSATE; CHEMICAL STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE; FIBROBLAST; HUMAN; HUMAN CELL; REACTION ANALYSIS; SANFILIPPO SYNDROME; STRUCTURE ANALYSIS; SYNTHESIS; TANDEM MASS SPECTROMETRY;

EID: 84863371787     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc200609x     Document Type: Article

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