FERM domain containing protein 7 (FRMD7) upregulates the expression of neuronal cytoskeletal proteins and promotes neurite outgrowth in Neuro-2a cells

Molecular Vision

Volumn 18, Issue , 2012, Pages 1428-1435

  Pu, Jiali ^a   Lu, Xiaoxiong ^a   Zhao, Guohua ^a   Yan, Yaping ^a   Tian, Jun ^a   Zhang, Baorong ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSKELETON PROTEIN; FERM DOMAIN CONTAINING PROTEIN 7; MICROTUBULE ASSOCIATED PROTEIN 2; NESTIN; NEUROFILAMENT H PROTEIN; NEUROFILAMENT L PROTEIN; NEUROFILAMENT M PROTEIN; NEUROMODULIN; NEURON SPECIFIC CLASS III BETA TUBULIN; REGULATOR PROTEIN; RETINOIC ACID; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL STRUCTURE; CONTROLLED STUDY; FRMD7 GENE; GAP 43 GENE; GENE; GENE OVEREXPRESSION; MAPT GENE; MOUSE; MTAP2 GENE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; NF H GENE; NF L GENE; NF M GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUJ 1 GENE; UPREGULATION;

ACTINS; ANIMALS; CELL COUNT; CELL DIFFERENTIATION; CELL LINE, TUMOR; CYTOSKELETAL PROTEINS; GAP-43 PROTEIN; GENE EXPRESSION REGULATION; INTERMEDIATE FILAMENT PROTEINS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; NERVE TISSUE PROTEINS; NEURITES; NEUROBLASTOMA; NEUROFILAMENT PROTEINS; PLASMIDS; PROTEIN TRANSPORT; RNA, MESSENGER; TAU PROTEINS; TRANSFECTION; TRETINOIN; TUBULIN;

EID: 84863333389     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Lee AG, Brazis PW. Localizing forms of nystagmus: symptoms, diagnosis, and treatment. Curr Neurol Neurosci Rep 2006; 6:414-20. [PMID: 16928352]
2. Sarvananthan N, Surendran M, Roberts EO, Jain S, Thomas S, Shah N, Proudlock FA, Thompson JR, McLean RJ, Degg C, Woodruff G, Gottlob I. The prevalence of nystagmus: the Leicestershire nystagmus survey. Invest Ophthalmol Vis Sci 2009; 50:5201-6. [PMID: 19458336]
3. McLean R, Proudlock F, Thomas S, Degg C, Gottlob I. Congenital nystagmus: randomized, controlled, doublemasked trial of memantine/gabapentin. Ann Neurol 2007; 61:130-8. [PMID: 17279539]
4. Tarpey P, Thomas S, Sarvananthan N, Mallya U, Lisgo S, Talbot CJ, Roberts EO, Awan M, Surendran M, McLean RJ, Reinecke RD, Langmann A, Lindner S, Koch M, Jain S, Woodruff G, Gale RP, Degg C, Droutsas K, Asproudis I, Zubcov AA, Pieh C, Veal CD, Machado RD, Backhouse OC, Baumber L, Constantinescu CS, Brodsky MC, Hunter DG, Hertle RW, Read RJ, Edkins S, O'Meara S, Parker A, Stevens C, Teague J, Wooster R, Futreal PA, Trembath RC, Stratton MR, Raymond FL, Gottlob I. Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus. Nat Genet 2006; 38:1242-4. [PMID: 17013395]
5. He X, Gu F, Wang Y, Yan J, Zhang M, Huang S, Ma X. A novel mutation in FRMD7 causing X-linked idiopathic congenital nystagmus in a large family. Mol Vis 2008; 14:56-60. [PMID: 18246032]
6. Li N, Wang L, Cui L, Zhang L, Dai S, Li H, Chen X, Zhu L, Hejtmancik JF, Zhao K. Five novel mutations of the FRMD7 gene in Chinese families with X-linked infantile nystagmus. Mol Vis 2008; 14:733-8. [PMID: 18431453]a
7. Schorderet DF, Tiab L, Gaillard MC, Lorenz B, Klainguti G, Kerrison JB, Traboulsi EI, Munier FL. Novel mutations in FRMD7 in X-linked congenital nystagmus. Hum Mutat 2007; 28:525. [PMID: 17397053]
8. Zhang B, Liu Z, Zhao G, Xie X, Yin X, Hu Z, Xu S, Li Q, Song F, Tian J, Luo W, Ding M, Yin J, Xia K, Xia J. Novel mutations of the FRMD7 gene in X-linked congenital motor nystagmus. Mol Vis 2007; 13:1674-9. [PMID: 17893669]a
9. Zhang Q, Xiao X, Li S, Guo X. FRMD7 mutations in Chinese families with X-linked congenital motor nystagmus. Mol Vis 2007; 13:1375-8. [PMID: 17768376]b
10. Betts-Henderson J, Bartesaghi S, Crosier M, Lindsay S, Chen HL, Salomoni P, Gottlob I, Nicotera P. The nystagmusassociated FRMD7 gene regulates neuronal outgrowth and development. Hum Mol Genet 2010; 19:342-51. [PMID: 19892780]
11. Pu J, Li Y, Liu Z, Yan Y, Tian J, Chen S, Zhang B. Expression and localization of FRMD7 in human fetal brain, and a role for F-actin. Mol Vis 2011; 17:591-7. [PMID: 21386928]
12. Luo L. Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity. Annu Rev Cell Dev Biol 2002; 18:601-35. [PMID: 12142283]
13. Shea TB, Fischer I, Sapirstein VS. Effect of retinoic acid on growth and morphological differentiation of mouse NB2a neuroblastoma cells in culture. Brain Res 1985; 353:307-14. [PMID: 2994850]
14. Wu G, Fang Y, Lu ZH, Ledeen RW. Induction of axon-like and dendrite-like processes in neuroblastoma cells. J Neurocytol 1998; 27:1-14. [PMID: 9530995]
15. Tegenge MA, Roloff F, Bicker G. Rapid Differentiation of Human Embryonal Carcinoma Stem Cells (NT2) into Neurons for Neurite Outgrowth Analysis. Cell Mol Neurobiol 2011; 31:635-43. [PMID: 21331625]
16. Livak KJ, Schmittgen TD. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2-CT Method. Methods 2001; 25:402-8. [PMID: 11846609]
17. Matus A. Microtubule-associated proteins and neuronal morphogenesis. J Cell Sci Suppl 1991; 15:61-7. [PMID: 1824108]
18. Carden MJ, Trojanowski JQ, Schlaepfer WW, Lee VM. Twostage expression of neurofilament polypeptides during rat neurogenesis with early establishment of adult phosphorylation patterns. J Neurosci 1987; 7:3489-504. [PMID: 3119790]
19. Kim H, Binder LI, Rosenbaum JL. The periodic association of MAP2 with brain microtubules in vitro. J Cell Biol 1979; 80:266-76. [PMID: 457745]
20. Selden SC, Pollard TD. Interaction of actin filaments with microtubules is mediated by microtubule-associated proteins and regulated by phosphorylation. Ann N Y Acad Sci 1986; 466:803-12. [PMID: 3460455]
21. Sattilaro RF. Interaction of microtubule-associated protein 2 with actin filaments. Biochemistry 1986; 25:2003-9. [PMID: 3707926]
22. Cáceres A, Banker GA, Binder L. Immunocytochemical localization of tubulin and microtubule-associated protein 2 during the development of hippocampal neurons in culture. J Neurosci 1986; 6:714-22. [PMID: 3514816]
23. Yamada KM, Spooner BS, Wessells NK. Axon growth: roles of microfilaments and microtubules. Proc Natl Acad Sci USA 1970; 66:1206-12. [PMID: 5273449]
24. Lees JF, Shneidman PS, Skuntz SF, Carden MJ, Lazzarini RA. The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. EMBO J 1988; 7:1947-55. [PMID: 3138108]
25. Myers MW, Lazzarini RA, Lee VM, Schlaepfer WW, Nelson DL. The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. EMBO J 1987; 6:1617-26. [PMID: 3608989]
26. Perrot R, Berges R, Bocquet A, Eyer J. Review of the multiple aspects of neurofilament functions and their possible contribution to neurodegeneration. Mol Neurobiol 2008; 38:27-65. [PMID: 18649148]
27. Walker KL, Yoo HK, Undamatla J, Szaro BG. Loss of neurofilaments alters axonal growth dynamics. J Neurosci 2001; 21:9655-66. [PMID: 11739575]
28. Julien JP, Meyer D, Flavell D, Hurst J, Grosveld F. Cloning and developmental expression of the murine neurofilament gene family. Brain Res 1986; 387:243-50. [PMID: 3103856]
29. Breen KC, Anderton BH. Temporal expression of neurofilament polypeptides in differentiating neuroblastoma cells. Neuroreport 1991; 2:21-4. [PMID: 1662992]