Binding of phytopolyphenol piceatannol disrupts β/γ subunit interactions and rate-limiting step of steady-state rotational catalysis in Escherichia coli F1-ATpase

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 22771-22780

  Sekiya, Mizuki ^a   Nakamoto, Robert K ^b   Nakanishi Matsui, Mayumi ^a   Futai, Masamitsu ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP SYNTHASE; CARBOXYL-TERMINAL; CATALYTIC CYCLES; CATALYTIC RATES; DURATION TIME; RATE LIMITING; RATE-LIMITING STEPS; ROTATIONAL CATALYSIS; ROTOR-STATOR INTERACTIONS; SINGLE MOLECULE; TEMPERATURE DEPENDENCE;

ACTIVATION ENERGY; ARRHENIUS PLOTS; ESCHERICHIA COLI; ROTORS (WINDINGS); STATORS;

ROTATION;

LYSINE; METHIONINE; PICEATANNOL; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; QUERCETIN; RESVERATROL;

AMINO ACID SUBSTITUTION; ARTICLE; BETA CHAIN; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; DRUG PROTEIN BINDING; ESCHERICHIA COLI; GAMMA CHAIN; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; ROTATIONAL CATALYSIS; STEADY STATE; TEMPERATURE DEPENDENCE;

AMINO ACID SEQUENCE; ANTIOXIDANTS; BINDING SITES; CATALYSIS; ENZYME ACTIVATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POLYPHENOLS; PROTEIN SUBUNITS; PROTON-TRANSLOCATING ATPASES; QUERCETIN; STILBENES; TEMPERATURE; THERMODYNAMICS;

ESCHERICHIA COLI;

EID: 84863331366     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.374868     Document Type: Article

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