Variations in the occurrence of specific rpoB mutations in rifampicinresistant Mycobacterium tuberculosis isolates from patients of different ethnic groups in Kuwait

Indian Journal of Medical Research

Volumn 135, Issue 5, 2012, Pages 756-762

  Ahmad, Suhail ^a   Al Mutairi, Noura M ^a   Mokaddas, Eiman ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Ethnic differences; Mycobacterium tuberculosis; Rifampicin resistance; rpoB mutations

Indexed keywords

ETHAMBUTOL; ISONIAZID; RIFAMPICIN; STREPTOMYCIN;

AMINO ACID SEQUENCE; ARTICLE; BACTERIUM ISOLATE; CONTROLLED STUDY; DNA EXTRACTION; DNA FINGERPRINTING; DNA POLYMORPHISM; DNA SEQUENCE; DRUG SENSITIVITY; ETHNIC GROUP; FEMALE; GENE; GENE MUTATION; GYRA GENE; HUMAN; KATG GENE; KUWAIT; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; MYCOBACTERIUM TUBERCULOSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RPOB GENE; TUBERCULOSIS;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; ETHNIC GROUPS; HUMANS; KUWAIT; MUTATION; MYCOBACTERIUM TUBERCULOSIS; RIFAMPIN; SEQUENCE ANALYSIS, DNA; TUBERCULOSIS, MULTIDRUG-RESISTANT;

EID: 84863328877     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. World Health Organization. Global tuberculosis control: epidemiology, strategy and financing. WHO report 2009. WHO/HTM/TB/2009.411. Geneva, Switzerland: WHO; 2009.
2. Wright A, Zignol M, Van Deun A, Falzon D, Gerdes SR, Feldman K, et al. for the Global Project on Anti-Tuberculosis Drug Resistance Surveillance. Epidemiology of antituberculosis drug resistance 2002-07: an updated analysis of the Global Project on Anti-Tuberculosis Drug Resistance Surveillance. Lancet 2009; 373: 1861-73.
3. Ahmad S, Mokaddas E. Recent advances in the diagnosis and treatment of multidrug-resistant tuberculosis. Respir Med 2009; 103: 1777-90.
4. World Health Organization. Multidrug and extensively drugresistant TB (M/XDR-TB): 2010 global report on surveillance and response. WHO/HTM/TB/2010.3, Geneva, Switzerland: WHO; 2010.
5. Sandman L, Schluger NW, Davidow AL, Bonk S. Risk factors for rifampin-monoresistant tuberculosis: a case-control study. Am J Respir Crit Care Med 1999; 159: 468-72.
6. Mokaddas E, Ahmad S, Abal AT, Al-Shami AS. Molecular fingerprinting reveals familial transmission of rifampinresistant tuberculosis in Kuwait. Ann Saudi Med 2005; 25: 150-3.
7. Telenti A, Imboden P, Marchesi F, Lowrie D, Cole S, Colston MJ, et al. Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis. Lancet 1993; 341: 647-50.
8. Palomino JC, Martin A, Von Groll A, Portaels F. Rapid culturebased methods for drug-resistance detection in Mycobacterium tuberculosis. J Microbiol Methods 2008; 75: 161-6.
9. Jou R, Chen HY, Chiang CY, Yu MC, Su IJ. Genetic diversity of multidrug-resistant Mycobacterium tuberculosis isolates and identification of 11 novel rpoB alleles in Taiwan. J Clin Microbiol 2005; 43: 1390-4.
10. Heep M, Brandstatter B, Rieger U, Lehn N, Richter E, Rüsch-Gerdes S, et al. Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates. J Clin Microbiol 2001; 39: 107-10.
11. Hirano K, Abe C, Takahashi M. Mutations in the rpoB gene of rifampin-resistant Mycobacterium tuberculosis strains isolated mostly in Asian countries and their rapid detection by line probe assay. J Clin Microbiol 1999; 37: 2663-6.
12. Sintchenko V, Chew WK, Jelfs PJ, Gilbert GL. Mutations in rpoB gene and rifabutin susceptibility of multidrug-resistant Mycobacterium tuberculosis strains isolated in Australia. Pathology 1999; 31: 257-60.
13. Ahmad S, Mokaddas E, Fares E. Characterization of rpoB mutations in rifampin-resistant clinical Mycobacterium tuberculosis isolates from Kuwait and Dubai. Diagn Microbiol Infect Dis 2002; 44: 245-52.
14. Marttila HJ, Soini H, Eerola E, Vyshnevskaya E, Vyshnevskiy BI, Otten TF, et al. A Ser315Thr substitution in KatG is predominant in genetically heterogeneous multidrug-resistant Mycobacterium tuberculosis isolates originating from the St. Petersburg area in Russia. Antimicrob Agents Chemother 1998; 42: 2443-5.
15. Ahmad S, Fares E, Araj GF, Chugh TD, Mustafa AS. Prevalence of S315T mutation within the katG gene in isoniazid-resistant clinical Mycobacterium tuberculosis isolates from Dubai and Beirut. Int J Tuberc Lung Dis 2002; 6: 920-6.
16. Mokrousov I, Narvskaya O, Otten T, Limeschenko E, Steklova L, Vyshnevskiy B. High prevalence of KatG Ser315Thr substitution among isoniazid-resistant Mycobacterium tuberculosis clinical isolates from northwestern Russia, 1996-2001. Antimicrob Agents Chemother 2002; 46: 1417-24.
17. Ahmad S, Mokaddas E. Contribution of AGC to ACC and other mutations at codon 315 of the katG gene in isoniazidresistant Mycobacterium tuberculosis isolates from the Middle East. Int J Antimicrob Agents 2004; 23: 473-9.
18. Ahmad S, Itani LY, Fares E, Araj GF. Varying prevalence of embB codon 306 mutations in ethambutol-resistant clinical Mycobacterium tuberculosis isolates from Beirut and Dubai. J Chemother 2008; 20: 285-7.
19. Abal AT, Ahmad S, Mokaddas E. Variations in the occurrence of the S315T mutation within the katG gene in isoniazidresistant clinical Mycobacterium tuberculosis isolates from Kuwait. Microb Drug Resist 2002; 8: 99-105.
20. Mokaddas E, Ahmad S, Samir I. Secular trends in susceptibility patterns of Mycobacterium tuberculosis isolates in Kuwait, 1996-2005. Int J Tuberc Lung Dis 2008; 12: 319-25.
21. Mokaddas E, Ahmad S. Development and evaluation of a multiplex PCR for rapid detection and differentiation of Mycobacterium tuberculosis complex members from nontuberculous mycobacteria. Jpn J Infect Dis 2007; 60: 140-4.
22. Al-Mutairi NM, Ahmad S, Mokaddas E. Performance comparison of four methods for rapid detecting of multidrugresistant Mycobacterium tuberculosis strains. Int J Tuberc Lung Dis 2011; 15: 110-5.
23. Ahmad S, Mokaddas E, Jaber, AA. Rapid detection of ethambutol-resistant Mycobacterium tuberculosis strains by PCR-RFLP targeting embB codons 306 and 497 and iniA codon 501 mutations. Mol Cell Probes 2004; 18: 299-306.
24. Ahmad S Mokaddas E. The occurrence of rare rpoB mutations in rifampicin-resistant clinical Mycobacterium tuberculosis isolates from Kuwait. Int J Antimicrob Agents 2005; 26: 205-12.
25. Sreevatsan S, Pan X, Stockbauer KE, Connell ND, Kreiswirth BN, Whittam TS, et al. Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination. Proc Natl Acad Sci USA 1997; 94: 9869-74.
26. Ahmad S, Jaber AA, Mokaddas E. Frequency of embB codon 306 mutations in ethambutol-susceptible and-resistant clinical Mycobacterium tuberculosis isolates in Kuwait. Tuberculosis (Edinb) 2007; 87: 123-9.
27. Hwang HY, Chang CY, Chang LL, Chang SF, Chang YH, Chen YJ. Characterization of rifampin-resistant Mycobacterium tuberculosis in Taiwan. J Med Microbiol 2003; 52: 239-45.
28. Huang H, Jin Q, Chen X, Zhuang Y. Characterization of rpoB mutations in rifampin-resistant Mycobacterium tuberculosis isolates in China. Tuberculosis (Edinb) 2002; 82: 79-83.
29. Nikolayevsky V, Brown T, Balabanova Y, Ruddy M, Fedorin I, Drobniewski F. Detection of mutations associated with isoniazid and rifampin resistance in Mycobacterium tuberculosis isolates from Samara region, Russian Federation. J Clin Microbiol 2004; 42: 4498-502.
30. Ahmad S. New approaches in the diagnosis and treatment of latent tuberculosis infection. Respir Res 2010; 11: 169.