Hull down on the horizon: A randomized trial of unruptured brain arteriovenous malformations (ARUBA) trial

Stroke

Volumn 43, Issue 7, 2012, Pages 1744-1745

  Mohr, J P ^a   Moskowitz, Alan J ^b   Parides, Michael ^b   Stapf, Christian ^c   Young, William L ^d  

^a NEUROLOGICAL INSTITUTE   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

^c HÔPITAL LARIBOISIÈRE   (France)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

arteriovenous malformations; AVM; clinical trials; treatment

Indexed keywords

ARTIFICIAL EMBOLISM; BRAIN ARTERIOVENOUS MALFORMATION; BRAIN HEMORRHAGE; CEREBROVASCULAR SURGERY; EDITORIAL; HUMAN; MORTALITY; PRIORITY JOURNAL; QUALITY OF LIFE; RADIOSURGERY; RANDOMIZED CONTROLLED TRIAL (TOPIC); TREATMENT OUTCOME;

ARTERIOVENOUS FISTULA; HUMANS; INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; MULTICENTER STUDIES AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84863319308     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.112.653584     Document Type: Editorial

References (17)

1. Cockroft KM. Perfect storm. Stroke. 2012;43:1979-1981.
2. Mohr JP, Moskowitz AJ, Stapf C, Hartmann A, Lord K, Marshall SM, et al. The ARUBA trial: current status, future hopes. Stroke. 2010;41: e537-e540.
3. Ross J, Al-Shahi Salman R. Interventions for treating brain arteriovenous malformations in adults. Cochrane Database Syst Rev. 2010;7: CD003436.
4. Choi JH, Mast H, Sciacca RR, Hartmann A, Khaw AV, Mohr JP, et al. Clinical outcome after first and recurrent hemorrhage in patients with untreated brain arteriovenous malformation. Stroke. 2006;37:1243-1247. (Pubitemid 43731870)
5. Ogilvy CS, Stieg PE, Awad I, Brown RD Jr, Kondziolka D, Rosenwasser R, et al. AHA scientific statement: recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association. Stroke. 2001;32:1458-1471. (Pubitemid 32530442)
6. Barnett HJ, Peerless SJ, McCormick CW. In answer to the question: 'as compared to what?' A progress report on the EC/IC bypass study. Stroke. 1980;11:137-140.
7. Wedderburn CJ, van Beijnum J, Bhattacharya JJ, Counsell CE, Papanastassiou V, Ritchie V, et al. Outcome after interventional or conservative management of unruptured brain arteriovenous malformations: a prospective, population-based cohort study. Lancet Neurol. 2008;7:223-230.
8. Marshall RS, Zarahn E, Alon L, Minzer B, Lazar RM, Krakauer JW. Early imaging correlates of subsequent motor recovery after stroke. Ann Neurol. 2009;65:596-602.
9. Cockroft KM. Unruptured brain arteriovenous malformations should be treated conservatively: no. Stroke. 2007;38:3310-3311.
10. Stapf C, Mast H, Sciacca RR, Choi JH, Khaw AV, Connolly ES, et al. Predictors of hemorrhage in patients with untreated brain arteriovenous malformation. Neurology. 2006;66:1350-1355. (Pubitemid 43739643)
11. Kim H, McCulloch CE, Johnston SC, Lawton MT, Sidney S, Young WL. Comparison of 2 approaches for determining the natural history risk of brain arteriovenous malformation rupture. Am J Epidemiol. 2010;171:1317-1322.
12. Ondra SL, Troupp H, George ED, Schwab K. The natural history of symptomatic arteriovenous malformations of the brain: a 24-year follow-up assessment. J Neurosurg. 1990;73:387-391. (Pubitemid 20260008)
13. Hernesniemi JA, Dashti R, Juvela S, Vaart K, Niemela M, Laakso A. Natural history of brain arteriovenous malformations: a long-term follow-up study of risk of hemorrhage in 238 patients. Neurosurgery. 2008;63:823-829; discussion 829-831.
14. Dupuis-Girod S, Ginon I, Saurin JC, Marion D, Guillot E, Decullier E, et al. Bevacizumab in patients with hereditary hemorrhagic telangiectasia and severe hepatic vascular malformations and high cardiac output. JAMA. 2012;307:948-955.
15. Concato J, Shah N, Horwitz RI. Randomized, controlled trials, observational studies, and the hierarchy of research designs. N Engl J Med. 2000;342:1887-1892. (Pubitemid 30419054)
16. Berman MF, Hartmann A, Mast H, Sciacca RR, Mohr JP, Pile-Spellman J, et al. Determinants of resource utilization in the treatment of brain arteriovenous malformations. AJNR Am J Neuroradiol. 1999;20: 2004-2008.
17. Fiehler J, Stapf C. ARUBA-beating natural history in unruptured brain AVMs by intervention. Neuroradiology. 2008;50:465-467.