Extracapsular spread and adjuvant therapy in human papillomavirus-related, p16-positive oropharyngeal carcinoma

Cancer

Volumn 118, Issue 14, 2012, Pages 3519-3530

  Sinha, Parul ^a   Lewis Jr , James S ^a   Piccirillo, Jay F ^a   Kallogjeri, Dorina ^a   Haughey, Bruce H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

adjuvant therapy; extracapsular spread, oropharyngeal cancer; human papillomavirus; lymphatic metastasis; p16 protein

Indexed keywords

CETUXIMAB; CISPLATIN; PROTEIN P16;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CHEMORADIOTHERAPY; CONTROLLED STUDY; DISEASE FREE SURVIVAL; EXTRACAPSULAR SPREAD; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; METASTASIS; MULTIPLE CYCLE TREATMENT; MULTIVARIATE ANALYSIS; OROPHARYNX CARCINOMA; OROPHARYNX SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROTEIN EXPRESSION; SOFT TISSUE METASTASIS; WART VIRUS;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; OROPHARYNGEAL NEOPLASMS; PAPILLOMAVIRIDAE; PROGNOSIS;

EID: 84863307023     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.26671     Document Type: Article

References (35)

1. Cooper JS, Pajak TF, Forastiere A, et al. Precisely defining high-risk operable head and neck tumors based on RTOG 85-03 and 88-24: targets for postoperative radiochemotherapy? Head Neck. 1998; 20: 588-594. (Pubitemid 28405799)
2. Johnson JT, Wagner RL, Myers EN,. A long term assessment of adjuvant chemotherapy on outcome of patients with extracapsular spread of cervical metastases from squamous carcinoma of the head and neck. Cancer. 1996; 77: 181-185. (Pubitemid 26002755)
3. Cooper JS, Pajak TF, Forastiere A, et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med. 2004; 350: 1937-1944.
4. Bernier J, Domenge C, Ozsahin M, et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck. N Engl J Med. 2004; 350: 1945-1952. (Pubitemid 38580197)
5. Sturgis EM, Cinciripini PM,. Trends in head and neck cancer incidence in relation to smoking prevalence: an emerging epidemic of human papillomavirus-associated cancers. Cancer. 2007; 110: 1429-1435. (Pubitemid 47463055)
6. Jemal A, Siegel R, Xu J, Ward E,. Cancer statistics, 2010. CA Cancer J Clin. 2010; 60: 277-300.
7. Mellin H, Friesland S, Lewensohn R, et al. Human papillomavirus (HPV) DNA in tonsillar cancer: clinical correlates, risk of relapse, and survival. Int J Cancer. 2000; 89: 300-304. (Pubitemid 30430748)
8. Mellin DH, Lindquist D, Bjornestal L, et al. p16(INK4a) correlates to human papillomavirus presence, response to radiotherapy and clinical outcome in tonsillar carcinoma. Anticancer Res. 2005; 25: 4375-4383. (Pubitemid 41729481)
9. Licitra L, Perrone F, Bossi P, et al. High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma. J Clin Oncol. 2006; 24: 5630-5636. (Pubitemid 46631302)
10. Fischer CA, Zlobec I, Green E, et al. Is the improved prognosis of p16 positive oropharyngeal squamous cell carcinoma dependent of the treatment modality? Int J Cancer. 2010; 126: 1256-1262.
11. Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010; 363: 24-35.
12. Steiner W, Fierek O, Ambrosch P, Hommerich CP, Kron M,. Transoral laser microsurgery for squamous cell carcinoma of the base of the tongue. Arch Otolaryngol Head Neck Surg. 2003; 129: 36-43. (Pubitemid 36070874)
13. Rich JT, Milov S, Lewis JS Jr, Thorstad WL, Adkins D, Haughey BH,. Transoral laser microsurgery (TLM) ± adjuvant therapy for advanced stage oropharyngeal cancer: outcomes and prognostic factors. Laryngoscope. 2009; 119: 1709-1719.
14. Haughey BH, Hinni ML, Salassa JR, et al. Transoral laser microsurgery as primary treatment for advanced-stage oropharyngeal cancer: a United States multicenter study [published online ahead of print January 31, 2011]. Head Neck. 2011.
15. Bennett SH, Futrell JW, Roth JA, Hoye RC, Ketcham AS,. Prognostic significance of histologic host response in cancer of the larynx or hypopharynx. Cancer. 1971; 28: 1255-1265.
16. Snow GB, Annyas AA, VanSlooten AE,. AAM: prognostic factors of neck node metastasis. Clin Otolaryngol. 1982; 7: 185-189.
17. Johnson JT, Myers EN, Bedetti CD, Barnes EL, Schramm VL Jr, Thearle PB,. Cervical lymph node metastases. Incidence and implications of extracapsular carcinoma. Arch Otolaryngol. 1985; 111: 534-537. (Pubitemid 15249730)
18. Ferlito A, Robbins KT, Shaha AR, et al. Current considerations in neck dissection. Acta Otolaryngol. 2002; 122: 323-329. (Pubitemid 34538936)
19. de Carvalho MB,. Quantitative analysis of the extent of extracapsular invasion and its prognostic significance: a prospective study of 170 cases of carcinoma of the larynx and hypopharynx. Head Neck. 1998; 20: 16-21. (Pubitemid 27528297)
20. Klozar J, Kratochvil V, Salakova M, et al. HPV status and regional metastasis in the prognosis of oral and oropharyngeal cancer. Eur Arch Otorhinolaryngol. 2008; 265 (suppl 1): S75-S82.
21. Wenzel S, Sagowski C, Kehrl W, Metternich FU,. The prognostic impact of metastatic pattern of lymph nodes in patients with oral and oropharyngeal squamous cell carcinomas. Eur Arch Otorhinolaryngol. 2004; 261: 270-275. (Pubitemid 38680325)
22. Shimizu K, Inoue H, Saitoh M, et al. Distribution and impact of lymph node metastases in oropharyngeal cancer. Acta Otolaryngol. 2006; 126: 872-877. (Pubitemid 44091771)
23. Lewis JS Jr, Carpenter DH, Thorstad WL, Zhang Q, Haughey BH,. Extracapsular extension is a poor predictor of disease recurrence in surgically treated oropharyngeal squamous cell carcinoma [published online ahead of print June 24, 2011]. Mod Pathol. 2011.
24. Piccirillo JF, Tierney RM, Costas I, Grove L, Spitznagel EL Jr,. Prognostic importance of comorbidity in a hospital-based cancer registry. JAMA. 2004; 291: 2441-2447. (Pubitemid 38669187)
25. Hyland A, Li Q, Bauer JE, Giovino GA, Steger C, Cummings KM,. Predictors of cessation in a cohort of current and former smokers followed over 13 years. Nicotine Tob Res. 2004; 6 (suppl 3): S363-S369. (Pubitemid 40124775)
26. D'souza G, Kreimer AR, Viscidi R, et al. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med. 2007; 356: 1944-1956. (Pubitemid 46740304)
27. Carter RL,. The pathologist's appraisal of neck dissections. Eur Arch Otorhinolaryngol. 1993; 250: 429-431. (Pubitemid 24003331)
28. Jose J, Moor JW, Coatesworth AP, Johnston C, MacLennan K,. Soft tissue deposits in neck dissections of patients with head and neck squamous cell carcinoma: prospective analysis of prevalence, survival, and its implications. Arch Otolaryngol Head Neck Surg. 2004; 130: 157-160. (Pubitemid 38182539)
29. Mamelle G, Pampurik J, Luboinski B, Lancar R, Lusinchi A, Bosq J,. Lymph node prognostic factors in head and neck squamous cell carcinomas. Am J Surg. 1994; 168: 494-498. (Pubitemid 24345707)
30. Pinsolle J, Pinsolle V, Majoufre C, Duroux S, Demeaux H, Siberchicot F,. Prognostic value of histologic findings in neck dissections for squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 1997; 123: 145-148. (Pubitemid 27076508)
31. Pignon JP, le Maitre A, Maillard E, Bourhis J,; MACH-NC Collaborative Group. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiother Oncol. 2009; 92: 4-14.
32. Myers EN, Alvi A,. Management of carcinoma of the supraglottic larynx: evolution, current concepts, and future trends. Laryngoscope. 1996; 106: 559-567. (Pubitemid 26137833)
33. Vaidya AM, Petruzzelli GJ, Clark J, Emami B,. Patterns of spread in recurrent head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg. 2001; 125: 393-396. (Pubitemid 33661067)
34. Greven KM, White DR, Browne JD, Williams DW 3rd, McGuirt WF Sr, D'Agostino RB Jr,. Swallowing dysfunction is a common sequelae after chemoradiation for oropharynx carcinoma. Am J Clin Oncol. 2008; 31: 209-212.
35. Machtay M, Moughan J, Trotti A, et al. Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis. J Clin Oncol. 2008; 26: 3582-3589.