메뉴 건너뛰기




Volumn 287, Issue 27, 2012, Pages 22521-22532

Site-specific phosphorylation protects glycogen synthase kinase-3β from calpain-mediated truncation of its N and C termini

Author keywords

[No Author keywords available]

Indexed keywords

AUTOINHIBITORY DOMAIN; C TERMINUS; CALPAINS; CEREBELLAR GRANULE NEURONS; CLEAVAGE SITES; DEPHOSPHORYLATIONS; GLYCOGEN SYNTHASE KINASE-3; KEY REGULATORS; KINASE DOMAINS; N-TERMINALS; NEURONAL APOPTOSIS; SITE-SPECIFIC; TRUNCATED PRODUCT;

EID: 84863305898     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.321349     Document Type: Article
Times cited : (23)

References (42)
  • 1
    • 0035665719 scopus 로고    scopus 로고
    • The structure of phosphorylated GSK-3β complexed with a peptide, FRATtide, that inhibits β-catenin phosphorylation
    • DOI 10.1016/S0969-2126(01)00679-7, PII S0969212601006797
    • Bax, B., Carter, P. S., Lewis, C., Guy, A. R., Bridges, A., Tanner, R., Pettman, G., Mannix, C., Culbert, A. A., Brown, M. J., Smith, D. G., and Reith, A. D. (2001) The structure of phosphorylated GSK-3β complexed with a peptide, FRATtide, that inhibits β-catenin phosphorylation. Structure 9, 1143-1152 (Pubitemid 34025049)
    • (2001) Structure , vol.9 , Issue.12 , pp. 1143-1152
    • Bax, B.1    Carter, P.S.2    Lewis, C.3    Guy, A.R.4    Bridges, A.5    Tanner, R.6    Pettman, G.7    Mannix, C.8    Culbert, A.A.9    Brown, M.J.B.10    Smith, D.G.11    Reith, A.D.12
  • 2
    • 0025286104 scopus 로고
    • Molecular cloning and expression of glycogen synthase kinase-3/factor A
    • Woodgett, J. R. (1990) Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J. 9, 2431-2438
    • (1990) EMBO J. , vol.9 , pp. 2431-2438
    • Woodgett, J.R.1
  • 3
    • 0032989714 scopus 로고    scopus 로고
    • Developmental expression and localization of glycogen synthase kinase-3β in rat brain
    • DOI 10.1016/S0891-0618(99)00012-5, PII S0891061899000125
    • Leroy, K., and Brion, J. P. (1999) Developmental expression and localization of glycogen synthase kinase-3β in rat brain. J. Chem. Neuroanat. 16, 279-293 (Pubitemid 29296952)
    • (1999) Journal of Chemical Neuroanatomy , vol.16 , Issue.4 , pp. 279-293
    • Leroy, K.1    Brion, J.-P.2
  • 4
    • 33748299477 scopus 로고    scopus 로고
    • The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways
    • DOI 10.1016/j.pneurobio.2006.07.006, PII S0301008206000797
    • Beurel, E., and Jope, R. S. (2006) The paradoxical pro- and anti-apoptotic actions of GSK-3 in the intrinsic and extrinsic apoptosis signaling pathways. Prog. Neurobiol. 79, 173-189 (Pubitemid 44331500)
    • (2006) Progress in Neurobiology , vol.79 , Issue.4 , pp. 173-189
    • Beurel, E.1    Jope, R.S.2
  • 5
    • 0032493729 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in the phosphatidylinositol 3- kinase/Akt cell survival pathway
    • DOI 10.1074/jbc.273.32.19929
    • Pap, M., and Cooper, G. M. (1998) Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway. J. Biol. Chem. 273, 19929-19932 (Pubitemid 28377539)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.32 , pp. 19929-19932
    • Pap, M.1    Cooper, G.M.2
  • 6
    • 0034175688 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3β in neuronal apoptosis induced by trophic withdrawal
    • Hetman, M., Cavanaugh, J. E., Kimelman, D., and Xia, Z. (2000) Role of glycogen synthase kinase-3β in neuronal apoptosis induced by trophic withdrawal. J. Neurosci. 20, 2567-2574 (Pubitemid 30220344)
    • (2000) Journal of Neuroscience , vol.20 , Issue.7 , pp. 2567-2574
    • Hetman, M.1    Cavanaugh, J.E.2    Kimelman, D.3    Zhengui, X.4
  • 7
    • 33747425620 scopus 로고    scopus 로고
    • GSK-3 is essential in the pathogenesis of Alzheimer disease
    • Takashima, A. (2006) GSK-3 is essential in the pathogenesis of Alzheimer disease. J. Alzheimers Dis. 9, 309-317
    • (2006) J. Alzheimers Dis. , vol.9 , pp. 309-317
    • Takashima, A.1
  • 8
    • 9444257518 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β (GSK3η) mediates 6-hydroxydopamine- induced neuronal death
    • DOI 10.1096/fj.04-1551fje
    • Chen, G., Bower, K. A., Ma, C., Fang, S., Thiele, C. J., and Luo, J. (2004) Glycogen synthase kinase 3β (GSK-3β) mediates 6-hydroxydopamine-induced neuronal death. FASEB J. 18, 1162-1164 (Pubitemid 39561557)
    • (2004) FASEB Journal , vol.18 , Issue.10 , pp. 1162-1164
    • Chen, G.1    Bower, K.A.2    Ma, C.3    Fang, S.4    Thiele, C.J.5    Luo, J.6
  • 10
    • 34249689633 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3β protects dopaminergic neurons from MPTP toxicity
    • DOI 10.1016/j.neuropharm.2007.03.017, PII S0028390807000962
    • Wang, W., Yang, Y., Ying, C., Li, W., Ruan, H., Zhu, X., You, Y., Han, Y., Chen, R., Wang, Y., and Li, M. (2007) Inhibition of glycogen synthase kinase-3β protects dopaminergic neurons from MPTP toxicity. Neuropharmacology 52, 1678-1684 (Pubitemid 46843143)
    • (2007) Neuropharmacology , vol.52 , Issue.8 , pp. 1678-1684
    • Wang, W.1    Yang, Y.2    Ying, C.3    Li, W.4    Ruan, H.5    Zhu, X.6    You, Y.7    Han, Y.8    Chen, R.9    Wang, Y.10    Li, M.11
  • 11
    • 20444394386 scopus 로고    scopus 로고
    • Inhibition of GSK3β is a common event in neuroprotection by different survival factors
    • DOI 10.1016/j.molbrainres.2005.03.004, PII S0169328X05001154
    • Chin, P. C., Majdzadeh, N., and D'Mello, S. R. (2005) Inhibition of GSK-3βis a common event in neuroprotection by different survival factors. Mol. Brain Res. 137, 193-201 (Pubitemid 40798902)
    • (2005) Molecular Brain Research , vol.137 , Issue.1-2 , pp. 193-201
    • Chin, P.C.1    Majdzadeh, N.2    D'Mello, S.R.3
  • 12
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • Cross, D. A., Alessi, D. R., Cohen, P., Andjelkovich, M., and Hemmings, B. A. (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378, 785-789 (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 13
    • 0034461612 scopus 로고    scopus 로고
    • Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3β
    • DOI 10.1128/MCB.20.24.9356-9363.2000
    • Li, M., Wang, X., Meintzer, M. K., Laessig, T., Birnbaum, M. J., and Heidenreich, K. A. (2000) Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3β. Mol. Cell. Biol. 20, 9356-9363 (Pubitemid 32246120)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.24 , pp. 9356-9363
    • Li, M.1    Wang, X.2    Meintzer, M.K.3    Laessig, T.4    Birnbaum, M.J.5    Heidenreich, K.A.6
  • 14
    • 78650367828 scopus 로고    scopus 로고
    • Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival
    • Song, B., Lai, B., Zheng, Z., Zhang, Y., Luo, J., Wang, C., Chen, Y., Woodgett, J. R., and Li, M. (2010) Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival. J. Biol. Chem. 285, 41122-41134
    • (2010) J. Biol. Chem. , vol.285 , pp. 41122-41134
    • Song, B.1    Lai, B.2    Zheng, Z.3    Zhang, Y.4    Luo, J.5    Wang, C.6    Chen, Y.7    Woodgett, J.R.8    Li, M.9
  • 15
    • 0035875098 scopus 로고    scopus 로고
    • Crystal structure of glycogen synthase kinase 3β: Structural basis for phosphate-primed substrate specificity and autoinhibition
    • DOI 10.1016/S0092-8674(01)00374-9
    • Dajani, R., Fraser, E., Roe, S. M., Young, N., Good, V., Dale, T. C., and Pearl, L. H. (2001) Crystal structure of glycogen synthase kinase 3β. Structural basis for phosphate-primed substrate specificity and autoinhibition. Cell 105, 721-732 (Pubitemid 32635102)
    • (2001) Cell , vol.105 , Issue.6 , pp. 721-732
    • Dajani, R.1    Fraser, E.2    Roe, S.M.3    Young, N.4    Good, V.5    Dale, T.C.6    Pearl, L.H.7
  • 17
    • 34547929974 scopus 로고    scopus 로고
    • N-terminal cleavage of GSK-3 by calpain. A new form of GSK-3 regulation
    • Goñi-Oliver, P., Lucas, J. J., Avila, J., and Hernández, F. (2007) N-terminal cleavage of GSK-3 by calpain. A new form of GSK-3 regulation. J. Biol. Chem. 282, 22406-22413
    • (2007) J. Biol. Chem. , vol.282 , pp. 22406-22413
    • Goñi-Oliver, P.1    Lucas, J.J.2    Avila, J.3    Hernández, F.4
  • 18
    • 65949119740 scopus 로고    scopus 로고
    • Calpain-mediated truncation of GSK-3 in post-mortem brain samples
    • Goñi-Oliver, P., Avila, J., and Hernández, F. (2009) Calpain-mediated truncation of GSK-3 in post-mortem brain samples. J. Neurosci. Res. 87, 1156-1161
    • (2009) J. Neurosci. Res. , vol.87 , pp. 1156-1161
    • Goñi-Oliver, P.1    Avila, J.2    Hernández, F.3
  • 19
    • 74949097238 scopus 로고    scopus 로고
    • Memantine inhibits calpain-mediated truncation of GSK-3 induced by NMDA. Implications in Alzheimer disease
    • Goñi-Oliver, P., Avila, J., and Hernández, F. (2009) Memantine inhibits calpain-mediated truncation of GSK-3 induced by NMDA. Implications in Alzheimer disease. J. Alzheimers Dis. 18, 843-848
    • (2009) J. Alzheimers Dis. , vol.18 , pp. 843-848
    • Goñi-Oliver, P.1    Avila, J.2    Hernández, F.3
  • 21
    • 79955707098 scopus 로고    scopus 로고
    • Egr-1 transactivates Bim gene expression to promote neuronal apoptosis
    • Xie, B., Wang, C., Zheng, Z., Song, B., Ma, C., Thiel, G., and Li, M. (2011) Egr-1 transactivates Bim gene expression to promote neuronal apoptosis. J. Neurosci. 31, 5032-5044
    • (2011) J. Neurosci. , vol.31 , pp. 5032-5044
    • Xie, B.1    Wang, C.2    Zheng, Z.3    Song, B.4    Ma, C.5    Thiel, G.6    Li, M.7
  • 23
    • 35648958679 scopus 로고    scopus 로고
    • dp5/HRK is a c-jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons
    • DOI 10.1074/jbc.M608694200
    • Ma, C., Ying, C., Yuan, Z., Song, B., Li, D., Liu, Y., Lai, B., Li, W., Chen, R., Ching, Y. P., and Li, M. (2007) dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons. J. Biol. Chem. 282, 30901-30909 (Pubitemid 350035234)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.42 , pp. 30901-30909
    • Ma, C.1    Ying, C.2    Yuan, Z.3    Song, B.4    Li, D.5    Liu, Y.6    Lai, B.7    Li, W.8    Chen, R.9    Ching, Y.-P.10    Li, M.11
  • 25
    • 68049086885 scopus 로고    scopus 로고
    • Calpain-truncated CRMP-3 and -4 contribute to potassium deprivation-induced apoptosis of cerebellar granule neurons
    • Liu, W., Zhou, X. W., Liu, S., Hu, K., Wang, C., He, Q., and Li, M. (2009) Calpain-truncated CRMP-3 and -4 contribute to potassium deprivation-induced apoptosis of cerebellar granule neurons. Proteomics 9, 3712-3728
    • (2009) Proteomics , vol.9 , pp. 3712-3728
    • Liu, W.1    Zhou, X.W.2    Liu, S.3    Hu, K.4    Wang, C.5    He, Q.6    Li, M.7
  • 26
    • 0029909560 scopus 로고    scopus 로고
    • Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells
    • Miller, T. M., and Johnson, E. M., Jr. (1996) Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells. J. Neurosci. 16, 7487-7495 (Pubitemid 26389687)
    • (1996) Journal of Neuroscience , vol.16 , Issue.23 , pp. 7487-7495
    • Miller, T.M.1    Johnson Jr., E.M.2
  • 27
    • 34247490197 scopus 로고    scopus 로고
    • Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons
    • DOI 10.1016/j.neuroscience.2007.01.042, PII S0306452207000802
    • Alvira, D., Tajes, M., Verdaguer, E., de Arriba, S. G., Allgaier, C., Matute, C., Trullas, R., Jiménez, A., Pallàs, M., and Camins, A. (2007) Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons. Neuroscience 146, 350-365 (Pubitemid 46654625)
    • (2007) Neuroscience , vol.146 , Issue.1 , pp. 350-365
    • Alvira, D.1    Tajes, M.2    Verdaguer, E.3    De Arriba, S.G.4    Allgaier, C.5    Matute, C.6    Trullas, R.7    Jimenez, A.8    Pallas, M.9    Camins, A.10
  • 30
    • 0142039820 scopus 로고    scopus 로고
    • Alleviating the Suppression of Glycogen Synthase Kinase-3β by Akt Leads to the Phosphorylation of cAMP-response Element-binding Protein and Its Transactivation in Intact Cell Nuclei
    • DOI 10.1074/jbc.M302972200
    • Salas, T. R., Reddy, S. A., Clifford, J. L., Davis, R. J., Kikuchi, A., Lippman, S. M., and Menter, D. G. (2003) Alleviating the suppression of glycogen synthase kinase-3β by Akt leads to the phosphorylation of cAMP-response element-binding protein and its transactivation in intact cell nuclei. J. Biol. Chem. 278, 41338-41346 (Pubitemid 37280963)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.42 , pp. 41338-41346
    • Salas, T.R.1    Reddy, S.A.2    Clifford, J.L.3    Davis, R.J.4    Kikuchi, A.5    Lippman, S.M.6    Menter, D.G.7
  • 32
    • 14644435825 scopus 로고    scopus 로고
    • Intrinsically unstructured proteins and their functions
    • DOI 10.1038/nrm1589
    • Dyson, H. J., and Wright, P. E. (2005) Intrinsically unstructured proteins and their functions. Nat. Rev. Mol. Cell Biol. 6, 197-208 (Pubitemid 40314921)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.3 , pp. 197-208
    • Dyson, H.J.1    Wright, P.E.2
  • 33
    • 3242891318 scopus 로고    scopus 로고
    • The DISOPRED server for the prediction of protein disorder
    • DOI 10.1093/bioinformatics/bth195
    • Ward, J. J., McGuffin, L. J., Bryson, K., Buxton, B. F., and Jones, D. T. (2004) The DISOPRED server for the prediction of protein disorder. Bioinformatics 20, 2138-2139 (Pubitemid 39236567)
    • (2004) Bioinformatics , vol.20 , Issue.13 , pp. 2138-2139
    • Ward, J.J.1    McGuffin, L.J.2    Bryson, K.3    Buxton, B.F.4    Jones, D.T.5
  • 36
  • 37
    • 13844255387 scopus 로고    scopus 로고
    • Natively unfolded proteins
    • Fink, A. L. (2005) Natively unfolded proteins. Curr. Opin. Struct. Biol. 15, 35-41
    • (2005) Curr. Opin. Struct. Biol. , vol.15 , pp. 35-41
    • Fink, A.L.1
  • 38
    • 79960343311 scopus 로고    scopus 로고
    • Calpain regulates N-terminal interaction of GSK-3β with 14-3-3ζ, p53, and PKB but not with axin
    • Goñi-Oliver, P., Avila, J., and Hernández, F. (2011) Calpain regulates N-terminal interaction of GSK-3β with 14-3-3ζ, p53, and PKB but not with axin. Neurochem. Int. 59, 97-100
    • (2011) Neurochem. Int. , vol.59 , pp. 97-100
    • Goñi-Oliver, P.1    Avila, J.2    Hernández, F.3
  • 39
    • 34447498406 scopus 로고    scopus 로고
    • The phosphorylation state of GluR1 subunits determines the susceptibility of AMPA receptors to calpain cleavage
    • DOI 10.1074/jbc.M701283200
    • Yuen, E. Y., Liu, W., and Yan, Z. (2007) The phosphorylation state of GluR1 subunits determines the susceptibility of AMPA receptors to calpain cleavage. J. Biol. Chem. 282, 16434-16440 (Pubitemid 47100393)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 16434-16440
    • Yuen, E.Y.1    Liu, W.2    Yan, Z.3
  • 41
    • 0023323994 scopus 로고
    • A unique specificity of a calcium-activated neutral protease indicated in histone hydrolysis
    • Sakai, K., Akanuma, H., Imahori, K., and Kawashima, S. (1987) A unique specificity of a calcium-activated neutral protease indicated in histone hydrolysis. J. Biochem. 101, 911-918
    • (1987) J. Biochem. , vol.101 , pp. 911-918
    • Sakai, K.1    Akanuma, H.2    Imahori, K.3    Kawashima, S.4
  • 42
    • 53749096967 scopus 로고    scopus 로고
    • Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration
    • Vosler, P. S., Brennan, C. S., and Chen, J. (2008) Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration. Mol. Neurobiol. 38, 78-100
    • (2008) Mol. Neurobiol. , vol.38 , pp. 78-100
    • Vosler, P.S.1    Brennan, C.S.2    Chen, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.