Coordinate deletion of N-glycans from the heptad repeats of the fusion F protein of newcastle disease virus yields a hyperfusogenic virus with increased replication, virulence, and immunogenicity

Journal of Virology

Volumn 86, Issue 5, 2012, Pages 2501-2511

  Samal, Sweety ^a   Khattar, Sunil K ^a   Kumar, Sachin ^a   Collins, Peter L ^b   Samal, Siba K ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; GLUTAMINE; GLYCAN; PROTEIN F; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CHICKEN; CONTROLLED STUDY; EMBRYO; GLYCOSYLATION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNOGENICITY; IN VITRO STUDY; MUTANT; MUTATION; NEWCASTLE DISEASE PARAMYXOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REVERSE GENETICS; VIRAL TROPISM; VIROGENESIS; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; ANTIBODIES, VIRAL; CHICKENS; GLYCOSYLATION; NEWCASTLE DISEASE; NEWCASTLE DISEASE VIRUS; POULTRY DISEASES; REPETITIVE SEQUENCES, NUCLEIC ACID; SEQUENCE DELETION; VIRAL FUSION PROTEINS; VIRULENCE; VIRUS REPLICATION;

GALLUS GALLUS; NEWCASTLE DISEASE VIRUS;

EID: 84863297321     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06380-11     Document Type: Article

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