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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 6, 2012, Pages 2287-2290

Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1)

(18) Harikrishnan, Lalgudi S a Srivastava, Neelam a Kayser, Lauren E a Nirschl, David S a K, Kumaragurubaran b Roy, Amrita b Gupta, Anuradha b Karmakar, Sukhen b Karatt, Tajudheen b Mathur, Arvind a Burford, Neil T a Chen, Jing a Kong, Yan a Cvijic, Maryellen a Cooper, Christopher B a Poss, Michael A a Trainor, George L a Wong, Tai W a

a BRISTOL MYERS SQUIBB (United States)

b SYNGENE INTERNATIONAL LTD (India)

Author keywords

Vasoactive intestinal peptide (VIP); Vasoactive intestinal peptide receptor (VIPR)

Indexed keywords

UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE ANTAGONIST; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 ANTAGONIST;

ARTICLE; CELL PROLIFERATION; DOSE RESPONSE; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; RECEPTORS, VASOACTIVE INTESTINAL POLYPEPTIDE, TYPE I; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 84863282965 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.01.082 Document Type: Article

Times cited : (8)

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