Correlation between antimetastatic action of Ajuga decumbens and expression of MMPs and TIMPs

Zhongguo Zhongyao Zazhi

Volumn 36, Issue 24, 2011, Pages 3511-3514

  Peng, Bo ^a   He, Rong ^a   Xu, Qihua ^a   Gao, Jie ^a   Lu, Yanli ^a   Li, Jianrong ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Ajuga decumbens; Breast cancer; Matrix metalloprotinases; Tissue inhibitors of metalloproteinases

Indexed keywords

AJUGA DECUMBEN EXTRACT; GELATINASE A; GELATINASE B; PLANT EXTRACT; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; LUNG TUMOR; METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PROTEIN EXPRESSION; TUMOR VOLUME; UPREGULATION; WESTERN BLOTTING;

AJUGA; ANIMALS; FEMALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METALLOPROTEASES; MICE; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHYTOTHERAPY; PLANT EXTRACTS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 84863279523     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20112427     Document Type: Article

References (13)

1. Midori Takasaki, Harukuni Tokuda, Hoyoku Nishino, et al. Cancer cheraopreventive agents (antitumor-promoters) from Ajuga decumbens[J]. J Nat Prod, 1999,62(7):972.
2. Midori Takasaki, Isao Yamauchi, Mitsumasa Haruna, et al. New glycosides from Ajuga decumbens[J]. J Nat Prod, 1998,61(9):1105.
3. Konoshima T, Takasaki M, Tokuda H, et al. Cancer chemopreventive activity of an iridoidglycoside, 8-acetylharpagide, from Ajuga decumbens[J]. Cancer Lett, 2000,157(1):87.
4. Sivula A, Talvensaari-Mattila A, Lundin J, et al. Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer[J]. Breast Cancer Res Treat, 2005,89:215.
5. Têtu B, Brisson J, Wang C S, et al. The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis[J]. Breast Cancer Res, 2006,8(3):R28.
6. Kuvaja P, Würtz S, Talvensaari-Mattila A, et al. High serum TIMP-1 correlates with poor prognosis in breast carcinoma-avali-dation study[J]. Cancer Biomark, 2007,3(6):293.
7. Nakopoulou L, Tsirmpa I, Alexandrou P, et al. MMP-2 protein in invasive breast cancer and the impact of MMP-2/T1MP-2 phenotype on overall survival[J]. Breast Cancer Res Treat, 2003,77(2):145.
8. Kousidou O C, Roussidis A E, Theocharis A D, et al. Expression of MMPs and TIMPs genes in human breast cancer epithelial ceils depends on cell culture conditions and is associated with their invasive potential[J]. Anticancer Res, 2004,24(6):4025.