Characterization of Korean traditional medicine Chongmyungtang for cognitive function related to anti-cholinesterases and antioxidant activity

Food Science and Biotechnology

Volumn 20, Issue 5, 2011, Pages 1331-1336

  Lee, Mi Ra ^a   Yun, Beom Sik ^a   Oh, Chang Jin ^a   Kim, Byung Chan ^a   Oh, Hyun In ^b   Sung, Chang Keun ^a  

^a Chungnam National University   (South Korea)

^b Korea Food Research Institute   (South Korea)

Author keywords

acetylcholinesterase; butyrylcholinesterase; chongmyungtang; memory; scopolamine

Indexed keywords

ACETYLCHOLINESTERASE; BUTYRYLCHOLINESTERASE; CHONGMYUNGTANG; MEMORY; SCOPOLAMINE;

PHENOLS;

PLANTS (BOTANY);

ACORUS; ACORUS GRAMINEUS; MUS; POLYGALA TENUIFOLIA; PORIA COCOS;

EID: 84863268370     PISSN: 12267708     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10068-011-0183-6     Document Type: Article

References (30)

1. Cummings BJ, Pike CJ, Shankle R, Cotman CW. β-Amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiol. Aging 17: 921-933 (1996).
2. Bartus RT. On neurodegenerative disease, models, and treatment strategies: Lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Exp. Neurol. 163: 495-529 (2000).
3. Ohno K, Tsujino A, Brengman JM, Harper CM, Bajzer Z, Udd B, Beyring R, Robb S, Kirkham FJ, Engel AG. Choline acetyltransferase mutations cause myasthenic syndrome associated with episodic apnea in humans. P. Natl. Acad. Sci. USA 98: 2017-2022 (2001).
4. Ballard CG, Greig NH, Guillozet-Bongaarts AL, Enz A, Darvesh S. Cholinesterases: Roles in the brain during health and disease. Curr. Alzheimer Res. 2: 307-318 (2005).
5. Wright CI, Geula C, Mesulam MM. Neurological cholinesterases in the normal brain and in Alzheimer's disease: Relationship to plaques, tangles, and patterns of selective vulnerability. Ann. Neurol. 34: 373-384 (1993).
6. Heinrich M, Teoh HL. Galanthamine from snowdrop-the development of a modern drug against Alzheimer's disease from local Caucasian knowledge. J. Ethnopharmacol. 92: 147-162 (2004).
7. Sculz V. Ginkgo extract or cholinesterase inhibitors in patients with dementia: What clinical trial and guidelines fail to consider. Phytomedicine 10: 74-79 (2003).
8. Perry NSL, Houghton PJ, Sampson J, Theobald AE, Hart S, Lis-Balchin M, Hoult JR, Evans P, Jenner P, Milligan S, Perry EK. Invitro activity of S. lavandulaefolia (Spanish sage) relevant to treatment of Alzheimer's disease. J. Pharm. Pharmacol. 53: 1347-1356 (2001).
9. Lee MR, Yun BS, Park SY, Ly SY, Kim SN, Han BH, Sung CK. Anti-amnesic effect of chongmyungtang on scopolamine-induced memory impairments in mice. J. Ethnopharmacol. 132: 70-74 (2010).
10. Zhang Y, Saito H, Nishiyama N. Improving effects of DX-9386, a traditional Chinese medicinal prescription, on thymectomy-induced impairment of learning behaviors in mice. Biol. Pharm. Bull. 17: 1199-1205 (1994).
11. Cho JS, Joo NE, Kong JY, Jeong DY, Lee KD, Kang BS. Inhibition of excitotoxic neuronal death by methanol extract of Acori graminei rhizoma in cultured rat cortical neurons. J. Ethnopharmacol. 73: 31-37 (2000).
12. Cho J, Kim YH, Kang JY, Yang CH, Park CG. Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus. Life Sci. 71: 591-599 (2002).
13. Chen YL, Hsich CL, Wu PHB, Lin JG. Effect of Polygala tenuifolia root on behavioral disorders by lesioning nucleus basalis magnocellularis in rat. J. Ethnopharmacol. 95: 47-55 (2004).
14. Okui Y, Morita M, Iizuka A, Komatsu Y, Okada M, Maruno M, Niijima A. Effects of hoelen on the efferent activity of the gastric vagus nerve in the rat. Jpn. J. Pharmacol. 72: 71-73 (1996).
15. Shiada Y, Yokoyama K, Goto H, Sekiya N, Mantani N, Tahara E, Hikiami H, Terasawa K. Protective effect of Keishi-bukuryo-gan and its constituent medicinal plants against nitric oxide donorinduced neuronal death in cultured cerebellar granule cells. Phytomedicine 11: 404-410 (2004).
16. Ellman GL, Courtney KD, Andres Jr V, Feather-Stone RM. A new and rapid colormetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 7: 88-95 (1961).
17. Singleton VL, Rossi JA Jr. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am. J. Enol. Viticult. 16: 144-158 (1965).
18. Blois MS. Antioxidant determinations by the use of a stable free radical. Nature 181: 1199-1202 (1958).
19. Inestrosa NC, Alvarez A, Godoy J, Reyes A, De Ferrari GV. Acetylcholinesterase amyloid-β-peptide interaction and Wnt signaling involvement in neurotoxicity. Acta Neurol. Scand. 173: 53-59 (2000).
20. Hodges JR. Alzheimer's centennial legacy: Origins, landmarks, and the current status of knowledge concerning cognitive aspects. Brain 129: 2811-2822 (2006).
21. Giacobini E. Cholinesterase inhibitors from the Calabar bean to Alzheimer therapy. pp. 181-226. In: Cholinesterases and Cholinesterase Inhibitors. Giacobini E (ed). Martin Dunitz, London, UK (2000).
22. Park CH, Choi SH, Koo JW, Seo JH, Kim HS, Jeong SJ, Suh YH. Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11. J. Neurosci. Res. 70: 484-492 (2002).
23. Oyaizu M. Studies on product of browning reaction prepared from glucose amine. Jpn. J. Nutr. 44: 307-315 (1986).
24. Soares JR, Dins TCP, Cunha AP, Ameida LM. Antioxidant activity of some extracts of Thymus zygis. Free Radical Res. 26: 469-478 (1997).
25. Marcus DL, Thomas C, Rodriquez C, Simberkoff K, Tsai JS, Strafaci JA, Freedman ML. Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease. Exp. Neurol. 150: 40-44 (1998).
26. Tang SY, Whiteman M, Peng ZF, Jenner A, Yong EL, Halliwell B. Characterization of antioxidant and antiglycation properties and isolation of active ingredients from traditional Chinese medicines. Free Radical Bio. Med. 36: 1575-1587 (2004).
27. Rice-Evans CA, Miller NJ, Paganga G. Antioxidants properties of phenolic compounds. Trends Plant Sci. 2: 152-159 (1997).
28. Troster AI, Beatty WW, Staton RD, Rorabaugh AG. Effect of scopolamine on anterograde and remote memory in humans. Psychobiology 17: 12-18 (1989).
29. Ebert U, Kirch W. Scopolamine model of dementia: Electroencephalogram findings and cognitive performance. Eur. J. Clin. Invest. 28: 944-949 (1998).
30. Lee B, Choi Y, Kim H, Kim SY, Hahm DH, Lee HJ, Shim I. Protective effects of methanol extract of Acori graminei rhizoma and Uncariae Ramulus et Uncus on ischemia-induced neuronal death and cognitive impairments in the rat. Life Sci. 74: 435-450 (2003).