High-sodium intake aggravates myocardial injuries induced by aldosterone via oxidative stress in Sprague-Dawley rats

Acta Pharmacologica Sinica

Volumn 33, Issue 3, 2012, Pages 393-400

  Li, Jing Yi ^a,b   Yan, Li ^a   Zhang, Shao Ling ^a   Ren, Meng ^a   Wen, Yan Ling ^a   Cheng, Hua ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

aldosterone; blood pressure; left ventricular hypertrophy; myocardial injury; oxidative stress; sodium intake

Indexed keywords

ALDOSTERONE; COLLAGEN; INTERLEUKIN 18; PROTEIN P22; PROTEIN P47;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE FIBROSIS; HEART MUSCLE INJURY; HIGH SODIUM INTAKE; HYPERTENSION; MALE; NONHUMAN; OSMOTIC MINIPUMP; OXIDATIVE STRESS; RAT; SODIUM INTAKE; SPRAGUE DAWLEY RAT; TRANSMISSION ELECTRON MICROSCOPY; TRANSTHORACIC ECHOCARDIOGRAPHY; WESTERN BLOTTING;

ALDOSTERONE; ANIMALS; DRUG SYNERGISM; HEART; MALE; MYOCARDIUM; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM, DIETARY;

EID: 84863260554     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.179     Document Type: Article

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