Comparative gene expression analysis between coronary arteries and internal mammary arteries identifies a role for the TES gene in endothelial cell functions relevant to coronary artery disease

Human Molecular Genetics

Volumn 21, Issue 6, 2012, Pages 1364-1373

  Archacki, Stephen R ^a,b   Angheloiu, George ^a   Moravec, Christine S ^a,b   Liu, Hui ^c   Topol, Eric J ^d   Wang, Qing Kenneth ^a,b,c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b Geological Environmental Sciences   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; METHYLTESTOSTERONE; OXIDIZED LOW DENSITY LIPOPROTEIN; SMALL INTERFERING RNA;

ADULT; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DOWN REGULATION; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; INTERNAL MAMMARY ARTERY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MICROARRAY ANALYSIS; MONOCYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APOPTOSIS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CORONARY ARTERY DISEASE; CORONARY VESSELS; CYTOSKELETAL PROTEINS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION PROFILING; HUMANS; LIM DOMAIN PROTEINS; MAMMARY ARTERIES; MONOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84863253567     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr574     Document Type: Article

References (20)

1. Deaths and percentage of total death for the 10 leading causes of death: (2007) United States, 2002-2003 (PDF). National Center of Health Statistics, Retrieved on April 17.
2. Raja, S.G., Haider, Z., Ahmad, M. and Zaman, H. (2004) Saphenous vein grafts: to use or not to use? Heart Lung Circ., 13, 403-409.
3. Loop, F.D. (1996) Internal-thoracic-artery grafts. Biologically better coronary arteries. N. Engl. J. Med., 334, 263-265.
4. Boylan, M.J., Lytle, B.W., Loop, F.D., Taylor, P.C., Borsh, J.A., Goormastic, M. and Cosgrove, D.M. (1994) Surgical treatment of isolated left anterior descending coronary stenosis. Comparison of left internal mammary artery and venous autograft at 18 to 20 years of follow-up. J. Thorac. Cardiovasc. Surg., 107, 657-662.
5. Ojha, M., Leask, R.L., Johnston, K.W., David, T.E. and Butany, J. (2000) Histology and morphology of 59 internal thoracic artery grafts and their distal anastomoses. Ann. Thorac. Surg., 70, 1338-1344.
6. O'Keefe, J.H. Jr, Kreamer, T.R., Jones, P.G., Vacek, J.L., Gorton, M.E., Muehlebach, G.F., Rutherford, B.D. and McCallister, B.D. (1999) Isolated left anterior descending coronary artery disease. percutaneous transluminal coronary angioplasty versus stenting versus left internal mammary artery bypass grafting. Circulation, 100, 114-118.
7. Loop, F.K., Lytle, B.W., Cosgrove, D.M., Stewart, R.W., Goormastic, M., Williams, G.W., Golding, L.A., Gill, C.C., Taylor, P.C. and Sheldon, W.C. (1986) Influence of the internal-mammary graft on 10-year survival and other cardiac events. N. Engl. J. Med., 314, 1-6.
8. Drusco, A., Zanesi, N., Roldo, C., Trapasso, F., Farber, J.L., Fong, L.Y. and Croce, C.M. (2005) Knockout mice reveal a tumor suppressor function for Testin. Proc. Natl Acad. Sci. USA, 102, 10947-10951.
9. Grima, J., Wong, C.C., Zhu, L.J., Zong, S.D. and Cheng, C.Y. (1998) Testin secreted by Sertoli cells is associated with the cell surface, and its expression correlates with the disruption of Sertoli-germ cell junctions but not the inter-Sertoli tight junction. J. Biol. Chem., 273, 21040-21053.
10. Lusis, A.J. (2000) Atherosclerosis. Nature, 407, 233-241.
11. Grima, J., Zhu, L. and Cheng, C.Y. (1997) Testin is tightly associated with testicular cell membrane upon its secretion by sertoli cells whose steady-state mRNA level in the testis correlates with the turnover and integrity of inter-testicular cell junctions. J. Biol. Chem., 272, 6499-6509.
12. Cheng, C.Y. and Bardin, C.W. (1987) Identification of two testosterone-responsive testicular proteins in Sertoli cell-enriched culture medium whose secretion is suppressed by cells of the intact seminiferous tubule. J. Biol. Chem., 262, 12768-12779.
13. Boëda, B., Briggs, D.C., Higgins, T., Fadden, A.J., McDonald, N.Q. and Way, M. (2007) Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding. Mol. Cell, 28, 1071-1082.
14. Qin, M., Zeng, Z., Zheng, J., Sha, P.K., Schwartz, S.M., Adams, L.D. and Sharifi, B.G. (2003) Suppression subtractive hybridization identifies distinctive expression markers for coronary and internal mammary arteries. Arterioscler. Thromb. Vasc. Biol., 23, 425-433.
15. Romanoski, C.E., Che, N., Yin, F., Mai, N., Pouldar, D., Civelek, M., Pan, C., Lee, S., Vakili, L., Yang, W.P. et al. (2011) Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1. Circ. Res., 109, e27-e41.
16. Shiffman, D., Ellis, S.G., Rowland, C.M., Malloy, M.J., Luke, M.M., Iakoubova, O.A., Pullinger, C.R., Cassano, J., Aouizerat, B.E., Fenwick, R.G. et al. (2005) Identification of four gene variants associated with myocardial infarction. Am. J. Hum. Genet., 77, 596-605.
17. Yasojima, K., McGeer, E.G. and McGeer, P.L. (2001) High stability of mRNAs postmortem and protocols for their assessment by RT-PCR, Brain Res. Brain Res. Protoc., 8, 212-218.
18. Moravec, C.S., Schluchter, M.D., Paranandi, L., Czerska, B., Stewart, R.W., Rosenkranz, E. and Bond, M. (1990) Inotropic effects of angiotensin II in human cardiac muscle in vitro. Circulation, 82, 1973-1984.
19. Archacki, S.R., Angheloiu, G., Tian, X.L., Tan, F.L., DiPaola, N., Shen, G.Q., Moravec, C., Ellis, S., Topol, E.J. and Wang, Q. (2003) Identification of new genes differentially expressed in coronary artery disease by expression profiling. Physiol. Genomics, 15, 65-74.
20. You, S.A., Archacki, S.R., Angheloiu, G., Moravec, C.S., Rao, S., Kinter, M., Topol, E.J. and Wang, Q. (2003) Proteomic approach to coronary atherosclerosis shows ferritin light chain as a significant marker: evidence consistent with iron hypothesis in atherosclerosis. Physiol. Genomics, 18, 25-30.