Characterization of immune response in mice induced by recombinant vaccinia virus(Tiantan) based multivalent H5N1 avian influenza vaccines

Chinese Journal of Microbiology and Immunology

Volumn 30, Issue 6, 2010, Pages 546-550

  Wang, Wen ^a   Deng, Yao ^b   Tan, Wen Jie ^a,b   Chen, Hong ^a   Wang, Min ^a   Yin, Xiao ^a   Guan, Jie ^a   Zhou, Jian Fang ^a,b   Shu, Yue Long ^a,b   Ruan, Li ^a  

^a NATIONAL INSTITUTE FOR VIRAL DISEASE CONTROL AND PREVENTION   (China)

^b State Key Laboratory for Molecular Virology and Genetic Engineering   (China)

Author keywords

H5N1; Highly pathogenic avian influenza (HPAI) virus; Live viral vector based vaccine; Recombinant vaccinia (Tiantan) virus

Indexed keywords

GAMMA INTERFERON; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; NEUTRALIZING ANTIBODY; RECOMBINANT VACCINE; RECOMBINANT VACCINIA VIRUS TIANTAN VACCINE; SIALIDASE; UNCLASSIFIED DRUG; VACCINIA VACCINE;

ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; HUMORAL IMMUNITY; IMMUNE RESPONSE; INFLUENZA VIRUS A H5N1; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SINGLE DRUG DOSE; VIRUS STRAIN;

EID: 84863246291     PISSN: 02545101     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0254-5101.2010.06.014     Document Type: Article

References (18)

1. Tsao H, Liu G Q, Ruan L, et al. Construction and application of plasmids containing bidirectional promoters of vaccinia virus. J Virol, 1988, 62(12):4832-4834.
2. Shu Y, Yu H, Li D. Lethal avian influenza A (H5N1) infection in a pregnant woman in Anhui Province, China. N Engl J Med, 2006, 354(13): 1421-1422.
3. 2008, 24(6): 415-420.
4. Yan K, Tan W, Wang H, et al. SARS-CoV spike proteins expressed by the vaccinia virus Tiantan strain: secreted sq protein induces robust neutralization antibody in mice. Viral Immunol, 2009, 22(1): 57-66.
5. 1997.
6. Temperton N J, Hoschler K, Major D, et al. A sensitive retroviral pseudotype assay for influenza H5N1-neutralizing antibodies. Influenza Other Respi Viruses, 2007, 1(3): 105-112.
7. 2008, 24(4): 287-294.
8. Deng Y, Zhang K, Tan W, et al. A recombinant DNA and vaccinia virus prime-boost regimen induces potent long-term T-cell responses to HCV in BALB/c mice. Vaccine, 2009, 27 (15): 2085-2088.
9. Gambotto A, Barratt-Boyes S M, de Jong M D, et al. Human infection with highly pathogenic H5N1 influenza virus. Lancet, 2008, 371(9622): 1464-1475.
10. Subbarao K, Luke C. H5N1 viruses and vaccines. PLoS Pathog, 2007, 3(3): e40.
11. Kreijtz J H, Suezer Y, van Amerongen G, et al. Recombinant modified vaccinia virus Ankara-based vaccine induces protective immunity in mice against infection with influenza virus H5N1. J Infect Dis, 2007, 195(11): 1598-1606.
12. Kreijtz J H, Suezer Y, de Mutsert G, et al. Recombinant modified vaccinia virus Ankara expressing the hemagglutinin gene confers protection against homologous and heterologous H5N1 influenza virus infections in macaques. J Infect Dis, 2009, 199 (3): 405-413.
13. Patel A, Tran K, Gray M, et al. Evaluation of conserved and variable influenza antigens for immunization against different isolates of H5N1 viruses. Vaccine, 2009, 27(23): 3083-3089.
14. Brown L E, Kelso A. Prospects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes. Immunol Cell Biol, 2009, 87(4): 300-308.
15. Poon L L, Leung Y H, Nicholls J M, et al. Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice. J Immunol, 2009, 182(5): 3063-3071.
16. Tompkins S M, Zhao Z S, Lo C Y, et al. Matrix protein 2 vaccination and protection against influenza viruses, including subtype H5N1. Emerg Infect Dis, 2007, 13(3): 426-435.
17. Kreijtz J H, Suezer Y, de Mutsert G, et al. Preclinical evaluation of a modified vaccinia virus Ankara (MVA) -based vaccine against influenza A/H5N1 viruses. Vaccine, 2009, 27(45): 6296-6299.
18. Fang Q, Yang L, Zhu W, et al. Host range, growth property, and virulence of the smallpox vaccine: vaccinia virus Tian Tan strain. Virology, 2005, 335(2): 242-251.