HLA-B*1502 allele is associated with a cross-reactivity pattern of cutaneous adverse reactions to antiepileptic drugs

Journal of International Medical Research

Volumn 40, Issue 1, 2012, Pages 377-382

  Wang, J ^a   Zhang, J ^b   Wu, X ^a   Yu, P ^a   Hong, Zhen ^a  

^a The State Key Laboratory of Medical Neurobiology   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Antiepileptic drugs (AEDs); Asian patients; Cross reactivity; Cutaneous adverse drug reactions (cADRs); Epilepsy; Human leucocyte antigen B (HLA B) *1502 allele

Indexed keywords

ANTICONVULSIVE AGENT; ANTIHISTAMINIC AGENT; CARBAMAZEPINE; CORTICOSTEROID; ETIRACETAM; GENOMIC DNA; HLA B ANTIGEN; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; TOPIRAMATE; VALPROIC ACID; HLA B*15:02 ANTIGEN; HLA B15 ANTIGEN; HLA-B*15:02 ANTIGEN;

AGED; ALLELE; ARTICLE; BLISTER; BRAIN ATROPHY; CASE REPORT; CHINESE; COMPLEX PARTIAL SEIZURE; COMPUTER ASSISTED TOMOGRAPHY; DNA EXTRACTION; DRUG CROSS REACTIVITY; DRUG DOSE INCREASE; DRUG ERUPTION; DRUG FEVER; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ELECTROENCEPHALOGRAPHY; EOSINOPHIL COUNT; EPILEPSY; EPILEPTIC DISCHARGE; ERYTHEMA; EYE INFECTION; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HOSPITAL DISCHARGE; HUMAN; JAUNDICE; LABORATORY TEST; LEUKOCYTE COUNT; LEUKOCYTOSIS; MACULOPAPULAR RASH; MOUTH ULCER; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; PRURITUS; SKIN TOXICITY; SORE THROAT; STEVENS JOHNSON SYNDROME; TONIC CLONIC SEIZURE; ADOLESCENT; ADULT; CROSS REACTION; DRUG EFFECT; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MIDDLE AGED; SKIN;

ADOLESCENT; AGED; ALLELES; ANTICONVULSANTS; CROSS REACTIONS; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HLA-B15 ANTIGEN; HUMANS; MIDDLE AGED; SKIN; YOUNG ADULT;

EID: 84863243282     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001204000140     Document Type: Article

References (18)

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