-
2
-
-
0029914194
-
Invasive fibroblast-like synoviocytes in rheumatoid arthritis: Passive responders or transformed aggressors?
-
Firestein GS,. Invasive fibroblast-like synoviocytes in rheumatoid arthritis: passive responders or transformed aggressors? Arthritis Rheum 1996; 39: 1781-90.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 1781-1790
-
-
Firestein, G.S.1
-
3
-
-
0033510414
-
Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis
-
Reece RJ, Canete JD, Parsons WJ, Emery P, Veale DJ,. Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis. Arthritis Rheum 1999; 42: 1481-4.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 1481-1484
-
-
Reece, R.J.1
Canete, J.D.2
Parsons, W.J.3
Emery, P.4
Veale, D.J.5
-
4
-
-
0142187335
-
Angiogenesis as a target in rheumatoid arthritis
-
Koch AE,. Angiogenesis as a target in rheumatoid arthritis. Ann Rheum Dis 2003; 62 Suppl 2: ii60-7.
-
(2003)
Ann Rheum Dis
, vol.62
, Issue.SUPPL. 2
-
-
Koch, A.E.1
-
5
-
-
0347236888
-
Progression of radiologic damage in patients with rheumatoid arthritis in clinical remission
-
Molenaar ET, Voskuyl AE, Dinant HJ, Bezemer PD, Boers M, Dijkmans BA,. Progression of radiologic damage in patients with rheumatoid arthritis in clinical remission. Arthritis Rheum 2004; 50: 36-42.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 36-42
-
-
Molenaar, E.T.1
Voskuyl, A.E.2
Dinant, H.J.3
Bezemer, P.D.4
Boers, M.5
Dijkmans, B.A.6
-
6
-
-
0036839553
-
Bone destruction in arthritis
-
Gravallese EM,. Bone destruction in arthritis. Ann Rheum Dis 2002; 61 Suppl 2: ii84-6.
-
(2002)
Ann Rheum Dis
, vol.61
, Issue.SUPPL. 2
-
-
Gravallese, E.M.1
-
7
-
-
1842505684
-
Joint erosion in rheumatoid arthritis: Interactions between tumour necrosis factor α, interleukin 1, and receptor activator of nuclear factor κb ligand (RANKL) regulate osteoclasts
-
O'Gradaigh D, Ireland D, Bord S, Compston JE,. Joint erosion in rheumatoid arthritis: interactions between tumour necrosis factor α, interleukin 1, and receptor activator of nuclear factor κB ligand (RANKL) regulate osteoclasts. Ann Rheum Dis 2004; 63: 354-9.
-
(2004)
Ann Rheum Dis
, vol.63
, pp. 354-359
-
-
O'Gradaigh, D.1
Ireland, D.2
Bord, S.3
Compston, J.E.4
-
8
-
-
45149127782
-
Osteoimmunology: Interactions of the bone and immune system
-
Lorenzo J, Horowitz M, Choi Y,. Osteoimmunology: interactions of the bone and immune system. Endocr Rev 2008; 29: 403-40.
-
(2008)
Endocr Rev
, vol.29
, pp. 403-440
-
-
Lorenzo, J.1
Horowitz, M.2
Choi, Y.3
-
9
-
-
49149107848
-
Osteoimmunology: Cytokines and the skeletal system
-
Lee SH, Kim TS, Choi Y, Lorenzo J,. Osteoimmunology: cytokines and the skeletal system. BMB Rep 2008; 41: 495-510.
-
(2008)
BMB Rep
, vol.41
, pp. 495-510
-
-
Lee, S.H.1
Kim, T.S.2
Choi, Y.3
Lorenzo, J.4
-
10
-
-
42649134105
-
Interleukin-21: Basic biology and implications for cancer and autoimmunity
-
Spolski R, Leonard WJ,. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu Rev Immunol 2008; 26: 57-79.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 57-79
-
-
Spolski, R.1
Leonard, W.J.2
-
11
-
-
36849036211
-
IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner
-
Wei L, Laurence A, Elias KM, O'Shea JJ,. IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J Biol Chem 2007; 282: 34605-10.
-
(2007)
J Biol Chem
, vol.282
, pp. 34605-34610
-
-
Wei, L.1
Laurence, A.2
Elias, K.M.3
O'Shea, J.J.4
-
12
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva R, Yang XO, Martinez G, Zhang Y, Panopoulos AD, Ma L, et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007; 448: 480-3.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
Zhang, Y.4
Panopoulos, A.D.5
Ma, L.6
-
13
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
Sato K, Suematsu A, Okamoto K, Yamaguchi A, Morishita Y, Kadono Y, et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 2006; 203: 2673-82.
-
(2006)
J Exp Med
, vol.203
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
Yamaguchi, A.4
Morishita, Y.5
Kadono, Y.6
-
14
-
-
34247570854
-
Cells of the synovium in rheumatoid arthritis: T lymphocytes
-
Lundy SK, Sarkar S, Tesmer LA, Fox DA,. Cells of the synovium in rheumatoid arthritis: T lymphocytes. Arthritis Res Ther 2007; 9: 202.
-
(2007)
Arthritis Res Ther
, vol.9
, pp. 202
-
-
Lundy, S.K.1
Sarkar, S.2
Tesmer, L.A.3
Fox, D.A.4
-
15
-
-
47249128991
-
Th17 cells in human disease
-
Tesmer LA, Lundy SK, Sarkar S, Fox DA,. Th17 cells in human disease. Immunol Rev 2008; 223: 87-113.
-
(2008)
Immunol Rev
, vol.223
, pp. 87-113
-
-
Tesmer, L.A.1
Lundy, S.K.2
Sarkar, S.3
Fox, D.A.4
-
16
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397: 315-23.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.Y.1
Yoshida, H.2
Sarosi, I.3
Tan, H.L.4
Timms, E.5
Capparelli, C.6
-
17
-
-
49049103008
-
IL-23 induces receptor activator of NF-κB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model
-
Ju JH, Cho ML, Moon YM, Oh HJ, Park JS, Jhun JY, et al. IL-23 induces receptor activator of NF-κB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model. J Immunol 2008; 181: 1507-18.
-
(2008)
J Immunol
, vol.181
, pp. 1507-1518
-
-
Ju, J.H.1
Cho, M.L.2
Moon, Y.M.3
Oh, H.J.4
Park, J.S.5
Jhun, J.Y.6
-
18
-
-
0036159173
-
Cyclosporine differentially regulates interleukin-10, interleukin-15, and tumor necrosis factor α production by rheumatoid synoviocytes
-
Cho ML, Kim WU, Min SY, Min DJ, Min JK, Lee SH, et al. Cyclosporine differentially regulates interleukin-10, interleukin-15, and tumor necrosis factor α production by rheumatoid synoviocytes. Arthritis Rheum 2002; 46: 42-51.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 42-51
-
-
Cho, M.L.1
Kim, W.U.2
Min, S.Y.3
Min, D.J.4
Min, J.K.5
Lee, S.H.6
-
19
-
-
17444452820
-
Activated human T cells directly induce osteoclastogenesis from human monocytes: Possible role of T cells in bone destruction in rheumatoid arthritis patients
-
Kotake S, Udagawa N, Hakoda M, Mogi M, Yano K, Tsuda E, et al. Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum 2001; 44: 1003-12.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1003-1012
-
-
Kotake, S.1
Udagawa, N.2
Hakoda, M.3
Mogi, M.4
Yano, K.5
Tsuda, E.6
-
20
-
-
0034121039
-
Involvement of receptor activator of nuclear factor κb ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis
-
Takayanagi H, Iizuka H, Juji T, Nakagawa T, Yamamoto A, Miyazaki T, et al. Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum 2000; 43: 259-69.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 259-269
-
-
Takayanagi, H.1
Iizuka, H.2
Juji, T.3
Nakagawa, T.4
Yamamoto, A.5
Miyazaki, T.6
-
21
-
-
34247881945
-
Human rheumatoid synovial fibroblasts promote osteoclastogenic activity by activating RANKL via TLR-2 and TLR-4 activation
-
Kim KW, Cho ML, Lee SH, Oh HJ, Kang CM, Ju JH, et al. Human rheumatoid synovial fibroblasts promote osteoclastogenic activity by activating RANKL via TLR-2 and TLR-4 activation. Immunol Lett 2007; 110: 54-64.
-
(2007)
Immunol Lett
, vol.110
, pp. 54-64
-
-
Kim, K.W.1
Cho, M.L.2
Lee, S.H.3
Oh, H.J.4
Kang, C.M.5
Ju, J.H.6
-
22
-
-
2342491493
-
Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis
-
Jungel A, Distler JH, Kurowska-Stolarska M, Seemayer CA, Seibl R, Forster A, et al. Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis. Arthritis Rheum 2004; 50: 1468-76.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1468-1476
-
-
Jungel, A.1
Distler, J.H.2
Kurowska-Stolarska, M.3
Seemayer, C.A.4
Seibl, R.5
Forster, A.6
-
23
-
-
0037159687
-
A critical role for IL-21 in regulating immunoglobulin production
-
Ozaki K, Spolski R, Feng CG, Qi CF, Cheng J, Sher A, et al. A critical role for IL-21 in regulating immunoglobulin production. Science 2002; 298: 1630-4.
-
(2002)
Science
, vol.298
, pp. 1630-1634
-
-
Ozaki, K.1
Spolski, R.2
Feng, C.G.3
Qi, C.F.4
Cheng, J.5
Sher, A.6
-
24
-
-
56749183893
-
Interleukin 21 as a target of intervention in autoimmune disease
-
Ettinger R, Kuchen S, Lipsky PE,. Interleukin 21 as a target of intervention in autoimmune disease. Ann Rheum Dis 2008; 67 Suppl 3: iii83-6.
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.SUPPL. 3
-
-
Ettinger, R.1
Kuchen, S.2
Lipsky, P.E.3
-
25
-
-
77149122105
-
IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
-
Linterman MA, Beaton L, Yu D, Ramiscal RR, Srivastava M, Hogan JJ, et al. IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses. J Exp Med 2007: 353-63.
-
(2007)
J Exp Med
, pp. 353-363
-
-
Linterman, M.A.1
Beaton, L.2
Yu, D.3
Ramiscal, R.R.4
Srivastava, M.5
Hogan, J.J.6
-
26
-
-
33947215987
-
IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression
-
Herber D, Brown TP, Liang S, Young DA, Collins M, Dunussi-Joannopoulos K,. IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression. J Immunol 2007; 178: 3822-30.
-
(2007)
J Immunol
, vol.178
, pp. 3822-3830
-
-
Herber, D.1
Brown, T.P.2
Liang, S.3
Young, D.A.4
Collins, M.5
Dunussi-Joannopoulos, K.6
-
27
-
-
35748930247
-
Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus
-
Bubier JA, Bennett SM, Sproule TJ, Lyons BL, Olland S, Young DA, et al. Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus. Ann N Y Acad Sci 2007; 1110: 590-601.
-
(2007)
Ann N y Acad Sci
, vol.1110
, pp. 590-601
-
-
Bubier, J.A.1
Bennett, S.M.2
Sproule, T.J.3
Lyons, B.L.4
Olland, S.5
Young, D.A.6
-
28
-
-
60849107595
-
A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
-
Bubier JA, Sproule TJ, Foreman O, Spolski R, Shaffer DJ, Morse HC 3rd, et al. A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice. Proc Natl Acad Sci U S A 2009; 106: 1518-23.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1518-1523
-
-
Bubier, J.A.1
Sproule, T.J.2
Foreman, O.3
Spolski, R.4
Shaffer, D.J.5
Morse III, H.C.6
-
29
-
-
33749552196
-
Interleukin-21 induces T-cell activation and proinflammatory cytokine secretion in rheumatoid arthritis
-
Li J, Shen W, Kong K, Liu Z,. Interleukin-21 induces T-cell activation and proinflammatory cytokine secretion in rheumatoid arthritis. Scand J Immunol 2006; 64: 515-22.
-
(2006)
Scand J Immunol
, vol.64
, pp. 515-522
-
-
Li, J.1
Shen, W.2
Kong, K.3
Liu, Z.4
-
30
-
-
34247257447
-
Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis
-
Young DA, Hegen M, Ma HL, Whitters MJ, Albert LM, Lowe L, et al. Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis. Arthritis Rheum 2007; 56: 1152-63.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1152-1163
-
-
Young, D.A.1
Hegen, M.2
Ma, H.L.3
Whitters, M.J.4
Albert, L.M.5
Lowe, L.6
-
31
-
-
65249180981
-
A positive feedback loop of IL-21 signaling provoked by homeostatic CD4+CD25- T cell expansion is essential for the development of arthritis in autoimmune K/BxN mice
-
Jang E, Cho SH, Park H, Paik DJ, Kim JM, Youn J,. A positive feedback loop of IL-21 signaling provoked by homeostatic CD4+CD25- T cell expansion is essential for the development of arthritis in autoimmune K/BxN mice. J Immunol 2009; 182: 4649-56.
-
(2009)
J Immunol
, vol.182
, pp. 4649-4656
-
-
Jang, E.1
Cho, S.H.2
Park, H.3
Paik, D.J.4
Kim, J.M.5
Youn, J.6
-
32
-
-
59849091674
-
Serum IL-21 level in patients with primary Sjogren's syndrome and clinical significance of IL-21
-
In Chinese.
-
Yuan SL, Jiang L, Zhang XL, Li SF, Duan HM, Wang XF,. Serum IL-21 level in patients with primary Sjogren's syndrome and clinical significance of IL-21. Chinese J Cellular and Molecular Immunology 2007; 23: 124-6. In Chinese.
-
(2007)
Chinese J Cellular and Molecular Immunology
, vol.23
, pp. 124-126
-
-
Yuan, S.L.1
Jiang, L.2
Zhang, X.L.3
Li, S.F.4
Duan, H.M.5
Wang, X.F.6
-
33
-
-
46349111508
-
Interleukin-6 inhibits receptor activator of nuclear factor κb ligand-induced osteoclastogenesis by diverting cells into the macrophage lineage: Key role of Serine727 phosphorylation of signal transducer and activator of transcription 3
-
Duplomb L, Baud'huin M, Charrier C, Berreur M, Trichet V, Blanchard F, et al. Interleukin-6 inhibits receptor activator of nuclear factor κB ligand-induced osteoclastogenesis by diverting cells into the macrophage lineage: key role of Serine727 phosphorylation of signal transducer and activator of transcription 3. Endocrinology 2008; 149: 3688-97.
-
(2008)
Endocrinology
, vol.149
, pp. 3688-3697
-
-
Duplomb, L.1
Baud'Huin, M.2
Charrier, C.3
Berreur, M.4
Trichet, V.5
Blanchard, F.6
-
34
-
-
0033680153
-
The course of radiologic damage during the first six years of rheumatoid arthritis
-
Hulsmans HM, Jacobs JW, van der Heijde DM, van Albada-Kuipers GA, Schenk Y, Bijlsma JW,. The course of radiologic damage during the first six years of rheumatoid arthritis. Arthritis Rheum 2000; 43: 1927-40.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 1927-1940
-
-
Hulsmans, H.M.1
Jacobs, J.W.2
Van Der Heijde, D.M.3
Van Albada-Kuipers, G.A.4
Schenk, Y.5
Bijlsma, J.W.6
-
35
-
-
0037629038
-
Course of radiographic damage over 10 years in a cohort with early rheumatoid arthritis
-
Lindqvist E, Jonsson K, Saxne T, Eberhardt K,. Course of radiographic damage over 10 years in a cohort with early rheumatoid arthritis. Ann Rheum Dis 2003; 62: 611-6.
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 611-616
-
-
Lindqvist, E.1
Jonsson, K.2
Saxne, T.3
Eberhardt, K.4
-
36
-
-
0036892108
-
Ten year outcome in a cohort of patients with early rheumatoid arthritis: Health status, disease process, and damage
-
Lindqvist E, Saxne T, Geborek P, Eberhardt K,. Ten year outcome in a cohort of patients with early rheumatoid arthritis: health status, disease process, and damage. Ann Rheum Dis 2002; 61: 1055-9.
-
(2002)
Ann Rheum Dis
, vol.61
, pp. 1055-1059
-
-
Lindqvist, E.1
Saxne, T.2
Geborek, P.3
Eberhardt, K.4
-
37
-
-
0034735842
-
Infliximab and methotrexate in the treatment of rheumatoid arthritis
-
for the Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group.
-
Lipsky PE, van der Heijde DM, St Clair EW, Furst DE, Breedveld FC, Kalden JR, et al, for the Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. Infliximab and methotrexate in the treatment of rheumatoid arthritis. N Engl J Med 2000; 343: 1594-602.
-
(2000)
N Engl J Med
, vol.343
, pp. 1594-1602
-
-
Lipsky, P.E.1
Van Der Heijde, D.M.2
St Clair, E.W.3
Furst, D.E.4
Breedveld, F.C.5
Kalden, J.R.6
-
38
-
-
10744223002
-
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: Double-blind randomised controlled trial
-
Klareskog L, van der Heijde D, de Jager JP, Gough A, Kalden J, Malaise M, et al. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial. Lancet 2004; 363: 675-81.
-
(2004)
Lancet
, vol.363
, pp. 675-681
-
-
Klareskog, L.1
Van Der Heijde, D.2
De Jager, J.P.3
Gough, A.4
Kalden, J.5
Malaise, M.6
-
39
-
-
31044442965
-
The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment
-
Breedveld FC, Weisman MH, Kavanaugh AF, Cohen SB, Pavelka K, van Vollenhoven R, et al. The PREMIER study: a multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. Arthritis Rheum 2006; 54: 26-37.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 26-37
-
-
Breedveld, F.C.1
Weisman, M.H.2
Kavanaugh, A.F.3
Cohen, S.B.4
Pavelka, K.5
Van Vollenhoven, R.6
|