Targeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice

Infection and Immunity

Volumn 80, Issue 3, 2012, Pages 1156-1165

  Pszenny, Viviana ^a,e   Davis, Paul H ^a,f   Zhou, Xing W ^b   Hunter, Christopher A ^c   Carruthers, Vern B ^d   Roos, David S ^a  

^a Department of Pathobiology ^*  (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^f UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; GENOMIC DNA; LECTIN; SERINE PROTEINASE INHIBITOR; TOXOPLASMA GONDII SERINE PROTEASE INHIBITOR 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRADYZOITE; CELL DIFFERENTIATION; CELL VACUOLE; CYTOPLASM; DNA FLANKING REGION; GENE DELETION; GENE LOCUS; GENETIC COMPLEMENTATION; GENETIC TRANSCRIPTION; HOST CELL; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER; MOUSE; NONHUMAN; PARASITE LOAD; PARASITE VIRULENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; RNA SPLICING; SPLEEN; TACHYZOITE; TOXOPLASMA GONDII;

ANIMALS; FEMALE; GENE KNOCKOUT TECHNIQUES; GENETIC COMPLEMENTATION TEST; LIVER; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; SEQUENCE ANALYSIS, DNA; SERINE PROTEINASE INHIBITORS; SPLEEN; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; VIRULENCE FACTORS;

EID: 84863229522     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.06167-11     Document Type: Article

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