Major constituents and cytotoxic effects of Ajuga chamaecistus ssp. tomentella

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 67 C, Issue 5-6, 2012, Pages 275-281

  Sadati, Nargess ^a   Jenett Siems, Kristina ^b   Siems, Karsten ^c   Ardekani, Mohammad Reza Shams ^a   Hadjiakhoondi, Abbas ^a   Akbarzadeh, Tahmineh ^a   Ostad, Seyed Nasser ^d   Khanavi, Mahnaz ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c ANALYTICON DISCOVERY GMBH   (Germany)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Ajuga chamaecistus ssp. tomentella; Cytotoxic Effect; Melilotoside

Indexed keywords

AJUGA; TOMENTELLA;

EID: 84863220419     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2012-5-606     Document Type: Article

References (36)

1. Akbay P., Gertsch J., Calis I., Heilmann J., Zerbe O., and Sticker O. (2002), Novel antileukemic sterol glycosides from Ajuga salicifolia. Helv. Chim. Acta 85, 1930-1942.
2. Akbay P., Calis I., Heimann J., and Sticher O. (2003), Ionon, iridoid and phenylethanoid glycosides from Ajuga salicifolia. Z. Naturforsch. 58c, 177-180.
3. Basaran A. A., Calis I., Anklin C., Nishibe S., and Sticher O. (1988), Lavandulifolioside: A new phenylpropanoid glycoside from Stachys lavandulifolia. Helv. Chim. Acta 71, 1483-1489.
4. Cai Y.-J., Dai J.-Q., Fang J.-G., Ma L.-P., Hou L.-F., Yang L., and Liu Z.-L. (2002), Antioxidative and free radical scavenging effects of ecdysteroids from Serratula strangulate. Can. J. Physiol. Pharmacol. 80, 1187-1194.
5. Calis I., Ersoz T., Tasdemir D., and Ruedi P. (1992), Two phenylpropanoid glycosides from Leonurus glaucescens. Phytochemistry 31, 357-359.
6. Calzada F., Velazquez C., Cedillo-Rivera R., and Esquivel B. (2003), Antiprotozoal activity of the constituents of Teloxys graveolens. Phytother. Res. 17, 731-732.
7. Castro A., Coll J., Tandron Y. A., Pant A. K., and Mathela C. (2008), Phytoecdysteroids from Ajuga macrosperma var. brevifl ora roots. J. Nat. Prod. 71, 1294-1296.
8. Coll J. (2002), NMR shift data of neo-clerodane diterpenes from the genus Ajuga. Phytochem. Anal. 13, 372-380.
9. Dinan L. (2009), Phytoecdysteroids: what use are they? Arch. Insect Biochem. Physiol. 72, 126-141.
10. Ferreira F. P. and Rodrigues de Oliveira D. C. (2010), New constituents from Mikania laevigata Shultz Bip. ex Baker. Tetrahedron Lett. 51, 6856-6859.
11. Gautam R., Jachak S. M., and Saklani A. (2011), Anti-infl ammatory effect of Ajuga bracteosa Wall ex Benth. mediated through cyclooxygenase (COX) inhibition. J. Ethnopharmacol. 133, 928-930.
12. 2+fl ux leading to Akt activation and increased protein synthesis in skeletal muscle cells. Steroids 75, 632-637.
13. Hamden K., Ayadi K., Jamoussi K., Masmoudi H., and Eifeki A. (2008), Therapeutic effect of phytoecdysteroids rich extract from Ajuga iva on alloxan induced diabetic rats liver, kidney and pancreas. BioFactors 33, 165-175.
14. Hilaly J. and Lyoussi B. (2002), Hypoglycemic effect of lyophilized aqueous extract of Ajuga iva in normal and streptozotocin diabetic rats. J. Ethnopharmacol. 80, 109-113.
15. 28steroid. Tetrahedron Lett., 3883-3886.
16. Imai S., Murata E., Fujioka S., Matsuoka T., Koreeda M., and Nakanishi K. (1970), Ajugalactone, an insect moulting inhibitor as tested by the chio dipping method. J. Am. Chem. Soc. 92, 7512-7513.
17. Jimenez C. and Riguera R. (1994), Phenylethanoid glycosides in plants: structure and biological activity. Nat. Prod. Rep. 11, 591-606.
18. Kahnt G. (1962), Isolierung des trans-und cis-o-Oxyzimtsäureglucosids aus Steinkleeblättern (Melilotus albus) und Umwandlung der trans-Form in die isomere Verbindung in vivo und in vitro durch Sonnenlicht. Naturwissenschaften 49, 207-208.
19. Khanavi M., Nabavi M., Sadati N., Shams Ardekani M. R., Sohrabipour J., Nabavi S. M. B., Ghaeli P., and Ostad S. N. (2010), Cytotoxic activity of some marine brown algae against cancer cell lines. Biol. Res. 43, 31-37.
20. Kuria K. A. M., Coster S., Muriuki G., Masengo W., Kibwage I., Hoogmartens J., and Laekeman G. M. (2001), Antimalarial activity of Ajuga remota Benth (Labiatae) and Caesalpinia volkensii Harms (Caesalpiniaceae): in vitro confi rmation of ethnopharmacological use. J. Ethnopharmacol. 74, 141-148.
21. Kutepova T. A., Syrov V. N., Khushbaktova Z. A., and Saatov Z. (2001), Hypoglycemic activity of the total ecdysteroid extract from Ajuga turkestanica. Pharm. Chem. J. (Translation of Khimiko-Farmatsevticheskii Zhurnal) 35, 608-609.
22. Manguro L. O. A., Ogur J. A., Okora D. M., Wagal S. O., and Lemen P. (2007), Further fl avonol and iridoid glycosides from Ajuga remota. J. Asian Nat. Prod. Res. 9, 617-629.
23. Miao J., Wang W., Yao S., Navaratnam S., and Parsons B. J. (2003), Antioxidative properties of martynoside: pulse radiolysis and laser photolysis study. Free Radical Res. 37, 829-833.
24. Milkowska-Leyck K., Filipek B., and Strezelecka H. (2002), Pharmacological effects of lavandulifolioside from Leonurus cardiac. J. Ethnopharmacol. 80, 85-90.
25. Mozaffarian V. (2007), A Dictionary of Iranian Plant Names. Farhang moaser, Tehran, pp. 21-22.
26. Naghibi F., Mosaddegh M., Mohammadi Motamed S., and Ghorbani A. (2005), Labiatae family in folk medicine in Iran: from ethnobotany to pharmacology. Iran. J. Pharm. Res. 2, 63-79.
27. Ono Y., Fukaya Y., Imai S., and Yamakuni T. (2008), Benefi cial effects of Ajuga decumbens on osteoporosis and arthritis. Biol. Pharm. Bull. 31, 1199-1204.
28. Papoutsi Z., Kassi E., Mitakou S., Aligiannis N., Tsiapara A., Chrousos G. P., and Moutsatsou P. (2006), Acteoside and martynoside exhibit estrogenic/ antiestrogenic properties. J. Steroid Biochem. Mol. Biol. 98, 63-71.
29. Ramazanov N. Sh. (2005), Phytoecdysteroids and other biologically active compounds from plants of genus Ajuga. Chem. Nat. Compd. 41, 361-369.
30. Sadati N., Ostad S. N., Karimian Z., Shams Ardekani M. R., Akbarzadeh T., Hadjiakhoondi A., and Khanavi M. (2012), Phytochemical study and in vitro cytotoxic effect of Ajuga chamaecistus ssp. tomentella. Asian J. Chem. 24, 2871-2874.
31. Sasaki H., Taguchi H., Endo T., Yosioka I., Higashiyama K., and Otomasu H. (1978), The glycosides of Martynia louisiana Mill. A new phenylpropanoid glycoside, martynoside. Chem. Pharm. Bull. 26, 2111-2121.
32. Takaishi K. (1968), Studies on the coumarin components in the leaves of cherry-tree. Yakugaku Zasshi 88, 1467-1471.
33. Wessner H., Champion B., Girault J.-P., Saidi B., and Lafont R. (1992), Ecdysteroids from Ajuga iva. Phytochemistry 31, 3785-3788.
34. Vanyolos A., Simon A., Toth G., Polgar L., Kele Z., Ilku A., Matyus P., and Bathori M. (2009), C-29 Ecdysteroids from Ajuga reptans. J. Nat. Prod. 72, 929-932.
35. Yang L., Han H., Nakamura N., Hattori M., Wang Z., and Xu L. (2007a), Bio-guided isolation of antioxidants from the stems of Dendrobium auranticum var. denneanum. Phytother. Res. 21, 696-698.
36. Yang L., Nakamura N., Hattori M., Wang Z., Bligh S. W. A., and Xu L. (2007b), High-performance liquid chromatography-diode array detection/electrospray ionization mass spectrometry for simultaneous analysis of cis-, trans-and dihydro-2-glucosyloxycinnamic acid derivatives from Dendrobium medicinal plants. Rapid Commun. Mass Spectrom. 21, 1833-1840.