Primary graft dysfunction after living donor liver transplantation is characterized by delayed functional hyperbilirubinemia

American Journal of Transplantation

Volumn 12, Issue 7, 2012, Pages 1886-1897

  Ikegami, Toru ^a   Shirabe, K ^a   Yoshizumi, T ^a   Aishima, S ^a   Taketomi, Y A ^a   Soejima, Y ^a   Uchiyama, H ^a   Kayashima, H ^a   Toshima, T ^a   Maehara, Y ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Donor age; Graft dysfunction; Hyperbilirubinemia; Living donor liver transplantation; Small for size

Indexed keywords

BILIRUBIN;

ACUTE LIVER FAILURE; ADULT; AGED; ARTICLE; BLOOD CLOTTING DISORDER; CHOLESTASIS; CONTROLLED STUDY; DELAYED FUNCTIONAL HYPERBILIRUBINEMIA; FEMALE; GRAFT SURVIVAL; HUMAN; HUMAN TISSUE; HYPERBILIRUBINEMIA; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; LIVING DONOR; LIVING DONOR LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIMARY GRAFT DYSFUNCTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ADULT; FEMALE; HUMANS; HYPERBILIRUBINEMIA; LIVER TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; SENSITIVITY AND SPECIFICITY; TISSUE DONORS;

EID: 84863205911     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2012.04052.x     Document Type: Article

References (33)

1. Ploeg RJ, D'Alessandro AM, Knechtle SJ, et al. Risk factors for primary dysfunction after liver transplantation-a multivariate analysis. Transplantation 1993; 55: 807-813. (Pubitemid 23122053)
2. GlanemannM, Langrehr JM, Stange BJ, et al. Clinical implications of hepatic preservation injury after adult liver transplantation. Am J Transplant 2003; 3: 1003-1009. (Pubitemid 36917548)
3. Uemura T, Randall HB, Sanchez EQ, et al. Liver retransplantation for primary nonfunction: Analysis of a 20-year single-center experience. Liver Transpl 2007; 13: 227-233. (Pubitemid 46351648)
4. Freise CE, Gillespie BW, Koffron AJ, et al. Recipient morbidity after living and deceased donor liver transplantation: Findings from the A2ALL Retrospective Cohort Study. Am J Transplant 2008; 8: 2569-2579.
5. Bourdeaux C, Darwish A, Jamart J, et al. Living-related versus deceased donor pediatric liver transplantation: Amultivariate analysis of technical and immunological complications in 235 recipients. Am J Transplant 2007; 7: 440-447. (Pubitemid 46096338)
6. Marcos A, Ham JM, Fisher RA, et al. Surgical management of anatomical variations of the right lobe in living donor liver transplantation. Ann Surg 2000; 231: 824-831. (Pubitemid 30350240)
7. Morioka D, Egawa H, KasaharaM, et al. Outcomes of adult-to-adult living donor liver transplantation: A single institution's experience with 335 consecutive cases. Ann Surg 2007; 245: 315-325. (Pubitemid 46148492)
8. Dahm F, Georgiev P, Clavien PA. Small-for-size syndrome after partial liver transplantation: Definition, mechanisms of disease and clinical implications. Am J Transplant 2005; 5: 2605-2610.
9. Kiuchi T, Tanaka K, Ito T, et al. Small-for-size graft in living donor liver transplantation: How far should we go? Liver Transpl 2003; 9: S29-S35. (Pubitemid 37098863)
10. Kasahara M, Takada Y, Fujimoto Y, et al. Impact of right lobe with middle hepatic vein graft in living-donor liver transplantation. Am J Transplant 2005; 5: 1339-1346. (Pubitemid 40839423)
11. Moon JI, Kwon CH, Joh JW, et al. Safety of small-for-size grafts in adult-to-adult living donor liver transplantation using the right lobe. Liver Transpl 2010; 16: 864-869.
12. Yi NJ, Suh KS, Lee HW, et al. Improved outcome of adult recipients with a high model for end-stage liver disease score and a small-for-size graft. Liver Transpl 2009; 15: 496-503.
13. Chan SC, Lo CM, Ng KK, et al. Alleviating the burden of small-for-size graft in right liver living donor liver transplantation through accumulation of experience. Am J Transplant 2010; 10: 859-867.
14. Hill MJ, Hughes M, Jie T, et al. Graft weight/recipient weight ratio: How well does it predict outcome after partial liver transplants? Liver Transpl 2009; 15: 1056-1062.
15. Kiuchi T, Onishi Y, Nakamura T. Small-for-size graft: not defined solely by being small for size. Liver Transpl 2010; 16: 815-817.
16. Soejima Y, Taketomi A, Yoshizumi T, et al. Feasibility of left lobe living donor liver transplantation between adults: an 8-year, single-center experience of 107 cases. Am J Transplant 2006; 6: 1004-1011. (Pubitemid 44356651)
17. Yonemura Y, Taketomi A, Soejima Y, et al. Validity of preoperative volumetric analysis of congestion volume in living donor liver transplantation using three-dimensional computed tomography. Liver Transpl 2005; 11: 1556-1562. (Pubitemid 43072633)
18. Taketomi A, Morita K, Toshima T, et al. Living donor hepatectomies with procedures to prevent biliary complications. J Am Coll Surg 2010; 211: 456-464.
19. Ikegami T, Soejima Y, Taketomi A, et al. Explanted portal vein grafts for middle hepatic vein tributaries in living-donor liver transplantation. Transplantation 2007; 84: 836-841. (Pubitemid 351338943)
20. Marubashi S, Dono K, Nagano H, et al. Postoperative hyperbilirubinemia and graft outcome in living donor liver transplantation. Liver Transpl 2007; 13: 1538-1544. (Pubitemid 350168194)
21. Emond JC, Renz JF, Ferrell LD, et al. Functional analysis of grafts from living donors. Implications for the treatment of older recipients. Ann Surg 1996; 224: 544-552.
22. Fusai G, Dhaliwal P, Rolando N, et al. Incidence and risk factors for the development of prolonged and severe intrahepatic cholestasis after liver transplantation. Liver Transpl 2006; 12: 1626-1633. (Pubitemid 44742541)
23. Balzan S, Belghiti J, Farges O, et al. The "50-50 criteria" on postoperative day 5: An accurate predictor of liver failure and death after hepatectomy. Ann Surg 2005; 242: 824-828.
24. Gaffey MJ, Boyd JC, Traweek ST, et al. Predictive value of intraoperative biopsies and liver function tests for preservation injury in orthotopic liver transplantation. Hepatology 1997; 25: 184-189. (Pubitemid 27015008)
25. Khettry U, Backer A, Ayata G, et al. Centrilobular histopathologic changes in liver transplant biopsies. Hum Pathol 2002; 33: 270-276. (Pubitemid 34461459)
26. Demetris AJ, Kelly DM, Eghtesad B, et al. Pathophysiologic observations and histopathologic recognition of the portal hyperperfusion or small-for-size syndrome. Am J Surg Pathol 2006; 30: 986-993. (Pubitemid 44264948)
27. Ng IO, Burroughs AK, Rolles K, et al. Hepatocellular ballooning after liver transplantation: A light and electronmicroscopic study with clinicopathological correlation. Histopathology 1991; 18: 323-330.
28. Kawasaki S, Makuuchi M, Matsunami H, et al. Living related liver transplantation in adults. Ann Surg 1998; 227: 269-274. (Pubitemid 28087921)
29. Nishizaki T, Ikegami T, Hiroshige S, et al. Small graft for living donor liver transplantation. Ann Surg 2001; 233: 575-580. (Pubitemid 32234957)
30. Yoshizumi T, Taketomi A, Uchiyama H, et al. Graft size, donor age, and patient status are the indicators of early graft function after living donor liver transplantation. Liver Transpl 2008; 14: 1007-1013. (Pubitemid 352003900)
31. Ikegami T, Toshima T, Takeishi K, et al. Bloodless splenectomy during liver transplantation for terminal liver diseases with portal hypertension. J Am Coll Surg 2009; 208: e1-e4.
32. ShimadaM, Ijichi H, Yonemura Y, et al. The impact of splenectomy or splenic artery ligation on the outcome of a living donor adult liver transplantation using a left lobe graft. Hepatogastroenterology 2004; 51: 625-629. (Pubitemid 38590926)
33. Ikegami T, Soejima Y, Taketomi A, et al. One orifice vein reconstruction in left liver plus caudate lobe grafts. Transplantation 2007; 84: 1065. (Pubitemid 350287391)