Atheroma plaque, metabolic syndrome and inflammation in patients with psoriasis

European Journal of Dermatology

Volumn 22, Issue 3, 2012, Pages 337-344

  Arias Santiago, Salvador ^a,b,c   Orgaz Molina, Jacinto ^a   Castellote Caballero, Luisa ^a   Arrabal Polo, Miguel Ángel ^c   Garcia Rodrigueź, Sonia ^a   Perandrés López, Rubén ^d   Ruiz, José Carlos ^a   Naranjo Sintes, Ramón ^a   Zubiaur, Mercedes ^d   Sancho, Jaime ^d   Buendia Eisman, Agustín ^b  

^a HOSPITAL UNIVERSITARIO SAN CECILIO   (Spain)

^b Baza General Hospital   (Spain)

^c UNIVERSITY OF GRANADA   (Spain)

^d INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

Author keywords

Atherosclerosis; Cardiovascular risk factors; Comorbidity; Metabolic syndrome; Psoriasis

Indexed keywords

ALDOSTERONE; C REACTIVE PROTEIN; D DIMER; FIBRINOGEN; FOLIC ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOMOCYSTEINE; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ABDOMINAL OBESITY; ADULT; ALCOHOL CONSUMPTION; ALDOSTERONE BLOOD LEVEL; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CAROTID ATHEROSCLEROSIS; CASE CONTROL STUDY; CHOLESTEROL BLOOD LEVEL; COMORBIDITY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DISEASE DURATION; DISEASE SEVERITY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INFLAMMATION; INSULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PROTEIN BLOOD LEVEL; PSORIASIS; RISK ASSESSMENT; SEDENTARY LIFESTYLE; SEX DIFFERENCE; SMOKING HABIT; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE;

ACUTE-PHASE PROTEINS; ADULT; CAROTID ARTERY DISEASES; CASE-CONTROL STUDIES; COMORBIDITY; FEMALE; HUMANS; HYPERHOMOCYSTEINEMIA; HYPERINSULINISM; INFLAMMATION; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PLAQUE, ATHEROSCLEROTIC; PREVALENCE; PSORIASIS; RISK ASSESSMENT; ULTRASONOGRAPHY, DOPPLER;

EID: 84863195930     PISSN: 11671122     EISSN: 19524013     Source Type: Journal    
DOI: 10.1684/ejd.2012.1714     Document Type: Article

References (36)

1. Neimann AL, Shin DB, Wang X, et al. Prevalence of cardiovascular risk factors in patients with psoriasis. J Am Acad Dermatol. 2006; 55:829-835.
2. Sommer DM, Jenisch S, Suchan M, et al. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res 2006; 298:321-328.
3. Hansson GK, Libby P. The immune response in atherosclerosis:a double- edge sword. Nat Rev Immunol 2006; 6:508-519.
4. Kremers H M, McEvoy MT, Dann FJ et al. Heart disease in psoriasis. J Am Acad Dermatol 2007; 57:347-354.
5. Gottlieb AB, Dann F. Comorbidities in patients with psoriasis. Am J Med 2009;122:1150.e1-e9.
6. Shelling ML, Federman DG, Prodanovich S, Kirsner RS. Psoriasis and vascular disease:an unsolved mystery. Am J Med 2008; 121:360-365.
7. Balci DD, Balci A, Karazincir S, et al. Increased carotid artery intima-media thickness and impaired endothelial function in psoriasis. J Eur Acad Dermatol Venereol 2009; 23:1-6.
8. El-Mongy S, Fathy H, Abdelaziz A, et al. Subclinical atherosclerosis in patients with chronic psoriasis:a potential association. J Eur Acad Dermatol Venereol 2010;24(6):661-666.
9. Roman MJ, Shanker BA, Davis A et al. Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus. N Engl J Med 2003; 349:2399-2406.
10. Johnsen SH, Mathiesen EB, Joakimsen O, et al. Carotid atherosclerosis is a stronger predictor of myocardial infarction in women than in men:a 6- year follow-up study of 6226 persons;the Tromsø study. Stroke 2007; 38:2873-2880.
11. Gisondi P, Tessari G, Conti A, et al. Prevalence of metabolic syndrome in patients with psoriasis:a hospital-based case-control study. Br J Dermatol 2007; 157:68-73.
12. Adult Treatment Panel III. Executive summary on the third report of the national cholesterol education program (NECP):expert panel on detection, evaluation and treatment of high blood cholesterol in adults. JAMA 2001; 285:2486-2497.
13. Shapiro J, Cohen AD, Weitzman D, Tal R, David M. Psoriasis and cardiovascular risk factors:A case-control study on inpatients comparing psoriasis to dermatitis. J Am Acad Dermatol. 2011; 66(2):252-258.
14. Icen M, Crowson CS, McEvoy MT, Gabriel SE, Maradit Kremers H. Potential misclassification of patients with psoriasis in electronic databases. J Am Acad Dermatol 2008; 59:981-985.
15. Sommer DM, Jenisch S, Suchan M, Christophers E, Weichenthal M. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res 2006; 298:321-328.
16. Martínez Candela J, Franch Nadal J, Romero Ortiz J, et al. Predictive capacity of the diagnostic criteria of metabolic syndrome on the insulin-resistance and the coronary risk. Med Clin (Barc) 2007; 129:601-606.
17. Assmann G, Schulte H, Seedorf U.Cardiovascular risk assessment in the metabolic syndrome:results from the Prospective Cardiovascular Munster (PROCAM) Study. Int J Obes (Lond) 2008; 32 Suppl 2: S11-S16.
18. Kimball AB, Guerin A, Latremouille-Viau D, et al. Coronary heart disease and stroke risk in patients with psoriasis:retrospective analysis. Am J Med 2010;123:350-357.
19. Mallbris L, Granath F, Hamsten A, Stahle M. Psoriasis is associated with lipid abnormalities at the onset of skin disease. J Am Acad Dermatol 2006; 54:614-621.
20. Kimball AB, Guerin A, Latremouille-Viau D, et al. Coronary heart disease and stroke risk in patients with psoriasis:retrospective analysis. Am J Med 2010; 123:350-357.
21. Mehta NN, Yu Y, Pinnelas R, Krishnamoorthy P, et al. Attributable risk estimate of severe psoriasis on major cardiovascular events. Am J Med. 2011; 124:775.e1-e6.
22. Kimhi O, Caspi D, Bornstein NM et al. Prevalence and risk factors of atherosclerosis in patients with psoriatic arthritis. Semin Arthritis Rheum 2007; 36:203-209.
23. Späh F. Inflammation in atherosclerosis and psoriasis:common pathogenic mechanisms and the potential for an integrated treatment approach. Br J Dermatol 2008; 159(Suppl. 2):10-17.
24. Briet M, Schiffrin EL. The role of aldosterone in the metabolic syndrome. Curr Hypertens Rep 2011; 13:163-172.
25. Arias-Santiago S, Gutiérrez-Salmerón MT, Castellote-Caballero L, et al. Androgenetic alopecia and cardiovascular risk factors in men and women:a comparative study. J Am Acad Dermatol 2010;63:420-429.
26. Arias-Santiago S, Gutiérrez-Salmerón MT, Buendía-Eisman A, Girón-Prieto MS, Naranjo-Sintes R. Hypertension and aldosterone levels in women with early-onset androgenetic alopecia. Br J Dermatol 2010; 162:786-789.
27. Arias-Santiago S, Gutiérrez-Salmerón MT, Castellote-Caballero L, Naranjo-Sintes R. Elevated aldosterone levels in patients with andro-genetic alopecia. Br J Dermatol 2009; 161:1196-1198.
28. Arias-Santiago S, Gutiérrez-Salmerón MT, Buendía-Eisman A, Girón-Prieto MS, Naranjo-Sintes R. Sex hormone-binding globulin and risk of hyperglycemia in patients with androgenetic alopecia. J Am Acad Dermatol 2011; 65:48-53.
29. Kazemi MB, Eshraghian K, Omrani GR et al. Homocysteine level and coronary artery disease. Angiology 2006; 57:9-14.
30. Malerba M, Gisondi P, Radaeli A, Sala R, Calzavara Pinton PG, Girolomoni G. Plasma homocysteine and folate levels in patients with chronic plaque psoriasis. Br J Dermatol 2006; 155:1165-1169.
31. Refsum H, Helland S, Ueland PM. Fasting plasma homocysteine as a sensitive parameter of antifolate effect:a study of psoriasis patients receiving low-dose methotrexate treatment. Clin Pharmacol Ther 1989; 46:510-520.
32. Cakmak SK, Gül U, Kiliç C, Gönül M, Soylu S, Kiliç A. Homo-cysteine, vitamin B12 and folic acid levels in psoriasis patients. J Eur Acad Dermatol Venereol 2009; 23:300-303.
33. Brazzelli V, Grasso V, Fornara L, et al. Homocysteine, vitamin B12 and folic acid levels in psoriatic patients and correlation with disease severity. Int J Immunopathol Pharmacol 2010; 23:911-916.
34. Hermann W. The importance of hyperhomocysteinemia as a risk factor for diseases:an overview. Clin Chem Lab Med 2001; 39:666-674.
35. Yudkin JS, Stehouwer CD, Emeis JJ, Coppack SW:C-reactive protein in healthy subjects:associations with obesity, insulin resistance, and endothelial dysfunction:a potencial role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 1999; 19:972-978.
36. Chodorowska G, Wojnowska D, Juszkiewicz-Borowiec M. C-reactive protein and alpha2-macroglobulin plasma activity in medium severe and severe psoriasis. J Eur Acad Dermatol Venereol 2004; 18:180-183.