Diagnosis of extrapulmonary tuberculosis using the Xpert® MTB/RIF assay

Expert Review of Anti-Infective Therapy

Volumn 10, Issue 6, 2012, Pages 631-635

  Lawn, Stephen D ^a,b   Zumla, Alimuddin I ^c,d  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

diagnosis; extrapulmonary; nucleic acid amplification test; tuberculosis; Xpert

Indexed keywords

ASPIRATION BIOPSY; BACTERIUM IDENTIFICATION; BIOASSAY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; EXTRAPULMONARY TUBERCULOSIS; FALSE POSITIVE RESULT; FLUORESCENCE MICROSCOPY; GOLD STANDARD; HISTOPATHOLOGY; HUMAN; INTERMETHOD COMPARISON; MOLECULAR DIAGNOSIS; MYCOBACTERIUM TUBERCULOSIS; OUTCOME ASSESSMENT; REVIEW; SENSITIVITY AND SPECIFICITY; SPUTUM ANALYSIS;

EID: 84863184490     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/eri.12.43     Document Type: Review

References (15)

1. Lawn SD, Zumla AI. Tuberculosis. Lancet 378, 57-72 (2011).
2. Centers for Disease Control and Prevention. Updated guidelines for the use of nucleic acid amplification tests in the diagnosis of tuberculosis. MMWR Morb. Mortal. Wkly Rep. 58, 7-10 (2009).
3. Lawn SD, Nicol MP. Xpert(R) MTB/RIF assay: development, evaluation and implementation of a new rapid molecular diagnostic for tuberculosis and rifampicin resistance. Future Microbiol. 6, 1067-1082 (2011).
4. Boehme CC, Nabeta P, Hillemann D et al. Rapid molecular detection of tuberculosis and rifampin resistance. N. Engl. J. Med. 363, 1005-1015 (2010).
5. Tortoli E, Russo C, Piersimoni C et al. Clinical validation of Xpert MTB/RIF for the diagnosis of extrapulmonary tuberculosis. Eur. Respir. J. doi:10.1183/09031936.00176311 (2012) (Epub ahead of print).
6. Armand S, Vanhuls P, Delcroix G, Courcol R, Lemaitre N. Comparison of the Xpert MTB/RIF test with an IS6110-TaqMan real-time PCR assay for direct detection of Mycobacterium tuberculosis in respiratory and nonrespiratory specimens. J. Clin. Microbiol. 49, 1772-1776 (2011).
7. Causse M, Ruiz P, Juan Bautista GA, Casal M. Comparison of two molecular methods for the rapid diagnosis of extrapulmonary tuberculosis. J. Clin. Microbiol. 49, 3065-3067 (2011).
8. Friedrich SO, von Groote-Bidlingmaier F, Diacon AH. Xpert MTB/RIF assay for diagnosis of pleural tuberculosis. J. Clin. Microbiol. 49, 4341-4342 (2011).
9. Hillemann D, Rusch-Gerdes S, Boehme C, Richter E. Rapid molecular detection of extrapulmonary tuberculosis by the automated GeneXpert MTB/RIF System. J. Clin. Microbiol. 49, 1202-1205 (2011).
10. Ligthelm LJ, Nicol MP, Hoek KG et al. Xpert MTB/RIF for rapid diagnosis of tuberculous lymphadenitis from fine-needle-aspiration biopsy specimens. J. Clin. Microbiol. 49, 3967-3970 (2011).
11. Moure R, Munoz L, Torres M, Santin M, Martin R, Alcaide F. Rapid detection of Mycobacterium tuberculosis complex and rifampin resistance in smear-negative clinical samples by use of an integrated real-time PCR method. J. Clin. Microbiol. 49, 1137-1139 (2011).
12. Vadwai V, Boehme C, Nabeta P, Shetty A, Alland D, Rodrigues C. Xpert MTB/RIF, a new pillar in the diagnosis of extrapulmonary tuberculosis? J. Clin. Microbiol. 49, 2540-2545 (2011).
13. Nicol MP, Workman L, Isaacs W et al. Accuracy of the Xpert MTB/RIF test for the diagnosis of pulmonary tuberculosis in children admitted to hospital in Cape Town, South Africa: a descriptive study. Lancet Infect. Dis. 11, 819-824 (2011).
14. Lawn SD, Brooks SV, Kranzer K et al. Screening for HIV-associated tuberculosis and rifampicin resistance before antiretroviral therapy using the Xpert MTB/RIF assay: a prospective study. PLoS Med. 8, E1001067 (2011).
15. Lawn SD, Wood R. Tuberculosis in antiretroviral treatment services in resource-limited settings: addressing the challenges of screening and diagnosis. J. Infect. Dis. 204(Suppl. 4), S1159-S1167 (2011). WHO. Tuberculosis diagnostics automated DNA test. www.who.int/tb/features-archive/xpert-factsheet. pdf