Dihydroartemisinin induces endoplasmic reticulum stress-mediated apoptosis in HepG2 human hepatoma cells

Tumori

Volumn 97, Issue 6, 2011, Pages 771-780

  Gao, Xiaoling ^a   Luo, Ziguo ^a   Xiang, Tingxiu ^a   Wang, Kejian ^a   Li, Jian ^a   Wang, Pilong ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Bax; Bcl 2; Calcium; Dihydroartemisinin; Endoplasmic reticulum stress; GADD153; Reactive oxygen species

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACETYLCYSTEINE; CALCIUM ION; DIHYDROARTEMISININ; FLUORESCEIN ISOTHIOCYANATE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL ASSAY; CELL PROLIFERATION; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; HEPATOMA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PROTEIN EXPRESSION; SPECTROFLUOROMETRY; STAINING; WESTERN BLOTTING;

ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARTEMISININS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPECTROMETRY, FLUORESCENCE; TRANSCRIPTION FACTOR CHOP;

EID: 84863167424     PISSN: 03008916     EISSN: 20382529     Source Type: Journal    
DOI: 10.1700/1018.11095     Document Type: Article

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