Role of inflammation in the pathogenesis of arterial stiffness

Yonsei Medical Journal

Volumn 53, Issue 2, 2012, Pages 258-261

  Park, Sungha ^a   Lakatta, Edward G ^b  

^a Yonsei University College of Medicine   (South Korea)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Angiotensin II; Arterial stiffness; Inflammation

Indexed keywords

ANGIOTENSIN II; C REACTIVE PROTEIN; CILNIDIPINE; INTERLEUKIN 1; INTERLEUKIN 17; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; NIFEDIPINE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TEMOCAPRIL; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VALSARTAN;

ARTERIAL STIFFNESS; ARTICLE; CARDIOVASCULAR RISK; DISEASE ASSOCIATION; FIBROMUSCULAR DYSPLASIA; HUMAN; HYPERTENSION; INFLAMMATION; PATHOGENESIS; PULSE WAVE; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION;

ANGIOTENSIN II; HUMANS; INFLAMMATION; MATRIX METALLOPROTEINASES; VASCULAR STIFFNESS;

EID: 84863148944     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2012.53.2.258     Document Type: Article

References (42)

1. Franklin SS, Gustin W 4th, Wong ND, Larson MG, Weber MA, Kannel WB, et al. Hemodynamic patterns of age-related changes in blood pressure. The Framingham Heart Study. Circulation 1997;96:308-15.
2. Laurent S, Katsahian S, Fassot C, Tropeano AI, Gautier I, Laloux B, et al. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension. Stroke 2003;34:1203-6.
3. Domanski MJ, Mitchell GF, Norman JE, Exner D V, Pitt B, Pfeffer MA. Independent prognostic information provided by sphygmo-manometrically determined pulse pressure and mean arterial pressure in patients with left ventricular dysfunction. J Am Coll Cardi-ol 1999;33:951-8.
4. Abramson JL, Weintraub WS, Vaccarino V. Association between pulse pressure and C-reactive protein among apparently healthy US adults. Hypertension 2002;39:197-202.
5. Boutouyrie P, Tropeano AI, Asmar R, Gautier I, Benetos A, Lacol-ley P, et al. Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study. Hypertension 2002;39:10-5.
6. Sutton-Tyrrell K, Najjar SS, Boudreau RM, Venkitachalam L, Ku-pelian V, Simonsick EM, et al. Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation 2005;111:3384-90.
7. Zieman SJ, Melenovsky V, Kass DA. Mechanisms, pathophysiol-ogy, and therapy of arterial stiffness. Arterioscler Thromb Vasc Biol 2005;25:932-43.
8. Scuteri A, Najjar SS, Muller DC, Andres R, Hougaku H, Metter EJ, et al. Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness. J Am Coll Cardiol 2004;43:1388-95. 9.
9. Dart AM, Kingwell BA. Pulse pressure--a review of mechanisms and clinical relevance. J Am Coll Cardiol 2001;37:975-84.
10. Xu C, Zarins CK, Pannaraj PS, Bassiouny HS, Glagov S. Hyper-cholesterolemia superimposed by experimental hypertension induces differential distribution of collagen and elastin. Arterioscler Thromb Vasc Biol 2000;20:2566-72.
11. Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation 2003;107:139-46.
12. Lakatta EG. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging. Circulation 2003;107:490-7.
13. Virmani R, Avolio AP, Mergner WJ, Robinowitz M, Herderick EE, Cornhill JF, et al. Effect of aging on aortic morphology in populations with high and low prevalence of hypertension and atherosclerosis. Comparison between occidental and Chinese communities. Am J Pathol 1991;139:1119-29.
14. Jacob MP. Extracellular matrix remodeling and matrix metallo-proteinases in the vascular wall during aging and in pathological conditions. Biomed Pharmacother 2003;57:195-202.
15. Li Z, Froehlich J, Galis ZS, Lakatta EG. Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats. Hypertension 1999;33:116-23.
16. Wang M, Lakatta EG. Altered regulation of matrix metalloprotein-ase-2 in aortic remodeling during aging. Hypertension 2002;39: 865-73.
17. Pauly RR, Passaniti A, Bilato C, Monticone R, Cheng L, Papado-poulos N, et al. Migration of cultured vascular smooth muscle cells through a basement membrane barrier requires type IV collagenase activity and is inhibited by cellular differentiation. Circ Res 1994;75:41-54.
18. Wendt T, Bucciarelli L, Qu W, Lu Y, Yan SF, Stern DM, et al. Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: insights into the pathogenesis of macrovascular complications in diabetes. Curr Atheroscler Rep 2002;4:228-37.
19. Galis ZS, Khatri JJ. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ Res 2002;90:251-62.
20. Wang M, Zhang J, Jiang LQ, Spinetti G, Pintus G, Monticone R, et al. Proinfammatory profle within the grossly normal aged human aortic wall. Hypertension 2007;50:219-27.
21. van der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, et al. Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med 2000;192:1731-44.
22. Csiszar A, Ungvari Z, Edwards JG, Kaminski P, Wolin MS, Koller A, et al. Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res 2002;90:1159-66.
23. Spinetti G, Wang M, Monticone R, Zhang J, Zhao D, Lakatta EG. Rat aortic MCP-1 and its receptor CCR2 increase with age and alter vascular smooth muscle cell function. Arterioscler Thromb Vasc Biol 2004;24:1397-402.
24. Csiszar A, Ungvari Z, Koller A, Edwards JG, Kaley G. Aging-induced proinfammatory shift in cytokine expression profle in coronary arteries. FASEB J 2003;17:1183-5.
25. Gerli R, Monti D, Bistoni O, Mazzone AM, Peri G, Cossarizza A, et al. Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians. Mech Ageing Dev 2000;121:37-46.
26. Belmin J, Bernard C, Corman B, Merval R, Esposito B, Tedgui A. Increased production of tumor necrosis factor and interleukin-6 by arterial wall of aged rats. Am J Physiol 1995;268:H2288-93.
27. Ishibashi M, Hiasa K, Zhao Q, Inoue S, Ohtani K, Kitamoto S, et al. Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular infamma-tion and remodeling. Circ Res 2004;94:1203-10.
28. Jiang Y, Beller DI, Frendl G, Graves DT. Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. J Immunol 1992;148:2423-8.
29. Viedt C, Vogel J, Athanasiou T, Shen W, Orth SR, Kübler W, et al. Monocyte chemoattractant protein-1 induces proliferation and in-terleukin-6 production in human smooth muscle cells by differential activation of nuclear factor-kappaB and activator protein-1. Arterioscler Thromb Vasc Biol 2002;22:914-20.
30. Venugopal SK, Devaraj S, Yuhanna I, Shaul P, Jialal I. Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells. Circulation 2002;106:1439-41.
31. Torzewski M, Rist C, Mortensen RF, Zwaka TP, Bienek M, Waltenberger J, et al. C-reactive protein in the arterial intima: role of C-reactive protein receptor-dependent monocyte recruitment in atherogenesis. Arterioscler Thromb Vasc Biol 2000;20:2094-9.
32. Pasceri V, Willerson JT, Yeh ET. Direct proinfammatory effect of C-reactive protein on human endothelial cells. Circulation 2000; 102:2165-8.
33. Mahmud A, Feely J. Arterial stiffness is related to systemic infam-mation in essential hypertension. Hypertension 2005;46:1118-22.
34. Nagano M, Nakamura M, Sato K, Tanaka F, Segawa T, Hiramori K. Association between serum Creactive protein levels and pulse wave velocity: a population-based cross-sectional study in a general population. Atherosclerosis 2005;180:189-95.
35. Mattace-Raso FU, van der Cammen TJ, van der Meer IM, Schalekamp MA, Asmar R, Hofman A, et al. C-reactive protein and arterial stiffness in older adults: the Rotterdam Study. Atherosclerosis 2004;176:111-6.
36. Pasceri V, Cheng JS, Willerson JT, Yeh ET. Modulation of C-reactive protein-mediated monocyte chemoattractant protein-1 induction in human endothelial cells by anti-atherosclerosis drugs. Circulation 2001;103:2531-4.
37. Boos CJ, Lip G Y. Elevated high-sensitive C-reactive protein, large arterial stiffness and atherosclerosis: a relationship between inflammation and hypertension? J Hum Hypertens 2005;19:511-3.
38. Patel RS, Al Mheid I, Morris AA, Ahmed Y, Kavtaradze N, Ali S, et al. Oxidative stress is associated with impaired arterial elasticity. Atherosclerosis 2011;218:90-5.
39. McEniery CM, Spratt M, Munnery M, Yarnell J, Lowe GD, Rum-ley A, et al. An analysis of prospective risk factors for aortic stiffness in men: 20-year follow-up from the Caerphilly prospective study. Hypertension 2010;56:36-43.
40. Mäki-Petäjä KM, Hall FC, Booth AD, Wallace SM, Yasmin, Bearcroft PW, et al. Rheumatoid arthritis is associated with increased aortic pulse-wave velocity, which is reduced by anti-tumor necrosis factor-alpha therapy. Circulation 2006;114:1185-92.
41. Takami T, Shigemasa M. Efficacy of various antihypertensive agents as evaluated by indices of vascular stiffness in elderly hypertensive patients. Hypertens Res 2003;26:609-14.
42. Munakata M, Nagasaki A, Nunokawa T, Sakuma T, Kato H, Yo-shinaga K, et al. Effects of valsartan and nifedipine coat-core on systemic arterial stiffness in hypertensive patients. Am J Hyper-tens 2004;17(11 Pt 1):1050-5.