메뉴 건너뛰기




Volumn 81, Issue 3, 2012, Pages 348-355

Desensitization and trafficking of μ-opioid receptors in locus ceruleus neurons: Modulation by kinases

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; HEPARIN; MU OPIATE RECEPTOR; PROTEIN KINASE; STAUROSPORINE;

EID: 84863134139     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.076208     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 33749059766 scopus 로고    scopus 로고
    • Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor
    • DOI 10.1016/j.cell.2006.08.037, PII S0092867406011597
    • Armstrong N, Jasti J, Beich-Frandsen M, and Gouaux E (2006) Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor. Cell 127:85-97. (Pubitemid 44466635)
    • (2006) Cell , vol.127 , Issue.1 , pp. 85-97
    • Armstrong, N.1    Jasti, J.2    Beich-Frandsen, M.3    Gouaux, E.4
  • 3
    • 33646084606 scopus 로고    scopus 로고
    • Separation of μ-opioid receptor desensitization and internalization: Endogenous receptors in primary neuronal cultures
    • DOI 10.1523/JNEUROSCI.0303-06.2006
    • Arttamangkul S, Torrecilla M, Kobayashi K, Okano H, and Williams JT (2006) Separation of μ-opioid receptor desensitization and internalization: endogenous receptors in primary neuronal cultures. J Neurosci 26:4118-4125. (Pubitemid 44315433)
    • (2006) Journal of Neuroscience , vol.26 , Issue.15 , pp. 4118-4125
    • Arttamangkul, S.1    Torrecilla, M.2    Kobayashi, K.3    Okano, H.4    Williams, J.T.5
  • 4
    • 9444274109 scopus 로고    scopus 로고
    • Protein kinase C activation enhances morphine-induced rapid desensitization of μ-opioid receptors in mature rat locus ceruleus neurons
    • DOI 10.1124/mol.104.004747
    • Bailey CP, Kelly E, and Henderson G (2004) Protein kinase C activation enhances morphine-induced rapid desensitization of μ-opioid receptors in mature rat locus ceruleus neurons. Mol Pharmacol 66:1592-1598. (Pubitemid 39564786)
    • (2004) Molecular Pharmacology , vol.66 , Issue.6 , pp. 1592-1598
    • Bailey, C.P.1    Kelly, E.2    Henderson, G.3
  • 7
    • 79956302829 scopus 로고    scopus 로고
    • Cellular morphine tolerance produced by β-arrestin-1-dependent impairment of μ-opioid receptor resensitization
    • Dang VC, Chieng B, Azriel Y, and Christie MJ (2011) Cellular morphine tolerance produced by β-arrestin-1-dependent impairment of μ-opioid receptor resensitization. J Neurosci 31:7122-7130.
    • (2011) J Neurosci , vol.31 , pp. 7122-7130
    • Dang, V.C.1    Chieng, B.2    Azriel, Y.3    Christie, M.J.4
  • 8
    • 84857476249 scopus 로고    scopus 로고
    • Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons
    • Dang VC and Christie MJ (2011) Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons. Br J Pharmacol http://dx.doi.org/10.1111/j.1476-5381.2011.01482.x.
    • (2011) Br J Pharmacol
    • Dang, V.C.1    Christie, M.J.2
  • 9
    • 63849297063 scopus 로고    scopus 로고
    • Two distinct mechanisms mediate acute μ-opioid receptor desensitization in native neurons
    • Dang VC, Napier IA, and Christie MJ (2009) Two distinct mechanisms mediate acute μ-opioid receptor desensitization in native neurons. J Neurosci 29:3322-3327.
    • (2009) J Neurosci , vol.29 , pp. 3322-3327
    • Dang, V.C.1    Napier, I.A.2    Christie, M.J.3
  • 10
    • 25144435574 scopus 로고    scopus 로고
    • Morphine-induced μ-opioid receptor desensitization
    • Dang VC and Williams JT (2005) Morphine-induced μ-opioid receptor desensitization. Mol Pharmacol 68:1127-1132.
    • (2005) Mol Pharmacol , vol.68 , pp. 1127-1132
    • Dang, V.C.1    Williams, J.T.2
  • 11
    • 78650854802 scopus 로고    scopus 로고
    • β-Arrestins as regulators of signal termination and transduction: How do they determine what to scaffold?
    • DeFea KA (2011) β-Arrestins as regulators of signal termination and transduction: how do they determine what to scaffold? Cell Signal 23:621-629.
    • (2011) Cell Signal , vol.23 , pp. 621-629
    • DeFea, K.A.1
  • 12
    • 80051615294 scopus 로고    scopus 로고
    • Agonist-selective patterns of μ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies
    • Doll C, Konietzko J, Pöll F, Koch T, Höllt V, and Schulz S (2011) Agonist-selective patterns of μ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies. Br J Pharmacol 164:298-307.
    • (2011) Br J Pharmacol , vol.164 , pp. 298-307
    • Doll, C.1    Konietzko, J.2    Pöll, F.3    Koch, T.4    Höllt, V.5    Schulz, S.6
  • 14
    • 33646414189 scopus 로고    scopus 로고
    • The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
    • Gurevich VV and Gurevich EV (2006) The structural basis of arrestin-mediated regulation of G-protein-coupled receptors. Pharmacol Ther 110:465-502.
    • (2006) Pharmacol Ther , vol.110 , pp. 465-502
    • Gurevich, V.V.1    Gurevich, E.V.2
  • 15
    • 0025938571 scopus 로고
    • Transient homologous μ-opioid receptor desensitization in rat locus coeruleus neurons
    • Harris GC and Williams JT (1991) Transient homologous μ-opioid receptor desensitization in rat locus coeruleus neurons. J Neurosci 11:2574-2581.
    • (1991) J Neurosci , vol.11 , pp. 2574-2581
    • Harris, G.C.1    Williams, J.T.2
  • 16
    • 33745018099 scopus 로고    scopus 로고
    • The role of opioid receptor phosphorylation and trafficking in adaptations to persistent opioid treatment
    • DOI 10.1159/000093044
    • Johnson EE, Christie MJ, and Connor M (2005) The role of opioid receptor phosphorylation and trafficking in adaptations to persistent opioid treatment. Neurosignals 14:290-302. (Pubitemid 43877701)
    • (2006) NeuroSignals , vol.14 , Issue.6 , pp. 290-302
    • Johnson, E.E.1    Christie, M.J.2    Connor, M.3
  • 18
    • 40349114499 scopus 로고    scopus 로고
    • Agonist-selective mechanisms of GPCR desensitization
    • DOI 10.1038/sj.bjp.0707604, PII 0707604
    • Kelly E, Bailey CP, and Henderson G (2008) Agonist-selective mechanisms of GPCR desensitization. Br J Pharmacol 153 (Suppl 1):S379-S388. (Pubitemid 351340999)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.SUPPL. 1
    • Kelly, E.1    Bailey, C.P.2    Henderson, G.3
  • 19
    • 27144541891 scopus 로고    scopus 로고
    • Chemical genetic engineering of G protein-coupled receptor kinase 2
    • DOI 10.1074/jbc.M507594200
    • Kenski DM, Zhang C, von Zastrow M, and Shokat KM (2005) Chemical genetic engineering of G protein-coupled receptor kinase 2. J Biol Chem 280:35051-35061. (Pubitemid 41504640)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.41 , pp. 35051-35061
    • Kenski, D.M.1    Zhang, C.2    Von Zastrow, M.3    Shokat, K.M.4
  • 20
    • 0942287665 scopus 로고    scopus 로고
    • Phospholipase D2 modulates agonist-induced μ-opioid receptor desensitization and resensitization
    • DOI 10.1046/j.1471-4159.2003.02189.x
    • Koch T, Brandenburg LO, Liang Y, Schulz S, Beyer A, Schröder H, and Höllt V (2004) Phospholipase D2 modulates agonist-induced μ-opioid receptor desensitization and resensitization. J Neurochem 88:680-688. (Pubitemid 38140212)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.3 , pp. 680-688
    • Koch, T.1    Brandenburg, L.-O.2    Liang, Y.3    Schulz, S.4    Beyer, A.5    Schroder, H.6    Hollt, V.7
  • 21
    • 0031726194 scopus 로고    scopus 로고
    • Agonist induced homologous desensitization of μ-opioid receptors mediated by G protein-coupled receptor kinases is dependent on agonist efficacy
    • Kovoor A, Celver JP, Wu A, and Chavkin C (1998) Agonist induced homologous desensitization of μ-opioid receptors mediated by G protein-coupled receptor kinases is dependent on agonist efficacy. Mol Pharmacol 54:704-711. (Pubitemid 28480974)
    • (1998) Molecular Pharmacology , vol.54 , Issue.4 , pp. 704-711
    • Kovoor, A.1    Celver, J.P.2    Wu, A.3    Chavkin, C.4
  • 23
    • 69249115724 scopus 로고    scopus 로고
    • Differential effect of membrane cholesterol removal on μ- and μ-opioid receptors: A parallel comparison of acute and chronic signaling to adenylyl cyclase
    • Levitt ES, Clark MJ, Jenkins PM, Martens JR, and Traynor JR (2009) Differential effect of membrane cholesterol removal on μ- and μ-opioid receptors: a parallel comparison of acute and chronic signaling to adenylyl cyclase. J Biol Chem 284: 22108-22122.
    • (2009) J Biol Chem , vol.284 , pp. 22108-22122
    • Levitt, E.S.1    Clark, M.J.2    Jenkins, P.M.3    Martens, J.R.4    Traynor, J.R.5
  • 24
    • 0027992129 scopus 로고
    • Expression, purification, and characterization of the G protein-coupled receptor kinase GRK6
    • Loudon RP and Benovic JL (1994) Expression, purification, and characterization of the G protein-coupled receptor kinase GRK6. J Biol Chem 269:22691-22697. (Pubitemid 24273379)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.36 , pp. 22691-22697
    • Loudon, R.P.1    Benovic, J.L.2
  • 25
    • 25144481466 scopus 로고    scopus 로고
    • Phosphorylation of EEA1 by p38 MAP kinase regulates μ opioid receptor endocytosis
    • DOI 10.1038/sj.emboj.7600799, PII 7600799
    • Macé G, Miaczynska M, Zerial M, and Nebreda AR (2005) Phosphorylation of EEA1 by p38 MAP kinase regulates μ opioid receptor endocytosis. EMBO J 24:3235-3246. (Pubitemid 41348698)
    • (2005) EMBO Journal , vol.24 , Issue.18 , pp. 3235-3246
    • Mace, G.1    Miaczynska, M.2    Zerial, M.3    Nebreda, A.R.4
  • 27
    • 0041458603 scopus 로고    scopus 로고
    • ScanImage: Flexible software for operating laser scanning microscopes
    • Pologruto TA, Sabatini BL, and Svoboda K (2003) ScanImage: flexible software for operating laser scanning microscopes. Biomed Eng Online 2:13.
    • (2003) Biomed Eng Online , vol.2 , pp. 13
    • Pologruto, T.A.1    Sabatini, B.L.2    Svoboda, K.3
  • 28
    • 33749079184 scopus 로고    scopus 로고
    • Cargo Regulates Clathrin-Coated Pit Dynamics
    • DOI 10.1016/j.cell.2006.08.035, PII S0092867406011573
    • Puthenveedu MA and von Zastrow M (2006) Cargo regulates clathrin-coated pit dynamics. Cell 127:113-124. (Pubitemid 44466633)
    • (2006) Cell , vol.127 , Issue.1 , pp. 113-124
    • Puthenveedu, M.A.1    Von, Z.M.2
  • 29
    • 79953003987 scopus 로고    scopus 로고
    • Recovery from μ-opioid receptor desensitization after chronic treatment with morphine and methadone
    • Quillinan N, Lau EK, Virk M, von Zastrow M, and Williams JT (2011) Recovery from μ-opioid receptor desensitization after chronic treatment with morphine and methadone. J Neurosci 31:4434-4443.
    • (2011) J Neurosci , vol.31 , pp. 4434-4443
    • Quillinan, N.1    Lau, E.K.2    Virk, M.3    Von Zastrow, M.4    Williams, J.T.5
  • 30
    • 66249144426 scopus 로고    scopus 로고
    • The structure and function of G-protein-coupled receptors
    • Rosenbaum DM, Rasmussen SG, and Kobilka BK (2009) The structure and function of G-protein-coupled receptors. Nature 459:356-363.
    • (2009) Nature , vol.459 , pp. 356-363
    • Rosenbaum, D.M.1    Rasmussen, S.G.2    Kobilka, B.K.3
  • 31
    • 4444311166 scopus 로고    scopus 로고
    • Morphine induces terminal μ-opioid receptor desensitization by sustained phosphorylation of serine-375
    • DOI 10.1038/sj.emboj.7600334
    • Schulz S, Mayer D, Pfeiffer M, Stumm R, Koch T, and Höllt V (2004) Morphine induces terminal μ-opioid receptor desensitization by sustained phosphorylation of serine-375. EMBO J 23:3282-3289. (Pubitemid 39209152)
    • (2004) EMBO Journal , vol.23 , Issue.16 , pp. 3282-3289
    • Schulz, S.1    Mayer, D.2    Pfeiffer, M.3    Stumm, R.4    Koch, T.5    Hollt, V.6
  • 32
    • 72049124287 scopus 로고    scopus 로고
    • X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
    • Sobolevsky AI, Rosconi MP, and Gouaux E (2009) X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature 462:745-756.
    • (2009) Nature , vol.462 , pp. 745-756
    • Sobolevsky, A.I.1    Rosconi, M.P.2    Gouaux, E.3
  • 33
    • 41149178141 scopus 로고    scopus 로고
    • Agonist-specific regulation of μ-opioid receptor desensitization and recovery from desensitization
    • DOI 10.1124/mol.107.042952
    • Virk MS and Williams JT (2008) Agonist-specific regulation of μ-opioid receptor desensitization and recovery from desensitization. Mol Pharmacol 73:1301-1308. (Pubitemid 351439212)
    • (2008) Molecular Pharmacology , vol.73 , Issue.4 , pp. 1301-1308
    • Virk, M.S.1    Williams, J.T.2
  • 34
    • 0021178713 scopus 로고
    • Membrane properties of rat locus coeruleus neurones
    • DOI 10.1016/0306-4522(84)90265-3
    • Williams JT, North RA, Shefner SA, Nishi S, and Egan TM (1984) Membrane properties of rat locus coeruleus neurones. Neuroscience 13:137-156. (Pubitemid 14033088)
    • (1984) Neuroscience , vol.13 , Issue.1 , pp. 137-156
    • Williams, J.T.1    North, R.A.2    Shefner, S.A.3
  • 36
    • 48249144810 scopus 로고    scopus 로고
    • Agonist-selective signaling is determined by the receptor location within the membrane domains
    • Zheng H, Chu J, Qiu Y, Loh HH, and Law PY (2008) Agonist-selective signaling is determined by the receptor location within the membrane domains. Proc Natl Acad Sci USA 105:9421-9426.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9421-9426
    • Zheng, H.1    Chu, J.2    Qiu, Y.3    Loh, H.H.4    Law, P.Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.