Angiotensin-converting enzyme-2 overexpression improves left ventricular remodeling and function in a rat model of diabetic cardiomyopathy

Journal of the American College of Cardiology

Volumn 59, Issue 8, 2012, Pages 739-747

  Dong, Bo ^a,b   Yu, Qing Tao ^a,c   Dai, Hong Yan ^a   Gao, Yan Yan ^a   Zhou, Zhao Li ^a   Zhang, Lei ^a   Jiang, Hong ^a   Gao, Fei ^a   Li, Shu Ying ^a   Zhang, Yue Hui ^a   Bian, Hong Jun ^a   Liu, Chun Xi ^a   Wang, Nan ^a   Xu, Hui ^a   Pan, Chun Ming ^d   Song, Huai Dong ^d   Zhang, Cheng ^a   Zhang, Yun ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c People's Hospital of Huai Yin District   (China)

^d SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

angiotensin II; angiotensin converting enzyme 2; diabetic cardiomyopathy; gene therapy; heart failure

Indexed keywords

ADENOVIRUS VECTOR; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; ANGIOTENSIN[1-7]; COLLAGEN; COLLAGEN TYPE 1; DIPEPTIDYL CARBOXYPEPTIDASE; ENHANCED GREEN FLUORESCENT PROTEIN; GELATINASE A; GELATINASE B; LOSARTAN; STREPTOZOCIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN DEGRADATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DIASTOLE; DOWN REGULATION; ENZYME ACTIVITY; FIBROBLAST; GENE TRANSFER; GENETIC TRANSFECTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE SIZE; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; STREPTOZOCIN DIABETES; SYSTOLE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; BLOTTING, WESTERN; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; ECHOCARDIOGRAPHY; GENE EXPRESSION REGULATION; HEART VENTRICLES; IMMUNOHISTOCHEMISTRY; MALE; MYOCARDIUM; PEPTIDYL-DIPEPTIDASE A; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84863116259     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2011.09.071     Document Type: Article

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