Pulsed Ultrasound and Dimethylsulfoxide Gel Treatment Reduces the Expression of Pro-Inflammatory Molecules in an Animal Model of Muscle Injury

Ultrasound in Medicine and Biology

Volumn 38, Issue 8, 2012, Pages 1470-1475

  Engelmann, Julia ^a   Vitto, Marcelo F ^a   Cesconetto, Patricia A ^a   Silveira, Paulo C ^a   Possato, Jonathann C ^a   Pinho, Ricardo A ^a   Paula, Marcos Marques S ^a   Victor, Eduardo G ^a   De Souza, Claudio T ^a  

^a UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

Author keywords

Cytokines; Inflammatory response; Muscle healing; Physiotherapy

Indexed keywords

ANIMAL MODEL; CYTOKINES; FOUR-GROUP; GEL TREATMENT; INFLAMMATORY RESPONSE; LOW-INTENSITY PULSED ULTRASOUND; MUSCLE INJURIES; PROINFLAMMATORY; PROINFLAMMATORY MOLECULES; PROTEIN LEVEL; PULSED ULTRASOUNDS; WESTERN BLOTS; WISTAR RAT;

PHOSPHORYLATION; PHYSICAL THERAPY; PROTEINS;

MOLECULES;

DIMETHYL SULFOXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DENSITOMETRY; IMMUNOBLOTTING; LOW ENERGY RADIATION; MALE; MUSCLE INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; PULSED ULTRASOUND; RAT; ULTRASOUND;

ANIMALS; CYTOKINES; FREE RADICAL SCAVENGERS; GELS; MALE; MUSCLE, SKELETAL; RATS; RATS, WISTAR; ULTRASONIC THERAPY; ULTRASONOGRAPHY, DOPPLER, PULSED;

EID: 84863108622     PISSN: 03015629     EISSN: 1879291X     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2012.03.020     Document Type: Article

References (32)

1. Bakkar N., Guttridge D.C. NF-κB signaling: A tale of two pathways in skeletal myogenesis. Physiol Rev 2010, 90:495-511.
2. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
3. Byl N.N. The use of ultrasound as an enhancer for transcutaneous drug delivery: Phonophoresis. Phys Ther 1995, 75:539-553.
4. Chan Y.S., Hsu K.Y., Kuo C.H., Lee S.D., Chen S.C., Chen W.J., Ueng S.W. Using low-intensity pulsed ultrasound to improve muscle healing after laceration injury: An in vitro and in vivo study. Ultrasound Med Biol 2010, 36:743-751.
5. Farnebo S., Lars-Erik K., Ingrid S., Sjögren F., Folke S. Continuous assessment of concentrations of cytokines in experimental injuries of the extremity. Int J Clin Exp Med 2009, 2:354-362.
6. Francis M.D., Horn P.A., McCreary L.D. Penetration and effect of topically applied dimethylsulfoxide or indomethacin on adjuvant arthritis in the rat. Arthritis Rheum 1983, 26:861-865.
7. Gleizal A., Li S., Pialat J.B., Beziat J.L. Transcriptional expression of calvarial bone after treatment with low-intensity ultrasound: An in vitro study. Ultrasound Med Biol 2006, 32:1569-1574.
8. Görög P., Kovács I.B. Effect of dimethylsulfoxide (DMSO) on various experimental inflammations. Curr Ther Res Clin Exp 1968, 10:486-492.
9. Gupta S. A decision between life and death during TNF-α-induced signaling. J Clin Immunol 2002, 22:185-194.
10. Järvinen T.A., Järvinen T.L., Kääriäinen M., Aärimaa V., Vaittinen S., Kalimo H., Järvinen M. Muscle injuries: Optimizing recovery. Best Pract Res Clin Rheumatol 2007, 21:317-331.
11. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
12. Langen R.C., Schols A.M., Kelders M.C., Van Der Velden J.L., Wouters E.F., Janssen-Heininger Y.M. Tumor necrosis factor α inhibits myogenesis through redox-dependent and -independent pathways. Am J Physiol Cell Physiol 2002, 283:C714-C721.
13. Langen R.C., Schols A.M., Kelders M.C., Wouters E.F., Janssen-Heininger Y.M. Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-κB. FASEB J 2001, 15:1169-1180.
14. Li Y.P., Schwartz R.J., Waddell I.D., Holloway B.R., Reid M.B. Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-κB activation in response to tumor necrosis factor alpha. FASEB J 1998, 12:871-880.
15. McLoughlin T.J., Tsivitse S.K., Edwards J.A., Aiken B.A., Pizza F.X. Deferoxamine reduces and nitric oxide synthase inhibition increases neutrophil-mediated myotube injury. Cell Tissue Res 2003, 313:313-319.
16. Mourkioti F., Kratsios P., Luedde T., Song Y.H., Delafontaine P., Adami R., Parente V., Bottinelli R., Pasparakis M., Rosenthal N. Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. J Clin Invest 2006, 116:2945-2954.
17. Piedade M.C., Galhardo M.S., Battlehner C.N., Ferreira M.A., Caldini E.G., de Toledo O.M. Effect of ultrasound therapy on the repair of gastrocnemius muscle injury in rats. Ultrasonics 2008, 48:403-411.
18. Polat B.E., Blankschtein D., Langer R. Low-frequency sonophoresis: Application to the transdermal delivery of macromolecules and hydrophilic drugs. Expert Opin Drug Deliv 2010, 7:1415-1432.
19. Reher P., Doan N., Bradnock B., Meghji S., Harris M. Effect of ultrasound on the production of IL-8, basic FGF and VEGF. Cytokine 1999, 11:416-423.
20. Rizzi C.F., Mauriz J.L., Corrêa D.S.F. Effects of low-level LaserTherapy (LLLT) on the nuclear factor (NF)- κB signaling pathway in traumatized muscle. Lasers Surg Med 2006, 38:704-713.
21. Saliba S., Mistry D.J., Perrin D.H., Gieck J., Weltman A. Phonophoresis and the absorption of dexamethasone in the presence of an occlusive dressing. J Athl Train 2007, 42:349-354.
22. Signori L.U., Costa S.T., Neto A.F., Pizzolotto R.M., Beck C., Sbruzzi G., Silva A.M., Plentz R.D. Haematological effect of pulsed ultrasound in acute muscular inflammation in rats. Physiotherapy 2011, 97:163-169.
23. Silveira P.C., Victor E.G., Schefer D., Silva L.A., Streck E.L., Paula M.M., Pinho R.A. Effects of therapeutic pulsed ultrasound and dimethylsulfoxide (DMSO) phonophoresis on parameters of oxidative stress in traumatized muscle. Ultrasound Med Biol 2010, 36:44-50.
24. Smith C., Kruger M.J., Smith R.M., Myburgh K.H. The inflammatory response to skeletal muscle injury: Illuminating complexities. Sports Med 2008, 38:947-969.
25. Summan M., McKinstry M., Warren G.L., Hulderman T., Mishra D., Brumbaugh K., Luster M.I., Simeonova P.P. Inflammatory mediators and skeletal muscle injury: A DNA microarray analysis. J Interferon Cytokine Res 2003, 23:237-245.
26. Takikawa S., Matsui N., Kokubu T., Tsunoda M., Fujioka H., Mizuno K., Azuma Y. Low-intensity pulsed ultrasound initiates bone healing in rat nonunion fracture model. J Ultrasound Med 2001, 20:197-205.
27. Thaloor D., Miller K.J., Gephart J., Mitchell P.O., Pavlath G.K. Systemic administration of the NF-κB inhibitor curcumin stimulates muscle regeneration after traumatic injury. Am J Physiol 1999, 277:C320-C329.
28. Tidball J.G., Villalta S.A. Regulatory interactions between muscle and the immune system during muscle regeneration. Am J Physiol Regul Integr Comp Physiol 2010, 298:R1173-R1187.
29. Tidball J.G. Inflammatory cell response to acute muscle injury. Med Sci Sports Exerc 1995, 27:1022-1032.
30. Tidball J.G. Inflammatory processes in muscle injury and repair. Am J Physiol Regul Integr Comp Physiol 2005, 288:R345-R353.
31. Warren G.L., Hulderman T., Jensen N., McKinstry M., Mishra M., Luster M.I., Simeonova P.P. Physiological role of tumor necrosis factor alpha in traumatic muscle injury. FASEB J 2002, 16:1630-1632.
32. Wilkin L.D., Merrick M.A., Kirby T.E., Devor S.T. Influence of therapeutic ultrasound on skeletal muscle regeneration following blunt contusion. Int J Sports Med 2004, 25:73-77.